HitPredict

Interactor 1: WWP2 (O00308)
NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (Atrophin-1-interacting protein 2) (AIP2) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2)
Gene: WWP2

Interactor 2: ANR44 (Q8N8A2)
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44)
Gene: ANKRD44

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.573

Property	Details
Experiments	25416956, 31515488
Identification Methods	two hybrid, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 870 Hs			1 993
+	Hs
		125040 WWP2_HUMAN (1-870): 0: 982: 100.00		ANR17_HUMAN (1-166): 1.11e-30: 133: 27.98
+	Hs
		808109 NEDD4_HUMAN (90-867): 0: 731: 35.94		ANK3_HUMAN (572-992): 6.43e-99: 345: 26.61
+	Hs
		274704 HUWE1_HUMAN (241-869): 7.77e-179: 575: 30.03		TRPA1_HUMAN (843-992): 1e-26: 120: 19.61
+	Hs
		1336115 SMUF1_HUMAN (1-385): 1.35e-45: 177: 17.77		ANR50_HUMAN (1-397): 1.15e-102: 353: 27.36
+	Hs
		1336102 SMUF1_HUMAN (1-385): 1.35e-45: 177: 17.77		ANFY1_HUMAN (2-536): 1.38e-78: 281: 19.57