HitPredict

Interactor 1: NET5 (Q8WTR8)
Netrin-5 (Netrin-1-like protein)
Gene: NTN5

Interactor 2: FBLN5 (Q9UBX5)
Fibulin-5 (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50)
Gene: FBLN5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 489 Hs			1 448
+	Dm
		246789 NETA_DROME (14-471): 2.79e-83: 273: 24.49		TENM_DROME (206-440): 5.16e-26: 113: 11.69
+	Hs
		1231788 NET5_HUMAN (1-489): 1.06e-87: 278: 100.00		LTBP4_HUMAN (9-286): 1.82e-19: 93.6: 24.32
+	Hs
		804299 NET5_HUMAN (1-489): 1.06e-87: 278: 100.00		NOTC1_HUMAN (5-391): 1.25e-18: 91.1: 13.16
+	Hs
		1059024 NET5_HUMAN (1-489): 1.06e-87: 278: 100.00		LTBP1_HUMAN (4-286): 1.43e-13: 75.2: 19.14
+	Hs
		980475 NET5_HUMAN (1-489): 1.06e-87: 278: 100.00		NOTC2_HUMAN (3-312): 4.71e-11: 67.2: 15.67
+	Hs
		724350 NET5_HUMAN (1-489): 1.06e-87: 278: 100.00		FBN1_HUMAN (27-367): 4.64e-09: 61: 17.71
+	Hs
		724385 NET5_HUMAN (1-489): 1.06e-87: 278: 100.00		FBN2_HUMAN (7-113): 5.15e-09: 60.9: 22.43
+	Hs
		317789 NET1_HUMAN (58-476): 4.08e-73: 244: 38.62		NOTC2_HUMAN (3-312): 4.71e-11: 67.2: 15.67
+	Dm
		246790 NETB_DROME (143-472): 9.84e-53: 192: 31.10		TENM_DROME (206-440): 5.16e-26: 113: 11.69
+	Dm
		422762 NETB_DROME (143-472): 9.84e-53: 192: 31.10		NOTCH_DROME (3-343): 1.45e-14: 78.4: 12.89
+	Dm
		1099002 NETB_DROME (143-472): 9.84e-53: 192: 31.10		TENA_DROME (2-107): 4.9e-10: 64.1: 11.41
+	Rn
		250561 CUBN_RAT (11-321): 5.85e-28: 120: 10.14		CUBN_RAT (3-217): 5.1e-26: 113: 16.59
+	Dm
		247258 TENA_DROME (229-476): 1.01e-17: 88.7: 13.89		TENM_DROME (206-440): 5.16e-26: 113: 11.69
+	Dm
		422715 LAMC1_DROME (20-327): 1.21e-27: 119: 15.82		NOTCH_DROME (3-343): 1.45e-14: 78.4: 12.89
+	Hs
		1053539 NTNG1_HUMAN (153-311): 2.56e-25: 110: 34.50		GAS6_HUMAN (113-211): 2.92e-15: 80.1: 40.39
+	Dm
		246859 Q8IP51_DROME (66-273): 6.45e-13: 73.7: 14.55		TENM_DROME (206-440): 5.16e-26: 113: 11.69
+	Hs
		877405 LAMB2_HUMAN (89-313): 5.5e-20: 96: 17.80		FBLN3_HUMAN (3-214): 1.13e-14: 78: 22.62
+	Hs
		877404 LAMB2_HUMAN (89-313): 5.5e-20: 96: 17.80		NOTC2_HUMAN (3-312): 4.71e-11: 67.2: 15.67
+	Dm
		90684 E1JHA6_DROME (120-460): 4.09e-13: 74.5: 10.63		NOTCH_DROME (3-343): 1.45e-14: 78.4: 12.89
+	Dm
		1375758 TENA_DROME (229-476): 1.01e-17: 88.7: 13.89		TENA_DROME (2-107): 4.9e-10: 64.1: 11.41