HitPredict

Interactor 1: NET5 (Q8WTR8)
Netrin-5 (Netrin-1-like protein)
Gene: NTN5

Interactor 2: LRP1B (Q9NZR2)
Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT)
Gene: LRP1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Laminin_EGF~Ldl_recept_b
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 489 Hs			1 4599
+	Hs
		1259455 NET5_HUMAN (1-489): 1.06e-87: 278: 100.00		SORL_HUMAN (4318-4575): 1.89e-12: 76.8: 11.24
+	Hs
		804299 NET5_HUMAN (1-489): 1.06e-87: 278: 100.00		NOTC1_HUMAN (12-229): 5.06e-12: 75.3: 14.10
+	Hs
		351091 NET5_HUMAN (1-489): 1.06e-87: 278: 100.00		LDLR_HUMAN (30-277): 8.85e-12: 74.1: 17.72
+	Hs
		957630 NET5_HUMAN (1-489): 1.06e-87: 278: 100.00		LRP2_HUMAN (4299-4586): 2.33e-10: 69.9: 9.18
+	Hs
		980475 NET5_HUMAN (1-489): 1.06e-87: 278: 100.00		NOTC2_HUMAN (11-260): 3.49e-09: 66: 14.40
+	Hs
		254285 NET5_HUMAN (1-489): 1.06e-87: 278: 100.00		LRP4_HUMAN (3711-3893): 9.84e-09: 64.5: 21.29
+	Hs
		317789 NET1_HUMAN (58-476): 4.08e-73: 244: 38.62		NOTC2_HUMAN (11-260): 3.49e-09: 66: 14.40
+	Dm
		1098542 NETB_DROME (143-472): 9.84e-53: 192: 31.10		Q8IRV8_DROME (1063-1169): 3.12e-11: 72.8: 35.71
+	Dm
		422762 NETB_DROME (143-472): 9.84e-53: 192: 31.10		NOTCH_DROME (14-189): 1.52e-10: 70.3: 15.74
+	Hs
		624332 TENA_HUMAN (10-342): 2.3e-43: 166: 12.43		NID2_HUMAN (4360-4522): 5.4e-12: 74.9: 10.66
+	Hs
		502831 LAMC1_HUMAN (124-444): 6.82e-27: 117: 18.77		NID2_HUMAN (4360-4522): 5.4e-12: 74.9: 10.66
+	Dm
		422715 LAMC1_DROME (20-327): 1.21e-27: 119: 15.82		NOTCH_DROME (14-189): 1.52e-10: 70.3: 15.74
+	Hs
		502808 LAMC1_HUMAN (124-444): 6.82e-27: 117: 18.77		NID1_HUMAN (3473-3718): 1.32e-09: 67.1: 13.83
+	Hs
		537530 LAMC3_HUMAN (20-326): 3.25e-27: 117: 17.98		NID1_HUMAN (3473-3718): 1.32e-09: 67.1: 13.83
+	Dm
		52252 LAMC1_DROME (20-327): 1.21e-27: 119: 15.82		A1Z7C4_DROME (4354-4570): 8.46e-09: 64.5: 11.01
+	Hs
		877411 LAMB2_HUMAN (89-313): 5.5e-20: 96: 17.80		NID2_HUMAN (4360-4522): 5.4e-12: 74.9: 10.66
+	Hs
		1048403 LAMA4_HUMAN (252-383): 1.09e-17: 88.7: 17.29		NID2_HUMAN (4360-4522): 5.4e-12: 74.9: 10.66
+	Hs
		877404 LAMB2_HUMAN (89-313): 5.5e-20: 96: 17.80		NOTC2_HUMAN (11-260): 3.49e-09: 66: 14.40
+	Dm
		52251 LAMB1_DROME (19-313): 5.72e-17: 86.4: 17.59		A1Z7C4_DROME (4354-4570): 8.46e-09: 64.5: 11.01
+	Mm
		358675 LAMC1_MOUSE (240-449): 3.8e-14: 77.5: 13.33		NID1_MOUSE (2435-2650): 1.67e-09: 66.8: 10.31