HitPredict

Interactor 1: PDC6I (Q8WUM4)
Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (ALG-2-interacting protein X) (Hp95)
Gene: PDCD6IP

Interactor 2: CHM4B (Q9H444)
Charged multivesicular body protein 4b (Chromatin-modifying protein 4b) (CHMP4b) (SNF7 homolog associated with Alix 1) (SNF7-2) (hSnf7-2) (Vacuolar protein sorting-associated protein 32-2) (Vps32-2) (hVps32-2)
Gene: CHMP4B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.758

The method score is based on:

Property Details
Experiments 26496610, 26490116, 31586073, 14505570, 17174262, 20929444, 23895345, 21889351, 18511562, 22484091, 18434552
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, x-ray crystallography, fluorescence polarization spectroscopy, pull down, surface plasmon resonance
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000281 - mitotic cytokinesis
GO:0005768 - endosome
GO:0005829 - cytosol
GO:0010824 - regulation of centrosome duplication
GO:0015031 - protein transport
and 9 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 868
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024