HitPredict

Interactor 1: CSN6A (Q8W206)
COP9 signalosome complex subunit 6a (AtCSN6a) (Signalosome subunit 6a)
Gene: CSN6A

Interactor 2: CSN3 (Q8W575)
COP9 signalosome complex subunit 3 (Signalosome subunit 3) (Protein FUSCA 11)
Gene: CSN3

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.828

Property	Details
Experiments	12615944, 15703063, 11701877
Identification Methods	two hybrid, tandem affinity purification
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	JAB~PCI, MitMem_reg~PCI
Common GO terms	GO:0000338 - protein deneddylation GO:0005737 - cytoplasm GO:0006511 - ubiquitin-dependent protein catabolic process GO:0008180 - COP9 signalosome GO:0009585 - red, far-red light phototransduction
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 317 At			1 429
+	Hs
		1185012 CSN6_HUMAN (1-307): 9.13e-106: 313: 37.86		CSN3_HUMAN (6-428): 3.09e-116: 347: 37.76
+	Dm
		627121 PSMD7_DROME (1-312): 4.72e-92: 278: 21.56		PSMD3_DROME (8-420): 9.69e-100: 308: 19.72
+	Hs
		198579 PSMD7_HUMAN (7-308): 1.83e-89: 272: 21.36		PSMD3_HUMAN (47-424): 2.86e-96: 300: 20.51
+	Hs
		121804 CSN6_HUMAN (1-307): 9.13e-106: 313: 37.86		PSD11_HUMAN (55-393): 6.12e-81: 257: 13.19
+	Hs
		897267 CSN6_HUMAN (1-307): 9.13e-106: 313: 37.86		CSN2_HUMAN (33-384): 4.6e-73: 237: 11.17
+	Mm
		291866 CSN6_MOUSE (1-307): 9.6e-105: 310: 37.86		CSN2_MOUSE (33-384): 4.6e-73: 237: 11.17
+	Dm
		640773 PSMD7_DROME (1-312): 4.72e-92: 278: 21.56		PSD11_DROME (55-394): 6.36e-79: 252: 13.16
+	Hs
		121709 PSMD7_HUMAN (7-308): 1.83e-89: 272: 21.36		PSD11_HUMAN (55-393): 6.12e-81: 257: 13.19
+	Dm
		1277032 CSN6_DROME (1-307): 8.35e-101: 301: 37.42		CSN2_DROME (36-384): 4.86e-68: 224: 12.09
+	Sc
		766895 RPN8_YEAST (9-312): 1.25e-73: 231: 19.76		RPN3_YEAST (49-418): 1.79e-76: 248: 16.54
+	Zm
		46755 B4FLQ8_MAIZE (2-161): 4.5e-20: 90.2: 13.69		A0A3L6E9W8_MAIZE (5-427): 1.64e-129: 383: 51.39
+	Dm
		1358198 CSN6_DROME (1-307): 8.35e-101: 301: 37.42		CSN4_DROME (72-396): 5.67e-44: 159: 11.44
+	Ce
		136316 CSN6_CAEEL (2-301): 6.01e-65: 212: 23.03		CSN2_CAEEL (30-366): 1.13e-71: 235: 12.46
+	Sc
		996269 RPN8_YEAST (9-312): 1.25e-73: 231: 19.76		RPN6_YEAST (51-386): 1.27e-62: 210: 12.11
+	Dm
		1277039 CSN5_DROME (50-188): 8.31e-21: 92.9: 12.84		CSN2_DROME (36-384): 4.86e-68: 224: 12.09
+	Sp
		293445 CSN5_SCHPO (58-180): 2.55e-28: 112: 17.42		CSN2_SCHPO (53-386): 9.38e-52: 181: 9.77
+	Dm
		1358216 CSN5_DROME (50-188): 8.31e-21: 92.9: 12.84		CSN4_DROME (72-396): 5.67e-44: 159: 11.44