HitPredict

Interactor 1: EHMT2 (Q96KQ7)
Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a)
Gene: EHMT2

Interactor 2: UHRF2 (Q96PU4)
E3 ubiquitin-protein ligase UHRF2 (EC 2.3.2.27) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear protein 97) (Nuclear zinc finger protein Np97) (RING finger protein 107) (RING-type E3 ubiquitin transferase UHRF2) (Ubiquitin-like PHD and RING finger domain-containing protein 2) (Ubiquitin-like-containing PHD and RING finger domains protein 2)
Gene: UHRF2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	27114453, 22064703
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SAD_SRA~SET
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1210 Hs			1 802
+	Hs
		1296399 EHMT2_HUMAN (21-1210): 0: 909: 100.00		UHRF1_HUMAN (1-802): 0: 817: 53.01
+	Mm
		1257482 EHMT2_MOUSE (9-1210): 0: 870: 94.44		UHRF1_MOUSE (1-802): 0: 789: 51.58
+	Hs
		1059797 EHMT2_HUMAN (21-1210): 0: 909: 100.00		CHD4_HUMAN (294-594): 1.5e-54: 207: 12.84
+	Hs
		203773 SUV91_HUMAN (861-1179): 1.67e-78: 266: 30.51		UHRF1_HUMAN (1-802): 0: 817: 53.01
+	Hs
		782374 EHMT2_HUMAN (21-1210): 0: 909: 100.00		KDM5C_HUMAN (251-428): 3.26e-34: 143: 16.36
+	Hs
		1059880 EHMT1_HUMAN (1-1209): 0: 685: 45.63		CHD4_HUMAN (294-594): 1.5e-54: 207: 12.84
+	Hs
		203687 SUV91_HUMAN (861-1179): 1.67e-78: 266: 30.51		CHD4_HUMAN (294-594): 1.5e-54: 207: 12.84