HitPredict

Interactor 1: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Interactor 2: WWTR1 (Q9GZV5)
WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif)
Gene: WWTR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38280479
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1356 Hs			1 400
+	Hs
		808795 PARD3_HUMAN (1-1356): 0: 709: 100.00		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		1136433 PARD3_HUMAN (1-1356): 0: 709: 100.00		MAGI3_HUMAN (3-246): 4.83e-43: 162: 19.28
+	Hs
		1256866 PARD3_HUMAN (1-1356): 0: 709: 100.00		MAGI1_HUMAN (10-212): 9.04e-40: 153: 15.74
+	Hs
		280067 MPDZ_HUMAN (446-543): 1.36e-20: 101: 40.82		WWTR1_HUMAN (1-400): 5.62e-126: 370: 100.00
+	Hs
		1020213 PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50		WWTR1_HUMAN (1-400): 5.62e-126: 370: 100.00
+	Hs
		280032 MPDZ_HUMAN (446-543): 1.36e-20: 101: 40.82		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Dm
		1001633 Q0KHR3_DROME (42-1082): 6.25e-62: 235: 20.76		Q9W2L2_DROME (11-209): 8.85e-41: 156: 17.59
+	Hs
		808559 PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		808786 INADL_HUMAN (28-397): 1.09e-15: 85.1: 11.14		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		1199788 MAGI2_HUMAN (68-1181): 1.8e-38: 159: 13.66		MAGI1_HUMAN (10-212): 9.04e-40: 153: 15.74
+	Hs
		125592 INADL_HUMAN (28-397): 1.09e-15: 85.1: 11.14		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Mm
		1143518 DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98		MAGI3_MOUSE (3-246): 8.06e-44: 165: 18.88
+	Hs
		280050 MPDZ_HUMAN (446-543): 1.36e-20: 101: 40.82		KIBRA_HUMAN (123-265): 3.08e-45: 169: 18.88
+	Hs
		1220068 INADL_HUMAN (28-397): 1.09e-15: 85.1: 11.14		KIBRA_HUMAN (123-265): 3.08e-45: 169: 18.88
+	Hs
		1300658 MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16		MAGI1_HUMAN (10-212): 9.04e-40: 153: 15.74
+	Mm
		1143429 DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98		NED4L_MOUSE (129-395): 4.63e-24: 106: 11.96
+	Mm
		93273 DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98		E9PXB7_MOUSE (129-395): 7.76e-23: 102: 12.68
+	Hs
		1271021 DLG3_HUMAN (556-1119): 1.21e-27: 123: 13.01		NED4L_HUMAN (164-352): 3.03e-13: 73.5: 13.20
+	Hs
		280084 MPDZ_HUMAN (446-543): 1.36e-20: 101: 40.82		WWOX_HUMAN (111-236): 1.79e-18: 88.4: 21.09
+	Hs
		1299602 MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16		NED4L_HUMAN (164-352): 3.03e-13: 73.5: 13.20