HitPredict

Interactor 1: DDI1 (Q8WTU0)
Protein DDI1 homolog 1 (EC 3.4.23.-)
Gene: DDI1

Interactor 2: NRIP3 (Q9NQ35)
Nuclear receptor-interacting protein 3 (Sarcoma antigen NY-SAR-105)
Gene: NRIP3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.895

Property	Details
Experiments	32839439, 26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Asp_protease~Asp_protease
Common GO terms	GO:0004190 - aspartic-type endopeptidase activity
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 396 Hs			1 241
+	Hs
		1136655 DDI2_HUMAN (1-392): 2.76e-155: 445: 70.93		NRIP3_HUMAN (1-241): 4.08e-111: 320: 100.00
+	Hs
		1259544 DDI1_HUMAN (1-396): 4.1e-163: 465: 100.00		DDI1_HUMAN (61-240): 1.69e-73: 230: 20.94
+	Hs
		1136633 DDI1_HUMAN (1-396): 4.1e-163: 465: 100.00		DDI2_HUMAN (56-234): 1.15e-71: 225: 20.00
+	Hs
		1136623 DDI2_HUMAN (1-392): 2.76e-155: 445: 70.93		DDI2_HUMAN (56-234): 1.15e-71: 225: 20.00
+	Dm
		1375389 Q9VXF9_DROME (5-395): 3.91e-131: 386: 47.58		Q9VXF9_DROME (61-240): 2.34e-67: 216: 18.33
+	Sc
		768183 DDI1_YEAST (14-369): 1.01e-91: 284: 29.41		DDI1_YEAST (53-226): 2.29e-60: 197: 21.51
+	Hs
		1136657 UBQL2_HUMAN (5-249): 4.55e-46: 168: 14.74		DDI2_HUMAN (56-234): 1.15e-71: 225: 20.00
+	Zm
		80385 B6TNT9_MAIZE (4-249): 2.98e-49: 176: 17.46		K7UR93_MAIZE (56-229): 2.31e-64: 207: 19.66
+	Dm
		1362834 Q9VCD5_DROME (5-218): 1.23e-30: 120: 18.92		Q9VXF9_DROME (61-240): 2.34e-67: 216: 18.33
+	Hs
		803572 BAG6_HUMAN (4-168): 1.28e-24: 108: 15.25		DDI2_HUMAN (56-234): 1.15e-71: 225: 20.00