Interactor 1: RGMC (Q6ZVN8)
Hemojuvelin (Hemochromatosis type 2 protein) (Hemojuvelin BMP coreceptor) (RGM domain family member C)
Gene: HJV
Interactor 2: NEO1 (Q92859)
Neogenin (Immunoglobulin superfamily DCC subclass member 2)
Gene: NEO1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.51 | 1.00 | 0.716 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18335997 |
| Identification Methods | surface plasmon resonance, pull down, static light scattering |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | RGM_C~fn3, RGM_N~fn3 |
| Common GO terms | GO:0005886 - plasma membrane GO:0006879 - intracellular iron ion homeostasis GO:0009986 - cell surface GO:0060586 - multicellular organismal-level iron ion homeostasis GO:0098797 - plasma membrane protein complex |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
