Protein: ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A (EC 3.6.5.-) (Cobalamin synthase W domain-containing protein 1) (COBW domain-containing protein 1) (NPC-A-6 COBW domain-containing protein 1) (NPC-A-6)

Gene: ZNG1A
Organism: Homo sapiens
Interactions: 184
UniProt ID: Q9BRT8

Gene Ontology (top 5):
GO:0001822 - kidney development
GO:0005525 - GTP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0016787 - hydrolase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1307354

ZNG1B
Zinc-regulated GTPase metalloprotein activator 1B

3

3

High-throughput

0.861

High

1196355

ZNG1F
Zinc-regulated GTPase metalloprotein activator 1F

3

3

High-throughput

0.847

High

921392

MAP11
Methionine aminopeptidase 1

4

3

High-throughput

0.694

High

163824

TCRG1
Transcription elongation regulator 1

3

1

High-throughput

0.667

High

547196

PYC
Pyruvate carboxylase, mitochondrial

3

1

High-throughput

0.667

High

896445

ERF
ETS domain-containing transcription factor ERF

3

6

High-throughput

0.667

High

909165

NEK4
Serine/threonine-protein kinase Nek4

3

1

High-throughput

0.667

High

981945

RL23
Large ribosomal subunit protein uL14

3

1

High-throughput

0.667

High

1191954

TBB8
Tubulin beta-8 chain

3

2

High-throughput

0.667

High

1333229

DTWD2
tRNA-uridine aminocarboxypropyltransferase 2

3

1

High-throughput

0.667

High

1356865

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

3

1

High-throughput

0.667

High

1411836

EGLN1
Egl nine homolog 1

3

1

High-throughput

0.667

High

1411859

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

3

2

High-throughput

0.656

High

1247627

SAMD1
Sterile alpha motif domain-containing protein 1

3

0

High-throughput

0.638

High

1334406

UXS1
UDP-glucuronic acid decarboxylase 1

3

0

High-throughput

0.638

High

1411855

TRM6
tRNA

3

0

High-throughput

0.638

High

366259

FA9
Coagulation factor IX

2

1

High-throughput

0.628

High

212991

HS12A
Heat shock 70 kDa protein 12A

2

2

High-throughput

0.611

High

1180070

PWP3A
PWWP domain-containing DNA repair factor 3A

2

1

High-throughput

0.611

High

841578

I12R1
Interleukin-12 receptor subunit beta-1

3

1

High-throughput

0.609

High

1129977

MELK
Maternal embryonic leucine zipper kinase

3

1

High-throughput

0.609

High

1411852

KLK11
Kallikrein-11

3

10

High-throughput

0.609

High

1411862

KLK5
Kallikrein-5

3

6

High-throughput

0.609

High

1388490

ZMY19
Zinc finger MYND domain-containing protein 19

2

3

High-throughput

0.606

High

1260496

BRNP3
BMP/retinoic acid-inducible neural-specific protein 3

2

0

High-throughput

0.602

High

290381

RFPL2
Ret finger protein-like 2

2

0

High-throughput

0.585

High

1411847

RTEL1
Regulator of telomere elongation helicase 1

2

0

High-throughput

0.585

High

1411858

TTF2
Transcription termination factor 2

2

0

High-throughput

0.585

High

1408097

SSX3
Protein SSX3

2

0

High-throughput

0.580

High

142230

CCL22
C-C motif chemokine 22

2

1

High-throughput

0.574

High

1101303

SLAF1
Signaling lymphocytic activation molecule

2

2

High-throughput

0.574

High

1248313

SFTA2
Surfactant-associated protein 2

2

1

High-throughput

0.574

High

1324271

LYPD1
Ly6/PLAUR domain-containing protein 1

2

1

High-throughput

0.574

High

1349101

F174A
Membrane protein FAM174A

2

2

High-throughput

0.574

High

1381160

SNX21
Sorting nexin-21

2

2

High-throughput

0.574

High

1411856

DKKL1
Dickkopf-like protein 1

2

2

High-throughput

0.574

High

622476

ELK1
ETS domain-containing protein Elk-1

2

6

High-throughput

0.571

High

1398228

HS12B
Heat shock 70 kDa protein 12B

2

2

High-throughput

0.558

High

1411842

KLK15
Kallikrein-15

2

9

High-throughput

0.558

High

158494

RFXK
DNA-binding protein RFXANK

1

2

High-throughput

0.536

High

259074

DNJA2
DnaJ homolog subfamily A member 2

1

2

High-throughput

0.536

High

261547

B4GT2
Beta-1,4-galactosyltransferase 2

1

1

High-throughput

0.536

High

370043

CYTC
Cystatin-C

1

1

High-throughput

0.536

High

457654

TBB5
Tubulin beta chain

1

2

High-throughput

0.536

High

1006295

CTG1B
Cancer/testis antigen 1

1

1

High-throughput

0.536

High

1108683

TBB3
Tubulin beta-3 chain

1

2

High-throughput

0.536

High

1111484

IQGA2
Ras GTPase-activating-like protein IQGAP2

1

2

High-throughput

0.536

High

1148025

SF3B3
Splicing factor 3B subunit 3

1

1

High-throughput

0.536

High

1316624

CDK20
Cyclin-dependent kinase 20

1

1

High-throughput

0.536

High

1359075

SPRY4
SPRY domain-containing protein 4

1

1

High-throughput

0.536

High

1406974

NPAS1
Neuronal PAS domain-containing protein 1

1

1

High-throughput

0.536

High

1411838

CLPB
Mitochondrial disaggregase

1

1

High-throughput

0.536

High

1411853

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

4

High-throughput

0.536

High

1411863

C2CD2
C2 domain-containing protein 2

1

1

High-throughput

0.536

High

1411864

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

1

High-throughput

0.536

High

1411849

KLRF1
Killer cell lectin-like receptor subfamily F member 1

2

4

High-throughput

0.533

High

134848

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.513

High

275360

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

1

0

High-throughput

0.513

High

288255

KBL
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial

1

0

High-throughput

0.513

High

377003

ANF
Natriuretic peptides A

1

0

High-throughput

0.513

High

486608

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

574059

HXB1
Homeobox protein Hox-B1

1

0

High-throughput

0.513

High

593481

PGFRA
Platelet-derived growth factor receptor alpha

1

0

High-throughput

0.513

High

774797

TIMP3
Metalloproteinase inhibitor 3

1

0

High-throughput

0.513

High

937185

ADK
Adenosine kinase

1

0

High-throughput

0.513

High

941834

ARL4C
ADP-ribosylation factor-like protein 4C

1

0

High-throughput

0.513

High

952693

PROF3
Profilin-3

1

0

High-throughput

0.513

High

1279279

PODN
Podocan

1

0

High-throughput

0.513

High

1310351

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1329839

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

High-throughput

0.513

High

1331300

ENDOV
Endonuclease V

1

0

High-throughput

0.513

High

1350324

MK15
Mitogen-activated protein kinase 15

1

0

High-throughput

0.513

High

1398200

PPM1M
Protein phosphatase 1M

1

0

High-throughput

0.513

High

1400383

PUS7
Pseudouridylate synthase 7 homolog

1

0

High-throughput

0.513

High

1411832

BEX2
Protein BEX2

1

0

High-throughput

0.513

High

1411834

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

1411843

SENP3
Sentrin-specific protease 3

1

0

High-throughput

0.513

High

1411844

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

0

High-throughput

0.513

High

1411846

SPNXB
Sperm protein associated with the nucleus on the X chromosome B1

1

0

High-throughput

0.513

High

282622

ERN1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

High-throughput

0.493

High

370767

FOS
Protein c-Fos

1

0

High-throughput

0.493

High

728817

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

0

High-throughput

0.493

High

987908

GRB2
Growth factor receptor-bound protein 2

1

0

High-throughput

0.493

High

231060

VEGFD
Vascular endothelial growth factor D

1

3

High-throughput

0.489

High

369271

ANT3
Antithrombin-III

1

2

High-throughput

0.489

High

570713

EDN3
Endothelin-3

1

1

High-throughput

0.489

High

598273

CL3L1
C-C motif chemokine 3-like 1

1

1

High-throughput

0.489

High

634799

GRAH
Granzyme H

1

4

High-throughput

0.489

High

1204502

VWA2
von Willebrand factor A domain-containing protein 2

1

1

High-throughput

0.489

High

1310022

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

1

1

High-throughput

0.489

High

1334452

RELL2
RELT-like protein 2

1

1

High-throughput

0.489

High

1337453

FA83F
Protein FAM83F

1

1

High-throughput

0.489

High

1363131

CLC2B
C-type lectin domain family 2 member B

1

3

High-throughput

0.489

High

219091

RA51C
DNA repair protein RAD51 homolog 3

1

1

High-throughput

0.479

High

1005822

RPP30
Ribonuclease P protein subunit p30

1

1

High-throughput

0.479

High

1114141

CUL3
Cullin-3

1

1

High-throughput

0.479

High

1161376

HIF1A
Hypoxia-inducible factor 1-alpha

1

1

High-throughput

0.479

High

1255284

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

1259460

TBA1A
Tubulin alpha-1A chain

1

1

High-throughput

0.479

High

1361632

SSH1
Protein phosphatase Slingshot homolog 1

1

1

High-throughput

0.479

High

1369623

APBB2
Amyloid beta precursor protein binding family B member 2

1

2

High-throughput

0.479

High

1397370

CI072
Guanine nucleotide exchange factor C9orf72

1

4

High-throughput

0.479

High

242744

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

376900

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.458

High

840779

RS27
Small ribosomal subunit protein eS27

1

0

High-throughput

0.458

High

1141601

OZF
Zinc finger protein OZF

1

0

High-throughput

0.458

High

1215012

INT11
Integrator complex subunit 11

1

0

High-throughput

0.458

High

1275489

TRM1L
tRNA

1

0

High-throughput

0.458

High

1350245

DC2L1
Cytoplasmic dynein 2 light intermediate chain 1

1

0

High-throughput

0.458

High

1411837

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

1411839

DDX47
Probable ATP-dependent RNA helicase DDX47

1

0

High-throughput

0.458

High

1411848

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

95989

E7EUN2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

2

High-throughput

0.445

High

564294

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.445

High

1178342

CL16A
Protein CLEC16A

1

4

High-throughput

0.437

High

1194623

DUS28
Dual specificity phosphatase 28

1

1

High-throughput

0.437

High

1290478

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

2

High-throughput

0.437

High

1411854

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.426

High

1195473

Q4KN05
KLRF1 protein

1

1

High-throughput

0.407

High

1335695

MOT11
Monocarboxylate transporter 11

1

1

High-throughput

0.407

High

649903

ADRO
NADPH:adrenodoxin oxidoreductase, mitochondrial

3

0

High-throughput

0.347

High

1397315

CB048
Putative uncharacterized protein C2orf48

3

0

High-throughput

0.347

High

427935

ICAM1
Intercellular adhesion molecule 1

2

0

High-throughput

0.328

High

1324672

MUC20
Mucin-20

2

0

High-throughput

0.328

High

1396441

F167A
Protein FAM167A

2

0

High-throughput

0.328

High

342459

RPP29
Ribonuclease P protein subunit p29

2

0

High-throughput

0.318

High

597009

TSHR
Thyrotropin receptor

2

0

High-throughput

0.318

High

1147742

MTFR1
Mitochondrial fission regulator 1

2

0

High-throughput

0.318

High

1290265

Q86V94
LOC554223 protein

2

0

High-throughput

0.318

High

1403678

GPHA2
Glycoprotein hormone alpha-2

2

0

High-throughput

0.318

High

1411845

XAGE1
X antigen family member 1

2

0

High-throughput

0.313

High

64381

CDHR4
Cadherin-related family member 4

1

0

High-throughput

0.279

Low

64901

RCCD1
RCC1 domain-containing protein 1

1

0

High-throughput

0.279

Low

183719

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.279

Low

298220

DCTN3
Dynactin subunit 3

1

0

High-throughput

0.279

Low

327082

NXPH3
Neurexophilin-3

1

0

High-throughput

0.279

Low

333509

MPZL1
Myelin protein zero-like protein 1

1

0

High-throughput

0.279

Low

388737

C1QB
Complement C1q subcomponent subunit B

1

0

High-throughput

0.279

Low

409607

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

0

High-throughput

0.279

Low

549872

CD79A
B-cell antigen receptor complex-associated protein alpha chain

1

0

High-throughput

0.279

Low

946361

FAM3B
Protein FAM3B

1

0

High-throughput

0.279

Low

1025948

NDP
Norrin

1

0

High-throughput

0.279

Low

1091900

NPRL3
GATOR1 complex protein NPRL3

1

0

High-throughput

0.279

Low

1158273

RM23
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.279

Low

1192093

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

0

High-throughput

0.279

Low

1194706

GXLT1
Glucoside xylosyltransferase 1

1

0

High-throughput

0.279

Low

1242363

PLBL1
Phospholipase B-like 1

1

0

High-throughput

0.279

Low

1245328

WDR59
GATOR2 complex protein WDR59

1

0

High-throughput

0.279

Low

1248791

LYZL1
Lysozyme-like protein 1

1

0

High-throughput

0.279

Low

1254127

INSY2
Inhibitory synaptic factor 2A

1

0

High-throughput

0.279

Low

1279822

BTLA
B- and T-lymphocyte attenuator

1

0

High-throughput

0.279

Low

1291672

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.279

Low

1292668

PRSR2
Proline and serine-rich protein 2

1

0

High-throughput

0.279

Low

1293655

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.279

Low

1295028

TMM25
Transmembrane protein 25

1

0

High-throughput

0.279

Low

1316057

TRM2A
tRNA

1

0

High-throughput

0.279

Low

1338048

WFD11
Protein WFDC11

1

0

High-throughput

0.279

Low

1350871

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

1360039

OIT3
Oncoprotein-induced transcript 3 protein

1

0

High-throughput

0.279

Low

1362524

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

1

0

High-throughput

0.279

Low

1390341

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.279

Low

1411833

SCOT2
Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial

1

0

High-throughput

0.279

Low

1411835

LRC27
Leucine-rich repeat-containing protein 27

1

0

High-throughput

0.279

Low

1411840

SIRPD
Signal-regulatory protein delta

1

0

High-throughput

0.279

Low

1411841

IL25
Interleukin-25

1

0

High-throughput

0.279

Low

1411851

P2RX2
P2X purinoceptor 2

1

0

High-throughput

0.279

Low

1411860

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

0

High-throughput

0.279

Low

1411861

RT17
Small ribosomal subunit protein uS17m

1

0

High-throughput

0.279

Low

1081562

Q0VDC6
peptidylprolyl isomerase

1

0

High-throughput

0.268

Low

1357202

BRK1
Protein BRICK1

1

0

High-throughput

0.268

Low

873750

GSH0
Glutamate--cysteine ligase regulatory subunit

1

0

High-throughput

0.249

Low

894488

PPOX
Protoporphyrinogen oxidase

1

0

High-throughput

0.249

Low

903773

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.249

Low

1005763

RPP38
Ribonuclease P protein subunit p38

1

0

High-throughput

0.249

Low

1209040

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.249

Low

1240324

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

0

High-throughput

0.249

Low

1324168

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.249

Low

1324511

FA43A
Protein FAM43A

1

0

High-throughput

0.249

Low

1395568

SRAC1
Protein SERAC1

1

0

High-throughput

0.249

Low

1411850

CNIH4
Protein cornichon homolog 4

1

0

High-throughput

0.249

Low

1411857

APC10
Anaphase-promoting complex subunit 10

1

0

High-throughput

0.249

Low

231628

PRKY
Putative serine/threonine-protein kinase PRKY

1

0

High-throughput

0.232

Low

379167

TRAC
T cell receptor alpha chain constant

1

0

High-throughput

0.232

Low

634975

NTF3
Neurotrophin-3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025