Protein: K1C27
Keratin, type I cytoskeletal 27 (Cytokeratin-27) (CK-27) (Keratin-25C) (K25C) (Keratin-27) (K27) (Type I inner root sheath-specific keratin-K25irs3)

Gene: K1C27, KRT27
Organism: Homo sapiens
Interactions: 200
UniProt ID: Q7Z3Y8

Gene Ontology (top 5):
GO:0005198 - structural molecule activity
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005882 - intermediate filament
GO:0030855 - epithelial cell differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1021025

BFSP1
Filensin

3

20

High-throughput

0.858

High

213964

KRT86
Keratin, type II cuticular Hb6

2

20

High-throughput

0.783

High

318830

K2C75
Keratin, type II cytoskeletal 75

2

20

High-throughput

0.783

High

359510

K2C6A
Keratin, type II cytoskeletal 6A

2

20

High-throughput

0.783

High

380495

K2C6B
Keratin, type II cytoskeletal 6B

2

20

High-throughput

0.783

High

380646

K2C1
Keratin, type II cytoskeletal 1

2

20

High-throughput

0.783

High

409135

K2C8
Keratin, type II cytoskeletal 8

2

20

High-throughput

0.783

High

517765

K2C3
Keratin, type II cytoskeletal 3

2

20

High-throughput

0.783

High

531597

K2C5
Keratin, type II cytoskeletal 5

2

20

High-throughput

0.783

High

535447

GFAP
Glial fibrillary acidic protein

2

20

High-throughput

0.783

High

729033

K1C20
Keratin, type I cytoskeletal 20

2

20

High-throughput

0.783

High

729128

K22E
Keratin, type II cytoskeletal 2 epidermal

2

20

High-throughput

0.783

High

781928

PERI
Peripherin

2

20

High-throughput

0.783

High

821673

K2C6C
Keratin, type II cytoskeletal 6C

2

20

High-throughput

0.783

High

943646

KRT83
Keratin, type II cuticular Hb3

2

20

High-throughput

0.783

High

943682

KRT85
Keratin, type II cuticular Hb5

2

20

High-throughput

0.783

High

965442

K22O
Keratin, type II cytoskeletal 2 oral

2

20

High-throughput

0.783

High

1037518

BFSP2
Phakinin

2

19

High-throughput

0.783

High

1055212

KRT81
Keratin, type II cuticular Hb1

2

20

High-throughput

0.783

High

1062056

K2C72
Keratin, type II cytoskeletal 72

2

20

High-throughput

0.783

High

1110337

K2C71
Keratin, type II cytoskeletal 71

2

20

High-throughput

0.783

High

1140435

K2C79
Keratin, type II cytoskeletal 79

2

20

High-throughput

0.783

High

1186161

K2C74
Keratin, type II cytoskeletal 74

2

20

High-throughput

0.783

High

1189590

K2C1B
Keratin, type II cytoskeletal 1b

2

20

High-throughput

0.783

High

1189597

K2C78
Keratin, type II cytoskeletal 78

2

20

High-throughput

0.783

High

1189665

KRT82
Keratin, type II cuticular Hb2

2

20

High-throughput

0.783

High

1033956

XRCC4
DNA repair protein XRCC4

2

0

High-throughput

0.742

High

422215

NFL
Neurofilament light polypeptide

1

20

High-throughput

0.691

High

422415

NFM
Neurofilament medium polypeptide

1

20

High-throughput

0.691

High

1081728

AINX
Alpha-internexin

1

20

High-throughput

0.691

High

1189662

SYNCI
Syncoilin

1

20

High-throughput

0.691

High

310966

SNAPN
SNARE-associated protein Snapin

3

8

High-throughput

0.665

High

330097

DRC4
Dynein regulatory complex subunit 4

3

4

High-throughput

0.665

High

770621

TXLNA
Alpha-taxilin

3

20

High-throughput

0.665

High

580140

K2C4
Keratin, type II cytoskeletal 4

1

20

High-throughput

0.665

High

980280

K1C17
Keratin, type I cytoskeletal 17

1

20

High-throughput

0.618

High

1189592

HOOK3
Protein Hook homolog 3

3

20

High-throughput

0.607

High

1189627

SGF29
SAGA-associated factor 29

3

7

High-throughput

0.607

High

155014

NDC80
Kinetochore protein NDC80 homolog

2

20

High-throughput

0.606

High

160063

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

19

High-throughput

0.606

High

241775

CCD22
Coiled-coil domain-containing protein 22

2

14

High-throughput

0.606

High

339261

MOS
Proto-oncogene serine/threonine-protein kinase mos

2

4

High-throughput

0.606

High

794021

MATR3
Matrin-3

2

4

High-throughput

0.606

High

862231

ARFP1
Arfaptin-1

2

3

High-throughput

0.606

High

880767

HDAC4
Histone deacetylase 4

2

18

High-throughput

0.606

High

907080

PRS8
26S proteasome regulatory subunit 8

2

5

High-throughput

0.606

High

1028182

GPS2
G protein pathway suppressor 2

2

2

High-throughput

0.606

High

1065228

JOS1
Josephin-1

2

2

High-throughput

0.606

High

1066033

ARHG6
Rho guanine nucleotide exchange factor 6

2

1

High-throughput

0.606

High

1133993

CFA58
Cilia- and flagella-associated protein 58

2

12

High-throughput

0.606

High

1157413

PPR18
Phostensin

2

7

High-throughput

0.606

High

1189593

RASL3
RAS protein activator like-3

2

1

High-throughput

0.606

High

1189596

CC146
Coiled-coil domain-containing protein 146

2

14

High-throughput

0.606

High

1189610

CCHCR
Coiled-coil alpha-helical rod protein 1

2

19

High-throughput

0.606

High

1189615

GOGA1
Golgin subfamily A member 1

2

4

High-throughput

0.606

High

1189631

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

1

High-throughput

0.606

High

1189635

MTMR9
Myotubularin-related protein 9

2

1

High-throughput

0.606

High

1189639

F110A
Protein FAM110A

2

4

High-throughput

0.606

High

1189657

PININ
Pinin

2

1

High-throughput

0.606

High

1189664

EXOS5
Exosome complex component RRP46

2

5

High-throughput

0.606

High

1189667

ABI2
Abl interactor 2

2

20

High-throughput

0.606

High

1189670

RCOR3
REST corepressor 3

2

6

High-throughput

0.606

High

1189676

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

20

High-throughput

0.606

High

1189678

SUFU
Suppressor of fused homolog

2

1

High-throughput

0.606

High

60601

VP37C
Vacuolar protein sorting-associated protein 37C

2

0

High-throughput

0.580

High

283277

S22A5
Organic cation/carnitine transporter 2

2

0

High-throughput

0.580

High

533607

TNNT1
Troponin T, slow skeletal muscle

2

0

High-throughput

0.580

High

1189644

DUS26
Dual specificity protein phosphatase 26

2

0

High-throughput

0.580

High

1189681

GSTK1
Glutathione S-transferase kappa 1

2

0

High-throughput

0.580

High

1189684

VATD
V-type proton ATPase subunit D

2

0

High-throughput

0.580

High

1117825

AARD
Alanine and arginine-rich domain-containing protein

2

1

High-throughput

0.561

High

60681

ODAD3
Outer dynein arm-docking complex subunit 3

2

9

High-throughput

0.553

High

180598

TEX28
Testis-specific protein TEX28

2

1

High-throughput

0.553

High

204364

MS18B
Protein Mis18-beta

2

9

High-throughput

0.553

High

246459

DTNB
Dystrobrevin beta

2

11

High-throughput

0.553

High

271125

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

2

15

High-throughput

0.553

High

278475

SPF27
Pre-mRNA-splicing factor SPF27

2

6

High-throughput

0.553

High

329169

F107A
Actin-associated protein FAM107A

2

2

High-throughput

0.553

High

495720

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

2

2

High-throughput

0.553

High

563789

ZNF3
Zinc finger protein 3

2

3

High-throughput

0.553

High

567861

HXB9
Homeobox protein Hox-B9

2

12

High-throughput

0.553

High

624459

CCNC
Cyclin-C

2

7

High-throughput

0.553

High

846611

ZNF80
Zinc finger protein 80

2

2

High-throughput

0.553

High

849779

SUOX
Sulfite oxidase, mitochondrial

2

2

High-throughput

0.553

High

987431

MTG8
Protein CBFA2T1

2

1

High-throughput

0.553

High

1062315

RTP5
Receptor-transporting protein 5

2

2

High-throughput

0.553

High

1075202

TEAD4
Transcriptional enhancer factor TEF-3

2

1

High-throughput

0.553

High

1103506

KLH38
Kelch-like protein 38

2

4

High-throughput

0.553

High

1133618

SKT
Sickle tail protein homolog

2

2

High-throughput

0.553

High

1139985

TTC23
Tetratricopeptide repeat protein 23

2

11

High-throughput

0.553

High

1144691

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

8

High-throughput

0.553

High

1148018

ZFY26
Zinc finger FYVE domain-containing protein 26

2

20

High-throughput

0.553

High

1162347

ZC3HE
Zinc finger CCCH domain-containing protein 14

2

1

High-throughput

0.553

High

1166621

CCBE1
Collagen and calcium-binding EGF domain-containing protein 1

2

2

High-throughput

0.553

High

1184420

TEDC2
Tubulin epsilon and delta complex protein 2

2

10

High-throughput

0.553

High

1188215

NUP54
Nucleoporin p54

2

1

High-throughput

0.553

High

1189591

EX3L1
Exocyst complex component 3-like protein

2

1

High-throughput

0.553

High

1189594

Q8IVT4
Hypothetical MGC50722

2

3

High-throughput

0.553

High

1189595

LMTD2
Lamin tail domain-containing protein 2

2

1

High-throughput

0.553

High

1189598

TXLNB
Beta-taxilin

2

20

High-throughput

0.553

High

1189599

USBP1
Harmonin-binding protein USHBP1

2

19

High-throughput

0.553

High

1189600

CC185
Coiled-coil domain-containing protein 185

2

9

High-throughput

0.553

High

1189601

TRIMM
Probable E3 ubiquitin-protein ligase TRIML2

2

13

High-throughput

0.553

High

1189602

MORN4
MORN repeat-containing protein 4

2

3

High-throughput

0.553

High

1189606

MB3L2
Methyl-CpG-binding domain protein 3-like 2

2

2

High-throughput

0.553

High

1189607

CA216
UPF0500 protein C1orf216

2

9

High-throughput

0.553

High

1189608

G45IP
Large ribosomal subunit protein mL64

2

1

High-throughput

0.553

High

1189609

SMRC2
SWI/SNF complex subunit SMARCC2

2

20

High-throughput

0.553

High

1189616

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

2

9

High-throughput

0.553

High

1189619

FAKD4
FAST kinase domain-containing protein 4

2

2

High-throughput

0.553

High

1189624

ZN669
Zinc finger protein 669

2

8

High-throughput

0.553

High

1189630

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

2

6

High-throughput

0.553

High

1189633

CC138
Coiled-coil domain-containing protein 138

2

1

High-throughput

0.553

High

1189637

THIOM
Thioredoxin, mitochondrial

2

4

High-throughput

0.553

High

1189642

THAP7
THAP domain-containing protein 7

2

4

High-throughput

0.553

High

1189646

NUP58
Nucleoporin p58/p45

2

1

High-throughput

0.553

High

1189647

SCNM1
Sodium channel modifier 1

2

4

High-throughput

0.553

High

1189648

BEX2
Protein BEX2

2

7

High-throughput

0.553

High

1189649

SEM4C
Semaphorin-4C

2

2

High-throughput

0.553

High

1189650

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

2

2

High-throughput

0.553

High

1189651

HPLN2
Hyaluronan and proteoglycan link protein 2

2

5

High-throughput

0.553

High

1189655

CCD68
Coiled-coil domain-containing protein 68

2

20

High-throughput

0.553

High

1189656

RNF39
RING finger protein 39

2

18

High-throughput

0.553

High

1189669

ZN581
Zinc finger protein 581

2

5

High-throughput

0.553

High

1189672

GBG13

2

2

High-throughput

0.553

High

1189673

DPOLL
DNA polymerase lambda

2

2

High-throughput

0.553

High

1189677

ZN580
Zinc finger protein 580

2

4

High-throughput

0.553

High

1189680

T3JAM
TRAF3-interacting JNK-activating modulator

2

9

High-throughput

0.553

High

1189682

WASC3
WASH complex subunit 3

2

3

High-throughput

0.553

High

1189683

PCDBE
Protocadherin beta-14

2

1

High-throughput

0.553

High

61865

CC88B
Coiled-coil domain-containing protein 88B

1

11

High-throughput

0.536

High

300922

HAUS5
HAUS augmin-like complex subunit 5

1

2

High-throughput

0.536

High

885266

EPIPL
Epiplakin

1

20

High-throughput

0.536

High

994761

GOGA3
Golgin subfamily A member 3

1

14

High-throughput

0.536

High

1041374

CUL2
Cullin-2

1

20

High-throughput

0.536

High

1068476

KPCD1
Serine/threonine-protein kinase D1

1

4

High-throughput

0.536

High

1146561

A16L1
Autophagy-related protein 16-1

1

8

High-throughput

0.536

High

1163344

BL1S2
Biogenesis of lysosome-related organelles complex 1 subunit 2

1

1

High-throughput

0.536

High

1189605

TNIP2
TNFAIP3-interacting protein 2

1

7

High-throughput

0.536

High

1189613

UBP33
Ubiquitin carboxyl-terminal hydrolase 33

1

14

High-throughput

0.536

High

1189614

TSC1
Hamartin

1

17

High-throughput

0.536

High

1189620

EXOC4
Exocyst complex component 4

1

5

High-throughput

0.536

High

1189625

HAUS1
HAUS augmin-like complex subunit 1

1

4

High-throughput

0.536

High

1189626

SPDLY
Protein Spindly

1

7

High-throughput

0.536

High

1189628

DTBP1
Dysbindin

1

1

High-throughput

0.536

High

1189636

SPAG5
Sperm-associated antigen 5

1

18

High-throughput

0.536

High

1189645

CP250
Centrosome-associated protein CEP250

1

8

High-throughput

0.536

High

1189653

ATG5
Autophagy protein 5

1

2

High-throughput

0.536

High

1189654

GAN
Gigaxonin

1

13

High-throughput

0.536

High

1189658

CENPH
Centromere protein H

1

1

High-throughput

0.536

High

1189660

HAUS4
HAUS augmin-like complex subunit 4

1

2

High-throughput

0.536

High

1189666

TXLNG
Gamma-taxilin

1

20

High-throughput

0.536

High

1189674

VPS51
Vacuolar protein sorting-associated protein 51 homolog

1

5

High-throughput

0.536

High

1169151

Q6ZN96
cDNA FLJ16308 fis, clone PUAEN2006335

1

1

High-throughput

0.515

High

344202

A1AT
Alpha-1-antitrypsin

1

0

High-throughput

0.513

High

873785

AIF1
Allograft inflammatory factor 1

1

0

High-throughput

0.513

High

944545

BL1S1
Biogenesis of lysosome-related organelles complex 1 subunit 1

1

0

High-throughput

0.513

High

1054288

NF2L1
Endoplasmic reticulum membrane sensor NFE2L1

1

0

High-throughput

0.513

High

1147714

HAUS3
HAUS augmin-like complex subunit 3

1

0

High-throughput

0.513

High

1189640

KLDC3
Kelch domain-containing protein 3

1

0

High-throughput

0.513

High

1189679

COG5
Conserved oligomeric Golgi complex subunit 5

1

0

High-throughput

0.513

High

1070132

RABE1
Rab GTPase-binding effector protein 1

1

5

High-throughput

0.489

High

1120241

CEP55
Centrosomal protein of 55 kDa

1

3

High-throughput

0.489

High

1164938

SAS6
Spindle assembly abnormal protein 6 homolog

1

20

High-throughput

0.489

High

1189137

CC186
Coiled-coil domain-containing protein 186

1

12

High-throughput

0.489

High

1189604

NAV1
Neuron navigator 1

1

3

High-throughput

0.489

High

1189623

PF21A
PHD finger protein 21A

1

20

High-throughput

0.489

High

1189641

KXDL1
KxDL motif-containing protein 1

1

3

High-throughput

0.489

High

1189671

CING
Cingulin

1

4

High-throughput

0.489

High

1118976

AMOT
Angiomotin

1

20

High-throughput

0.481

High

1189634

FMNL2
Formin-like protein 2

1

1

High-throughput

0.481

High

1116356

LARP7
La-related protein 7

1

16

High-throughput

0.479

High

1189663

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

14

High-throughput

0.479

High

57687

A2BDD9
AMOT protein

1

20

High-throughput

0.470

High

1012168

Q0VAL7
C21orf58 protein

1

5

High-throughput

0.470

High

1189621

Q96AL5
PBX3 protein

1

3

High-throughput

0.470

High

1189618

RAB24
Ras-related protein Rab-24

1

6

High-throughput

0.445

High

1189659

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

20

High-throughput

0.445

High

773183

PBX3
Pre-B-cell leukemia transcription factor 3

1

3

High-throughput

0.439

High

885748

CU058
Uncharacterized protein C21orf58

1

5

High-throughput

0.439

High

303332

HEXI1
Protein HEXIM1

1

20

High-throughput

0.437

High

1184180

MEPCE
7SK snRNA methylphosphate capping enzyme

1

15

High-throughput

0.437

High

1189652

RNF38
E3 ubiquitin-protein ligase RNF38

1

3

Small-scale

0.437

High

50863

SRCRL
Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D

2

0

High-throughput

0.316

High

62629

SDHF1
Succinate dehydrogenase assembly factor 1, mitochondrial

2

0

High-throughput

0.316

High

1167230

DPPA3
Developmental pluripotency-associated protein 3

2

0

High-throughput

0.316

High

1189603

ICA1L
Islet cell autoantigen 1-like protein

2

0

High-throughput

0.316

High

1189611

LKAM1
Protein LKAAEAR1

2

0

High-throughput

0.316

High

1189629

CEP95
Centrosomal protein of 95 kDa

2

0

High-throughput

0.316

High

1189632

RBM41
RNA-binding protein 41

2

0

High-throughput

0.316

High

1189638

SSX3
Protein SSX3

2

0

High-throughput

0.316

High

1189643

NDUF3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3

2

0

High-throughput

0.316

High

1189661

CS044
Uncharacterized protein C19orf44

2

0

High-throughput

0.316

High

1189675

TSKS
Testis-specific serine kinase substrate

2

0

High-throughput

0.316

High

263065

SPAG7
Sperm-associated antigen 7

1

0

High-throughput

0.279

Low

1134728

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.279

Low

1189612

BL1S5
Biogenesis of lysosome-related organelles complex 1 subunit 5

1

0

High-throughput

0.279

Low

1189617

BORC5
BLOC-1-related complex subunit 5

1

0

High-throughput

0.279

Low

1189622

BORC7
BLOC-1-related complex subunit 7

1

0

High-throughput

0.279

Low

1189668

HPBP1
Hsp70-binding protein 1

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024