Interactor 1: CDC7 (O00311)
Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1)
Gene: CDC7

Interactor 2: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.812

The method score is based on:

Property Details
Experiments 17927916, 10846177
Identification Methods affinity chromatography technology, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 5 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 574
Hs

1 298
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024