Protein: PPIL1
Peptidyl-prolyl cis-trans isomerase-like 1 (PPIase) (EC 5.2.1.8) (Rotamase PPIL1)

Gene: PPIL1
Organism: Homo sapiens
Interactions: 110
UniProt ID: Q9Y3C6

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0000413 - protein peptidyl-prolyl isomerization
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1084675

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

2

2

High-throughput

0.831

High

1054698

RBM39
RNA-binding protein 39

2

3

High-throughput

0.789

High

1039962

SNW1
SNW domain-containing protein 1

7

3

Small-scale

0.754

High

1159354

PRP8
Pre-mRNA-processing-splicing factor 8

2

5

High-throughput

0.754

High

236146

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

1

High-throughput

0.691

High

446849

SNRPA
U1 small nuclear ribonucleoprotein A

1

3

High-throughput

0.691

High

641991

U2AF2
Splicing factor U2AF 65 kDa subunit

1

6

High-throughput

0.691

High

727109

FUS
RNA-binding protein FUS

1

5

High-throughput

0.691

High

1347102

RBM22
Pre-mRNA-splicing factor RBM22

1

1

High-throughput

0.691

High

1357567

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

3

High-throughput

0.691

High

453724

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

1

High-throughput

0.656

High

1312106

RBM42
RNA-binding protein 42

1

5

High-throughput

0.656

High

1356969

ISY1
Pre-mRNA-splicing factor ISY1 homolog

1

0

High-throughput

0.656

High

551327

ITF2
Transcription factor 4

3

0

High-throughput

0.646

High

1310834

WDR83
WD repeat domain-containing protein 83

2

4

High-throughput

0.644

High

967528

EWS
RNA-binding protein EWS

1

4

High-throughput

0.618

High

1303883

CDC5L
Cell division cycle 5-like protein

2

4

High-throughput

0.611

High

839852

LHX2
LIM/homeobox protein Lhx2

2

1

High-throughput

0.606

High

944110

PO6F2
POU domain, class 6, transcription factor 2

2

1

High-throughput

0.606

High

1271144

N42L2
NEDD4-binding protein 2-like 2

2

1

High-throughput

0.606

High

1377510

DEOC
Deoxyribose-phosphate aldolase

2

0

High-throughput

0.602

High

1221241

GPAM1
GPALPP motifs-containing protein 1

2

2

High-throughput

0.574

High

943036

SRPK2
SRSF protein kinase 2

1

4

High-throughput

0.569

High

1302110

SRPK1
SRSF protein kinase 1

1

4

High-throughput

0.569

High

1357293

COHA1
Collagen alpha-1(XVII) chain

2

1

High-throughput

0.553

High

1354665

RIM3A
RIMS-binding protein 3A

1

0

High-throughput

0.549

High

230821

AQR
RNA helicase aquarius

1

1

High-throughput

0.536

High

236270

PRP17
Pre-mRNA-processing factor 17

1

3

High-throughput

0.536

High

448863

RU1C
U1 small nuclear ribonucleoprotein C

1

2

High-throughput

0.536

High

508785

TOP1
DNA topoisomerase 1

1

3

High-throughput

0.536

High

539199

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

3

High-throughput

0.536

High

782187

BUD31
Protein BUD31 homolog

1

3

High-throughput

0.536

High

801477

KI67
Proliferation marker protein Ki-67

1

4

High-throughput

0.536

High

912004

RUXF
Small nuclear ribonucleoprotein F

1

7

High-throughput

0.536

High

996974

SSRP1
FACT complex subunit SSRP1

1

4

High-throughput

0.536

High

1074276

SF3A1
Splicing factor 3A subunit 1

1

2

High-throughput

0.536

High

1103283

C19L2
CWF19-like protein 2

1

1

High-throughput

0.536

High

1148623

C19L1
CWF19-like protein 1

1

1

High-throughput

0.536

High

1310470

GPTC1
G patch domain-containing protein 1

1

1

High-throughput

0.536

High

1318168

CRNL1
Crooked neck-like protein 1

1

4

High-throughput

0.536

High

1332153

DHX35
Probable ATP-dependent RNA helicase DHX35

1

1

High-throughput

0.536

High

1336502

SYF1
Pre-mRNA-splicing factor SYF1

1

4

High-throughput

0.536

High

1353903

TFP11
Tuftelin-interacting protein 11

1

1

High-throughput

0.536

High

581899

VCAM1
Vascular cell adhesion protein 1

2

2

High-throughput

0.521

High

1130755

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

5

High-throughput

0.521

High

268912

SF3B1
Splicing factor 3B subunit 1

1

0

High-throughput

0.513

High

278572

SPF27
Pre-mRNA-splicing factor SPF27

1

0

High-throughput

0.513

High

327825

SYF2
Pre-mRNA-splicing factor SYF2

1

0

High-throughput

0.513

High

558548

GCFC2
Intron Large complex component GCFC2

1

0

High-throughput

0.513

High

1260037

CCD12
Coiled-coil domain-containing protein 12

1

0

High-throughput

0.513

High

1290255

SAAL1
Protein SAAL1

1

0

High-throughput

0.513

High

1349489

CWC15
Spliceosome-associated protein CWC15 homolog

1

0

High-throughput

0.513

High

1232924

LNX2
Ligand of Numb protein X 2

1

5

High-throughput

0.512

High

1021784

PP1R8
Nuclear inhibitor of protein phosphatase 1

1

1

High-throughput

0.508

High

1309322

MEP50
Methylosome protein WDR77

1

2

High-throughput

0.508

High

1045295

THOC5
THO complex subunit 5 homolog

1

0

High-throughput

0.486

High

1073195

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.486

High

1312972

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

0

High-throughput

0.486

High

309888

GA45G
Growth arrest and DNA damage-inducible protein GADD45 gamma

1

0

High-throughput

0.480

High

123117

MEN1
Menin

1

2

High-throughput

0.479

High

210388

PRC1
Protein regulator of cytokinesis 1

1

1

High-throughput

0.479

High

348317

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.479

High

360570

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

4

High-throughput

0.479

High

375135

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

High-throughput

0.479

High

380054

MYCN
N-myc proto-oncogene protein

1

7

High-throughput

0.479

High

554123

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

652682

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

718349

BMI1
Polycomb complex protein BMI-1

1

2

High-throughput

0.479

High

721851

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.479

High

780366

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

801983

RECQ1
ATP-dependent DNA helicase Q1

1

2

High-throughput

0.479

High

824571

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.479

High

831835

CEBPA
CCAAT/enhancer-binding protein alpha

1

6

High-throughput

0.479

High

877973

FOXA1
Hepatocyte nuclear factor 3-alpha

1

1

High-throughput

0.479

High

909375

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

935415

H31
Histone H3.1

1

3

High-throughput

0.479

High

1026595

RFA4
Replication protein A 30 kDa subunit

1

4

High-throughput

0.479

High

1066923

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

1189085

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

1222882

SRRM1
Serine/arginine repetitive matrix protein 1

1

2

High-throughput

0.479

High

1251092

SNIP1
Smad nuclear-interacting protein 1

1

1

High-throughput

0.479

High

1256502

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

1270002

ESR2
Estrogen receptor beta

1

14

High-throughput

0.479

High

1272724

CSN5
COP9 signalosome complex subunit 5

1

3

High-throughput

0.479

High

1315415

KLF16
Krueppel-like factor 16

1

1

High-throughput

0.479

High

1315919

FACD2
Fanconi anemia group D2 protein

1

1

High-throughput

0.479

High

1354961

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1357217

FZR1
Fizzy-related protein homolog

1

3

High-throughput

0.479

High

1357829

SRRM2
Serine/arginine repetitive matrix protein 2

1

2

High-throughput

0.479

High

1377520

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

6

High-throughput

0.479

High

1377644

TRRAP
Transformation/transcription domain-associated protein

1

2

High-throughput

0.479

High

1377645

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

6

High-throughput

0.479

High

298915

UFL1
E3 UFM1-protein ligase 1

1

0

Small-scale

0.460

High

1153984

IFIX
Pyrin and HIN domain-containing protein 1

1

0

High-throughput

0.458

High

1304839

TBX5
T-box transcription factor TBX5

1

0

High-throughput

0.458

High

321258

PTBP3
Polypyrimidine tract-binding protein 3

1

1

High-throughput

0.445

High

497861

TAU
Microtubule-associated protein tau

1

6

High-throughput

0.445

High

1124668

ODFP2
Outer dense fiber protein 2

1

1

High-throughput

0.445

High

323350

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.437

High

363363

FINC
Fibronectin

1

2

High-throughput

0.437

High

530773

ITA4
Integrin alpha-4

1

1

High-throughput

0.437

High

1172386

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

1201794

ZCH18
Zinc finger CCCH domain-containing protein 18

1

6

High-throughput

0.437

High

64034

SPDE4
Speedy protein E4

2

0

High-throughput

0.316

High

474651

PRR35
Proline-rich protein 35

2

0

High-throughput

0.316

High

1134452

KPRP
Keratinocyte proline-rich protein

2

0

High-throughput

0.316

High

1287696

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.316

High

1290826

SAT2
Thialysine N-epsilon-acetyltransferase

1

0

High-throughput

0.279

Low

1224043

PRR22
Proline-rich protein 22

1

0

High-throughput

0.251

Low

1287598

GCP3
Gamma-tubulin complex component 3

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024