HitPredict

Interactor 1: RN128 (Q8TEB7)
E3 ubiquitin-protein ligase RNF128 (EC 2.3.2.27) (Gene related to anergy in lymphocytes protein) (GRAIL) (RING finger protein 128) (RING-type E3 ubiquitin transferase RNF128)
Gene: RNF128

Interactor 2: RN128 (Q8TEB7)
E3 ubiquitin-protein ligase RNF128 (EC 2.3.2.27) (Gene related to anergy in lymphocytes protein) (GRAIL) (RING finger protein 128) (RING-type E3 ubiquitin transferase RNF128)
Gene: RNF128

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.840

The method score is based on:

Property Details
Experiments 31715145, 37011906, 12705856
Identification Methods affinity chromatography technology, pull down, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PA~PA, zf-RING_2~zf-RING_2
Common GO terms GO:0001818 - negative regulation of cytokine production
GO:0005737 - cytoplasm
GO:0005770 - late endosome
GO:0005783 - endoplasmic reticulum
GO:0005794 - Golgi apparatus
and 11 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 428
Hs

1 428
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024