Protein: AP4M1
AP-4 complex subunit mu-1 (AP-4 adaptor complex mu subunit) (Adaptor-related protein complex 4 subunit mu-1) (Mu subunit of AP-4) (Mu-adaptin-related protein 2) (mu-ARP2) (Mu4-adaptin) (mu4)

Gene: AP4M1
Organism: Homo sapiens
Interactions: 53
UniProt ID: O00189

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0005769 - early endosome
GO:0005802 - trans-Golgi network
GO:0005829 - cytosol
GO:0006605 - protein targeting

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

125857

AP4E1
AP-4 complex subunit epsilon-1

3

20

Small-scale

0.861

High

125863

AP4B1
AP-4 complex subunit beta-1

2

20

Small-scale

0.821

High

125830

ARF1
ADP-ribosylation factor 1

2

2

Small-scale

0.757

High

125862

AP4S1
AP-4 complex subunit sigma-1

1

19

High-throughput

0.691

High

125850

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

3

1

High-throughput

0.675

High

125851

AP4AT
AP-4 complex accessory subunit Tepsin

3

2

Small-scale

0.673

High

125831

ARF5
ADP-ribosylation factor 5

1

2

High-throughput

0.618

High

125843

ATG9A
Autophagy-related protein 9A

2

6

Small-scale

0.601

High

125855

DISC1
Disrupted in schizophrenia 1 protein

2

1

High-throughput

0.601

High

125827

FNTA
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

2

0

High-throughput

0.580

High

125856

HOOK1
Protein Hook homolog 1

2

8

Small-scale

0.548

High

125821

RALA
Ras-related protein Ral-A

1

7

High-throughput

0.536

High

125826

AKT2
RAC-beta serine/threonine-protein kinase

1

5

High-throughput

0.536

High

125844

SPRE2
Sprouty-related, EVH1 domain-containing protein 2

1

1

High-throughput

0.536

High

125822

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

0

High-throughput

0.513

High

125824

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.513

High

125840

ZN318
Zinc finger protein 318

1

0

High-throughput

0.513

High

125848

HOOK2
Protein Hook homolog 2

1

8

Small-scale

0.508

High

125816

ZBT22
Zinc finger and BTB domain-containing protein 22

1

3

High-throughput

0.494

High

125859

DDX52
Probable ATP-dependent RNA helicase DDX52

1

3

High-throughput

0.494

High

125814

CBX4
E3 SUMO-protein ligase CBX4

1

1

High-throughput

0.489

High

125847

TFB1M
Dimethyladenosine transferase 1, mitochondrial

1

1

High-throughput

0.489

High

125854

WDR76
WD repeat-containing protein 76

1

3

High-throughput

0.489

High

125815

XPO1
Exportin-1

1

13

High-throughput

0.479

High

125817

PRKN
E3 ubiquitin-protein ligase parkin

1

8

High-throughput

0.479

High

125828

PLK1
Serine/threonine-protein kinase PLK1

1

8

High-throughput

0.479

High

125832

H33
Histone H3.3

1

2

High-throughput

0.479

High

125834

ACY1
Aminoacylase-1

1

1

High-throughput

0.479

High

125842

KRA52
Keratin-associated protein 5-2

1

0

High-throughput

0.460

High

125819

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.458

High

125829

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

0

High-throughput

0.458

High

125837

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

7

Small-scale

0.439

High

125823

IFM1
Interferon-induced transmembrane protein 1

1

3

High-throughput

0.437

High

125833

IFM3
Interferon-induced transmembrane protein 3

1

3

High-throughput

0.437

High

125838

SF3B2
Splicing factor 3B subunit 2

1

2

High-throughput

0.437

High

125846

FHI1B
FHF complex subunit HOOK-interacting protein 1B

1

1

High-throughput

0.437

High

125858

CD11A
Cyclin-dependent kinase 11A

1

2

High-throughput

0.437

High

125835

FHI1A
FHF complex subunit HOOK-interacting protein 1A

1

1

Small-scale

0.417

High

76331

B4DNW0
Aminoacylase-1

1

1

High-throughput

0.407

High

114524

H0YEX5
Splicing factor 3b subunit 2

1

2

High-throughput

0.407

High

117238

K7EK07
Histone H3

1

2

High-throughput

0.407

High

125825

CD11B
Cyclin-dependent kinase 11B

1

2

High-throughput

0.407

High

125853

SUV92
Histone-lysine N-methyltransferase SUV39H2

2

0

High-throughput

0.328

High

125820

CTF8
Chromosome transmission fidelity protein 8 homolog

1

0

High-throughput

0.282

High

125818

TYW4
tRNA wybutosine-synthesizing protein 4

1

0

High-throughput

0.279

Low

125836

GALT2
Polypeptide N-acetylgalactosaminyltransferase 2

1

0

High-throughput

0.279

Low

125839

NPAT
Protein NPAT

1

0

High-throughput

0.279

Low

125841

ARID2
AT-rich interactive domain-containing protein 2

1

0

High-throughput

0.279

Low

125845

ARPIN
Arpin

1

0

High-throughput

0.279

Low

125849

RM48
Large ribosomal subunit protein mL48

1

0

High-throughput

0.279

Low

125852

TIM29
Mitochondrial import inner membrane translocase subunit Tim29

1

0

High-throughput

0.279

Low

125860

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.279

Low

125861

RT23
Small ribosomal subunit protein mS23

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025