Protein: TRI17
E3 ubiquitin-protein ligase TRIM17 (EC 2.3.2.27) (RING finger protein 16) (RING-type E3 ubiquitin transferase TRIM17) (Testis RING finger protein) (Tripartite motif-containing protein 17)

Gene: TRI17, TRIM17
Organism: Homo sapiens
Interactions: 90
UniProt ID: Q9Y577

Gene Ontology (top 5):
GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0005764 - lysosome
GO:0006914 - autophagy
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1439329

TRI39
E3 ubiquitin-protein ligase TRIM39

5

16

High-throughput

0.940

High

1388066

TRI44
Tripartite motif-containing protein 44

3

17

Small-scale

0.877

High

1357787

TRI41
E3 ubiquitin-protein ligase TRIM41

3

19

High-throughput

0.861

High

906839

UB2D1
Ubiquitin-conjugating enzyme E2 D1

3

20

Small-scale

0.852

High

982379

UB2D2
Ubiquitin-conjugating enzyme E2 D2

3

20

Small-scale

0.852

High

957257

UB2D3
Ubiquitin-conjugating enzyme E2 D3

2

20

Small-scale

0.791

High

909419

UB2E1
Ubiquitin-conjugating enzyme E2 E1

2

20

Small-scale

0.767

High

971359

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

20

High-throughput

0.698

High

1383951

UBE2W
Ubiquitin-conjugating enzyme E2 W

1

20

High-throughput

0.698

High

1490991

UB2D4
Ubiquitin-conjugating enzyme E2 D4

1

20

High-throughput

0.698

High

169805

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

3

7

High-throughput

0.667

High

508900

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

9

High-throughput

0.647

High

957877

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

20

High-throughput

0.647

High

1100584

TIF1B
Transcription intermediary factor 1-beta

1

20

Small-scale

0.618

High

1491498

TRI17
E3 ubiquitin-protein ligase TRIM17

1

16

Small-scale

0.618

High

1060144

BAX
Apoptosis regulator BAX

1

3

Small-scale

0.578

High

908798

MAT1
CDK-activating kinase assembly factor MAT1

1

5

High-throughput

0.541

High

1248456

LRSM1
E3 ubiquitin-protein ligase LRSAM1

1

4

High-throughput

0.541

High

1491428

TRAF6
TNF receptor-associated factor 6

1

19

High-throughput

0.541

High

1112402

MTMR1
Phosphatidylinositol-3-phosphate phosphatase MTMR1

1

2

High-throughput

0.536

High

1158812

KCC4
Calcium/calmodulin-dependent protein kinase type IV

1

3

High-throughput

0.536

High

255508

SNX2
Sorting nexin-2

1

0

High-throughput

0.513

High

127418

LEG8
Galectin-8

1

13

Small-scale

0.501

High

609852

LEG3
Galectin-3

1

13

Small-scale

0.501

High

894270

MEOX2
Homeobox protein MOX-2

1

11

High-throughput

0.481

High

1491399

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

16

High-throughput

0.481

High

330001

ZWINT
Outer kinetochore KNL1 complex subunit ZWINT

1

3

Small-scale

0.479

High

334645

LYPA2
Acyl-protein thioesterase 2

1

1

Small-scale

0.479

High

462085

HS90A
Heat shock protein HSP 90-alpha

1

14

High-throughput

0.479

High

468956

HS90B
Heat shock protein HSP 90-beta

1

16

High-throughput

0.479

High

599642

STMN1
Stathmin

1

1

Small-scale

0.479

High

840840

RS27
Small ribosomal subunit protein eS27

1

1

Small-scale

0.479

High

849426

RANG
Ran-specific GTPase-activating protein

1

3

Small-scale

0.479

High

946224

MLF1
Myeloid leukemia factor 1

1

1

High-throughput

0.479

High

964783

DCAF7
DDB1- and CUL4-associated factor 7

1

1

Small-scale

0.479

High

981390

RAB1A
Ras-related protein Rab-1A

1

2

Small-scale

0.479

High

1158643

B2LA1
Bcl-2-related protein A1

1

3

Small-scale

0.479

High

1259708

RS27L
Ribosomal protein eS27-like

1

1

Small-scale

0.479

High

1308620

NUDC3
NudC domain-containing protein 3

1

3

High-throughput

0.479

High

1316789

WDFY3
WD repeat and FYVE domain-containing protein 3

1

2

Small-scale

0.479

High

1316905

ASPM
Abnormal spindle-like microcephaly-associated protein

1

6

Small-scale

0.479

High

1352120

ES8L3
Epidermal growth factor receptor kinase substrate 8-like protein 3

1

7

Small-scale

0.479

High

1389435

RNF31
E3 ubiquitin-protein ligase RNF31

1

5

Small-scale

0.479

High

1394213

LRCH3
DISP complex protein LRCH3

1

2

Small-scale

0.479

High

1402657

SRPK1
SRSF protein kinase 1

1

7

Small-scale

0.479

High

1407505

TS101
Tumor susceptibility gene 101 protein

1

1

Small-scale

0.479

High

1413511

AASD1
Alanyl-tRNA editing protein Aarsd1

1

2

High-throughput

0.479

High

1419746

GTPB4
GTP-binding protein 4

1

2

Small-scale

0.479

High

1431449

EHD4
EH domain-containing protein 4

1

4

Small-scale

0.479

High

1431846

SLK
STE20-like serine/threonine-protein kinase

1

13

Small-scale

0.479

High

1460653

DBNL
Drebrin-like protein

1

9

Small-scale

0.479

High

1490539

NUDC
Nuclear migration protein nudC

1

3

High-throughput

0.479

High

1232654

Q6FHY5
MEOX2 protein

1

13

High-throughput

0.470

High

984602

RL30
Large ribosomal subunit protein eL30

1

0

Small-scale

0.458

High

1118361

EXOS2
Exosome complex component RRP4

1

0

Small-scale

0.458

High

1278522

PPR42
Protein phosphatase 1 regulatory subunit 42

1

0

Small-scale

0.458

High

1311329

CDAN1
Codanin-1

1

0

Small-scale

0.458

High

76593

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

1

High-throughput

0.437

High

788340

GPX4
Phospholipid hydroperoxide glutathione peroxidase GPX4

1

1

Small-scale

0.437

High

908623

LUM
Lumican

1

1

Small-scale

0.437

High

944965

CAR18
Caspase recruitment domain-containing protein 18

1

1

Small-scale

0.437

High

955901

GMFB
Glia maturation factor beta

1

3

Small-scale

0.437

High

1198807

Q53FC7
Heat shock 70 kDa protein 6

1

7

High-throughput

0.437

High

1245588

Q6PK50
HSP90AB1 protein

1

16

High-throughput

0.437

High

1384555

Q96BE0
Heat shock cognate 71 kDa protein

1

8

High-throughput

0.437

High

1429751

ADT4
ADP/ATP translocase 4

1

4

Small-scale

0.437

High

1430734

RBM38
RNA-binding protein 38

1

7

Small-scale

0.437

High

1437994

CYBP
Calcyclin-binding protein

1

1

High-throughput

0.437

High

1452027

TOR4A
Torsin-4A

1

1

Small-scale

0.437

High

1490981

NOP58
Nucleolar protein 58

1

5

Small-scale

0.437

High

557814

PEPD
Xaa-Pro dipeptidase

1

0

Small-scale

0.249

Low

914856

NDST1
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1

1

0

Small-scale

0.249

Low

939842

ATPK
ATP synthase F(0) complex subunit f, mitochondrial

1

0

Small-scale

0.249

Low

963252

LYSC
Lysozyme C

1

0

Small-scale

0.249

Low

974500

SMD1
Small nuclear ribonucleoprotein Sm D1

1

0

Small-scale

0.249

Low

1125096

RCN2
Reticulocalbin-2

1

0

Small-scale

0.249

Low

1136197

SPCS2
Signal peptidase complex subunit 2

1

0

Small-scale

0.249

Low

1165409

CC142
Coiled-coil domain-containing protein 142

1

0

Small-scale

0.249

Low

1219924

USPL1
SUMO-specific isopeptidase USPL1

1

0

Small-scale

0.249

Low

1335278

NECP1
Adaptin ear-binding coat-associated protein 1

1

0

Small-scale

0.249

Low

1380337

MYDGF
Myeloid-derived growth factor

1

0

Small-scale

0.249

Low

1391271

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

0

Small-scale

0.249

Low

1421097

EPT1
Ethanolaminephosphotransferase 1

1

0

Small-scale

0.249

Low

1449134

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

Small-scale

0.249

Low

1451518

RM22
Large ribosomal subunit protein uL22m

1

0

Small-scale

0.249

Low

1459650

SUSD2
Sushi domain-containing protein 2

1

0

Small-scale

0.249

Low

1491149

RM11
Large ribosomal subunit protein uL11m

1

0

Small-scale

0.249

Low

1491499

SPIN1
Spindlin-1

1

0

Small-scale

0.249

Low

1491500

RT18B
Small ribosomal subunit protein mS40

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025