Protein: NIPA1
Magnesium transporter NIPA1 (Non-imprinted in Prader-Willi/Angelman syndrome region protein 1) (Spastic paraplegia 6 protein)

Gene: NIPA1
Organism: Homo sapiens
Interactions: 178
UniProt ID: Q7RTP0

Gene Ontology (top 5):
GO:0005769 - early endosome
GO:0005886 - plasma membrane
GO:0015095 - magnesium ion transmembrane transporter activity
GO:0015693 - magnesium ion transport
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1273782

CCD47
PAT complex subunit CCDC47

2

1

High-throughput

0.601

High

1273816

CC167
Coiled-coil domain-containing protein 167

2

0

High-throughput

0.580

High

867978

GLR
Glucagon receptor

1

6

High-throughput

0.536

High

1273795

SMO
Protein smoothened

1

0

High-throughput

0.518

High

290251

TM1L1
TOM1-like protein 1

1

2

High-throughput

0.515

High

128007

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

2

High-throughput

0.445

High

128264

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

1

High-throughput

0.445

High

132127

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

3

High-throughput

0.445

High

136513

GOLI4
Golgi integral membrane protein 4

1

1

High-throughput

0.445

High

212436

SPIT2
Kunitz-type protease inhibitor 2

1

2

High-throughput

0.445

High

256476

TOM1
Target of Myb1 membrane trafficking protein

1

2

High-throughput

0.445

High

296364

ATRN
Attractin

1

1

High-throughput

0.445

High

342934

HERC2
E3 ubiquitin-protein ligase HERC2

1

4

High-throughput

0.445

High

363486

EGFR
Epidermal growth factor receptor

1

3

High-throughput

0.445

High

390636

TFR1
Transferrin receptor protein 1

1

2

High-throughput

0.445

High

417531

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.445

High

422429

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.445

High

439765

INSR
Insulin receptor

1

3

High-throughput

0.445

High

465558

IGF1R
Insulin-like growth factor 1 receptor

1

3

High-throughput

0.445

High

548528

MPRI
Cation-independent mannose-6-phosphate receptor

1

2

High-throughput

0.445

High

602894

INAR1
Interferon alpha/beta receptor 1

1

5

High-throughput

0.445

High

610387

PRS6A
26S proteasome regulatory subunit 6A

1

4

High-throughput

0.445

High

618267

CADH2
Cadherin-2

1

2

High-throughput

0.445

High

630553

RAB3B
Ras-related protein Rab-3B

1

1

High-throughput

0.445

High

648288

ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

1

2

High-throughput

0.445

High

693409

CERS1
Ceramide synthase 1

1

3

High-throughput

0.445

High

710332

EPHA2
Ephrin type-A receptor 2

1

3

High-throughput

0.445

High

778722

PRS7
26S proteasome regulatory subunit 7

1

3

High-throughput

0.445

High

787189

BMR1A
Bone morphogenetic protein receptor type-1A

1

1

High-throughput

0.445

High

820536

IL6RB
Interleukin-6 receptor subunit beta

1

5

High-throughput

0.445

High

839785

EPS15
Epidermal growth factor receptor substrate 15

1

1

High-throughput

0.445

High

841613

LIFR
Leukemia inhibitory factor receptor

1

5

High-throughput

0.445

High

851360

PRS6B
26S proteasome regulatory subunit 6B

1

3

High-throughput

0.445

High

880591

LMAN1
Protein ERGIC-53

1

1

High-throughput

0.445

High

906551

PSMD7
26S proteasome non-ATPase regulatory subunit 7

1

1

High-throughput

0.445

High

908025

VAMP7
Vesicle-associated membrane protein 7

1

1

High-throughput

0.445

High

921702

COPB
Coatomer subunit beta

1

3

High-throughput

0.445

High

921937

COPA
Coatomer subunit alpha

1

1

High-throughput

0.445

High

934230

BI1
Bax inhibitor 1

1

2

High-throughput

0.445

High

957960

RAB14
Ras-related protein Rab-14

1

1

High-throughput

0.445

High

968746

PRS4
26S proteasome regulatory subunit 4

1

3

High-throughput

0.445

High

968970

PRS8
26S proteasome regulatory subunit 8

1

4

High-throughput

0.445

High

975443

PRS10
26S proteasome regulatory subunit 10B

1

4

High-throughput

0.445

High

1047604

NOTC2
Neurogenic locus notch homolog protein 2

1

1

High-throughput

0.445

High

1055329

APLP2
Amyloid beta precursor like protein 2

1

2

High-throughput

0.445

High

1088190

MERTK
Tyrosine-protein kinase Mer

1

4

High-throughput

0.445

High

1098047

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

1

High-throughput

0.445

High

1101744

PTK7
Inactive tyrosine-protein kinase 7

1

1

High-throughput

0.445

High

1105811

ADA15
Disintegrin and metalloproteinase domain-containing protein 15

1

1

High-throughput

0.445

High

1105854

TMED1
Transmembrane emp24 domain-containing protein 1

1

8

High-throughput

0.445

High

1132287

GOGB1
Golgin subfamily B member 1

1

1

High-throughput

0.445

High

1249969

LRIG3
Leucine-rich repeats and immunoglobulin-like domains protein 3

1

1

High-throughput

0.445

High

1256337

AN13D
Ankyrin repeat domain-containing protein 13D

1

2

High-throughput

0.445

High

1256886

TM1L2
TOM1-like protein 2

1

2

High-throughput

0.445

High

1273762

ATG9A
Autophagy-related protein 9A

1

1

High-throughput

0.445

High

1273764

LRP10
Low-density lipoprotein receptor-related protein 10

1

1

High-throughput

0.445

High

1273769

MIRO2
Mitochondrial Rho GTPase 2

1

1

High-throughput

0.445

High

1273770

AN13A
Ankyrin repeat domain-containing protein 13A

1

1

High-throughput

0.445

High

1273771

AGRG2
Adhesion G-protein coupled receptor G2

1

5

High-throughput

0.445

High

1273772

NIPA2
Magnesium transporter NIPA2

1

2

High-throughput

0.445

High

1273774

RN149
E3 ubiquitin-protein ligase RNF149

1

4

High-throughput

0.445

High

1273775

CHSTE
Carbohydrate sulfotransferase 14

1

2

High-throughput

0.445

High

1273779

PO210
Nuclear pore membrane glycoprotein 210

1

1

High-throughput

0.445

High

1273783

ARL8A
ADP-ribosylation factor-like protein 8A

1

1

High-throughput

0.445

High

1273785

PKHB2
Pleckstrin homology domain-containing family B member 2

1

2

High-throughput

0.445

High

1273787

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

3

High-throughput

0.445

High

1273792

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

1

High-throughput

0.445

High

1273793

OSMR
Oncostatin-M-specific receptor subunit beta

1

5

High-throughput

0.445

High

1273799

TMM59
Transmembrane protein 59

1

1

High-throughput

0.445

High

1273802

S38A1
Sodium-coupled neutral amino acid symporter 1

1

1

High-throughput

0.445

High

1273803

GCP60
Golgi resident protein GCP60

1

1

High-throughput

0.445

High

1273805

AT133
Polyamine-transporting ATPase 13A3

1

9

High-throughput

0.445

High

1273807

AT131
Endoplasmic reticulum transmembrane helix translocase

1

7

High-throughput

0.445

High

1273808

CHSTB
Carbohydrate sulfotransferase 11

1

2

High-throughput

0.445

High

1273809

IL1AP
Interleukin-1 receptor accessory protein

1

1

High-throughput

0.445

High

1273810

ITM2C
Integral membrane protein 2C

1

1

High-throughput

0.445

High

1273811

SERC1
Serine incorporator 1

1

1

High-throughput

0.445

High

1273812

T106B
Transmembrane protein 106B

1

2

High-throughput

0.445

High

1273815

ARL8B
ADP-ribosylation factor-like protein 8B

1

2

High-throughput

0.445

High

1273817

VAPA
Vesicle-associated membrane protein-associated protein A

1

3

High-throughput

0.445

High

1273819

PKHB1
Pleckstrin homology domain-containing family B member 1

1

2

High-throughput

0.445

High

1273820

UBQL2
Ubiquilin-2

1

1

High-throughput

0.445

High

1273822

LCAP
Leucyl-cystinyl aminopeptidase

1

1

High-throughput

0.445

High

1273823

RABX5
Rab5 GDP/GTP exchange factor

1

1

High-throughput

0.445

High

1273824

MA1B1
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

1

1

High-throughput

0.445

High

1273825

AMFR
E3 ubiquitin-protein ligase AMFR

1

3

High-throughput

0.445

High

1273827

PCDGK
Protocadherin gamma-C3

1

1

High-throughput

0.445

High

1273830

ITM2B
Integral membrane protein 2B

1

1

High-throughput

0.445

High

1273834

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

1

1

High-throughput

0.445

High

1273835

RHBD3
Rhomboid domain-containing protein 3

1

2

High-throughput

0.445

High

1273838

LRP12
Low-density lipoprotein receptor-related protein 12

1

1

High-throughput

0.445

High

1273839

PCDGH
Protocadherin gamma-B5

1

1

High-throughput

0.445

High

230345

CREB3
Cyclic AMP-responsive element-binding protein 3

1

0

High-throughput

0.438

High

141937

PODXL
Podocalyxin

1

0

High-throughput

0.426

High

163320

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

0

High-throughput

0.426

High

300005

CBPD
Carboxypeptidase D

1

0

High-throughput

0.426

High

654985

ITA6
Integrin alpha-6

1

0

High-throughput

0.426

High

987395

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

0

High-throughput

0.426

High

1006018

ASIC1
Acid-sensing ion channel 1

1

0

High-throughput

0.426

High

1022411

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.426

High

1128761

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.426

High

1162323

CEGT
Ceramide glucosyltransferase

1

0

High-throughput

0.426

High

1218413

CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase

1

0

High-throughput

0.426

High

1238340

RETST
All-trans-retinol 13,14-reductase

1

0

High-throughput

0.426

High

1242449

CNNM4
Metal transporter CNNM4

1

0

High-throughput

0.426

High

1273768

IPRI
Inositol 1,4,5-trisphosphate receptor-interacting protein

1

0

High-throughput

0.426

High

1273780

ZFN2B
AN1-type zinc finger protein 2B

1

0

High-throughput

0.426

High

1273789

WRIP1
ATPase WRNIP1

1

0

High-throughput

0.426

High

1273794

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.426

High

1273800

SEM4C
Semaphorin-4C

1

0

High-throughput

0.426

High

1273801

TOLIP
Toll-interacting protein

1

0

High-throughput

0.426

High

1273804

RABE2
Rab GTPase-binding effector protein 2

1

0

High-throughput

0.426

High

1273806

VEZA
Vezatin

1

0

High-throughput

0.426

High

1273814

CC50A
Cell cycle control protein 50A

1

0

High-throughput

0.426

High

1273828

PSD13
26S proteasome non-ATPase regulatory subunit 13

1

0

High-throughput

0.426

High

1273829

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

0

High-throughput

0.426

High

1273836

TCAF1
TRPM8 channel-associated factor 1

1

0

High-throughput

0.426

High

1273841

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

0

High-throughput

0.426

High

66010

U119B
Protein unc-119 homolog B

1

1

High-throughput

0.407

High

138192

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

1

High-throughput

0.407

High

165364

PSA7
Proteasome subunit alpha type-7

1

4

High-throughput

0.407

High

165605

SCAM3
Secretory carrier-associated membrane protein 3

1

1

High-throughput

0.407

High

294787

CAN15
Calpain-15

1

1

High-throughput

0.407

High

322959

UBP19
Ubiquitin carboxyl-terminal hydrolase 19

1

2

High-throughput

0.407

High

324007

CSTN1
Calsyntenin-1

1

5

High-throughput

0.407

High

633728

PSB1
Proteasome subunit beta type-1

1

6

High-throughput

0.407

High

680924

PSA1
Proteasome subunit alpha type-1

1

4

High-throughput

0.407

High

681191

PSA2
Proteasome subunit alpha type-2

1

5

High-throughput

0.407

High

681428

PSA3
Proteasome subunit alpha type-3

1

4

High-throughput

0.407

High

681676

PSA4
Proteasome subunit alpha type-4

1

4

High-throughput

0.407

High

700674

PSA5
Proteasome subunit alpha type-5

1

4

High-throughput

0.407

High

700916

PSB4
Proteasome subunit beta type-4

1

7

High-throughput

0.407

High

701179

PSB5
Proteasome subunit beta type-5

1

4

High-throughput

0.407

High

717520

PDIA3
Protein disulfide-isomerase A3

1

1

High-throughput

0.407

High

885482

MA2A2
Alpha-mannosidase 2x

1

3

High-throughput

0.407

High

887556

PSB3
Proteasome subunit beta type-3

1

4

High-throughput

0.407

High

931549

RD23A
UV excision repair protein RAD23 homolog A

1

3

High-throughput

0.407

High

931676

RD23B
UV excision repair protein RAD23 homolog B

1

3

High-throughput

0.407

High

954846

PSA6
Proteasome subunit alpha type-6

1

5

High-throughput

0.407

High

1093378

TRI32
E3 ubiquitin-protein ligase TRIM32

1

1

High-throughput

0.407

High

1105143

U119A
Protein unc-119 homolog A

1

1

High-throughput

0.407

High

1136548

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

1

High-throughput

0.407

High

1273763

MAVS
Mitochondrial antiviral-signaling protein

1

1

High-throughput

0.407

High

1273773

UBAC2
Ubiquitin-associated domain-containing protein 2

1

1

High-throughput

0.407

High

1273778

RHBL4
Rhomboid-related protein 4

1

2

High-throughput

0.407

High

1273784

FAF2
FAS-associated factor 2

1

3

High-throughput

0.407

High

1273786

RNF31
E3 ubiquitin-protein ligase RNF31

1

1

High-throughput

0.407

High

1273791

PSB7
Proteasome subunit beta type-7

1

3

High-throughput

0.407

High

1273796

CSTN3
Calsyntenin-3

1

5

High-throughput

0.407

High

1273797

PGAP4
GPI-N-acetylgalactosamine transferase PGAP4

1

1

High-throughput

0.407

High

1273798

RN126
E3 ubiquitin-protein ligase RNF126

1

1

High-throughput

0.407

High

1273813

NFIP2
NEDD4 family-interacting protein 2

1

1

High-throughput

0.407

High

1273818

COPG2
Coatomer subunit gamma-2

1

3

High-throughput

0.407

High

1273826

EPDR1
Mammalian ependymin-related protein 1

1

2

High-throughput

0.407

High

1273831

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

2

High-throughput

0.407

High

1273833

TMED5
Transmembrane emp24 domain-containing protein 5

1

8

High-throughput

0.407

High

1273837

RN115
E3 ubiquitin-protein ligase RNF115

1

2

High-throughput

0.407

High

1273840

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

1

High-throughput

0.407

High

1273781

SELM
Selenoprotein M

2

0

High-throughput

0.316

High

958978

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.249

Low

322149

GLCE
D-glucuronyl C5-epimerase

1

0

High-throughput

0.232

Low

533703

CLUS
Clusterin

1

0

High-throughput

0.232

Low

679366

DNJB2
DnaJ homolog subfamily B member 2

1

0

High-throughput

0.232

Low

853483

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

1

0

High-throughput

0.232

Low

933675

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

0

High-throughput

0.232

Low

952441

UB2G2
Ubiquitin-conjugating enzyme E2 G2

1

0

High-throughput

0.232

Low

1136714

LAP4A
Lysosomal-associated transmembrane protein 4A

1

0

High-throughput

0.232

Low

1218149

CAHD1
VWFA and cache domain-containing protein 1

1

0

High-throughput

0.232

Low

1273765

PABP2
Polyadenylate-binding protein 2

1

0

High-throughput

0.232

Low

1273766

TAXB1
Tax1-binding protein 1

1

0

High-throughput

0.232

Low

1273767

PLD3
5'-3' exonuclease PLD3

1

0

High-throughput

0.232

Low

1273776

TBC15
TBC1 domain family member 15

1

0

High-throughput

0.232

Low

1273777

RDH11
Retinol dehydrogenase 11

1

0

High-throughput

0.232

Low

1273788

H6ST2
Heparan-sulfate 6-O-sulfotransferase 2

1

0

High-throughput

0.232

Low

1273790

CP2S1
Cytochrome P450 2S1

1

0

High-throughput

0.232

Low

1273821

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

0

High-throughput

0.232

Low

1273832

ZDHC9
Palmitoyltransferase ZDHHC9

1

0

High-throughput

0.232

Low

1273842

TX264
Testis-expressed protein 264

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025