HitPredict

Interactor 1: CSN6A (Q8W206)
COP9 signalosome complex subunit 6a (AtCSN6a) (Signalosome subunit 6a)
Gene: CSN6A

Interactor 2: CSN7 (Q94JU3)
COP9 signalosome complex subunit 7 (CSN complex subunit 7) (Protein FUSCA 5)
Gene: CSN7

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.835

Property	Details
Experiments	11742986, 12615944, 11701877
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	JAB~PCI, MitMem_reg~PCI
Common GO terms	GO:0000338 - protein deneddylation GO:0005737 - cytoplasm GO:0008180 - COP9 signalosome GO:0009585 - red, far-red light phototransduction GO:0010387 - COP9 signalosome assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 At			1 260
+	At
		1258849 CSN6B_ARATH (1-317): 2.85e-122: 355: 87.38		CSN7_ARATH (1-260): 4.96e-98: 288: 100.00
+	Hs
		1184985 CSN6_HUMAN (1-307): 9.13e-106: 313: 37.86		CSN7B_HUMAN (1-255): 1.99e-79: 241: 32.56
+	Dm
		1359989 CSN6_DROME (1-307): 8.35e-101: 301: 37.42		CSN7_DROME (2-257): 6.25e-81: 246: 32.56
+	Hs
		1185003 CSN6_HUMAN (1-307): 9.13e-106: 313: 37.86		CSN7A_HUMAN (12-255): 1.4e-75: 232: 30.28
+	Hs
		91400 E7EM64_HUMAN (1-307): 7.34e-106: 313: 37.86		CSN7A_HUMAN (12-255): 1.4e-75: 232: 30.28
+	Hs
		124889 EIF3F_HUMAN (1-297): 9.85e-97: 291: 24.00		EIF3M_HUMAN (2-188): 3.07e-54: 181: 22.17
+	Hs
		849285 PSMD7_HUMAN (7-308): 1.83e-89: 272: 21.36		PSD13_HUMAN (16-191): 1.36e-54: 181: 17.20
+	Dm
		1177360 EI3F1_DROME (5-303): 6.74e-91: 273: 18.75		EIF3M_DROME (3-205): 2.2e-53: 179: 21.70
+	Dm
		640774 PSMD7_DROME (1-312): 4.72e-92: 278: 21.56		Q7KMP8_DROME (24-191): 1.43e-51: 174: 20.23
+	At
		1278361 EIF3H_ARATH (5-272): 2.16e-44: 156: 10.44		CSN7_ARATH (1-260): 4.96e-98: 288: 100.00
+	Hs
		849293 PSMD7_HUMAN (7-308): 1.83e-89: 272: 21.36		Q9Y6E3_HUMAN (16-191): 1.97e-47: 163: 16.58
+	Ce
		247773 O61792_CAEEL (7-315): 8.88e-85: 261: 21.59		Q22253_CAEEL (11-191): 7.45e-51: 172: 18.85
+	Dm
		51504 EI3F2_DROME (1-297): 4.4e-77: 238: 18.75		EIF3M_DROME (3-205): 2.2e-53: 179: 21.70
+	Sp
		251463 RPN8_SCHPO (1-300): 7.03e-79: 245: 22.29		RPN9_SCHPO (15-189): 7.89e-43: 151: 17.55
+	Sc
		978506 RPN8_YEAST (9-312): 1.25e-73: 231: 19.76		RPN9_YEAST (11-191): 1.48e-46: 161: 15.18
+	Ce
		1090428 EIF3F_CAEEL (6-297): 1.57e-72: 227: 17.48		EIF3M_CAEEL (2-216): 1.3e-44: 156: 19.73
+	Sp
		195128 EIF3F_SCHPO (2-301): 5.23e-77: 239: 20.82		EIF3M_SCHPO (2-206): 4.96e-40: 144: 24.07
+	Hs
		177046 EIF3H_HUMAN (3-296): 2.66e-59: 195: 14.33		EIF3M_HUMAN (2-188): 3.07e-54: 181: 22.17
+	Dm
		1177352 EIF3H_DROME (4-294): 3.03e-54: 181: 14.47		EIF3M_DROME (3-205): 2.2e-53: 179: 21.70
+	An
		961358 CSN6_EMENI (4-313): 3.81e-45: 159: 26.00		CSN7_EMENI (1-221): 8.33e-44: 152: 30.00