HitPredict

Interactor 1: KBTB7 (Q8WVZ9)
Kelch repeat and BTB domain-containing protein 7
Gene: KBTBD7

Interactor 2: GBRL1 (Q9H0R8)
Gamma-aminobutyric acid receptor-associated protein-like 1 (Early estrogen-regulated protein) (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1)
Gene: GABARAPL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.896

Property	Details
Experiments	25684205, 25416956, 20562859
Identification Methods	affinity chromatography technology, two hybrid, pull down, unspecified method, validated two hybrid, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	ATG8~KBTB_W-LIR
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 684 Hs			1 117
+	Hs
		891243 KBTB7_HUMAN (1-684): 3.49e-171: 507: 100.00		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		306250 KBTB7_HUMAN (1-684): 3.49e-171: 507: 100.00		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Hs
		891206 KBTB6_HUMAN (1-674): 7.18e-160: 478: 89.76		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		1262059 KBTB7_HUMAN (1-684): 3.49e-171: 507: 100.00		MLP3C_HUMAN (5-116): 1.61e-44: 143: 39.47
+	Hs
		1201303 KBTB6_HUMAN (1-674): 7.18e-160: 478: 89.76		GBRL1_HUMAN (1-117): 4.54e-56: 171: 100.00
+	Hs
		306221 KBTB6_HUMAN (1-674): 7.18e-160: 478: 89.76		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Hs
		1262064 KBTB7_HUMAN (1-684): 3.49e-171: 507: 100.00		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		1201299 KBTB6_HUMAN (1-674): 7.18e-160: 478: 89.76		MLP3C_HUMAN (5-116): 1.61e-44: 143: 39.47
+	Hs
		1201302 KBTB6_HUMAN (1-674): 7.18e-160: 478: 89.76		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		891139 KEAP1_HUMAN (433-682): 2.89e-47: 178: 16.79		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		1049326 KEAP1_HUMAN (433-682): 2.89e-47: 178: 16.79		GBRL1_HUMAN (1-117): 4.54e-56: 171: 100.00
+	Hs
		306167 KEAP1_HUMAN (433-682): 2.89e-47: 178: 16.79		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Hs
		1049329 KEAP1_HUMAN (433-682): 2.89e-47: 178: 16.79		MLP3A_HUMAN (5-116): 1.09e-44: 142: 34.21
+	Hs
		1049322 KEAP1_HUMAN (433-682): 2.89e-47: 178: 16.79		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		891272 KLHL5_HUMAN (237-483): 3.89e-26: 116: 15.14		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Dm
		1181841 Q7KSF5_DROME (283-482): 2.08e-25: 114: 12.44		Q9W2S2_DROME (1-116): 1.56e-57: 175: 85.35
+	Hs
		1299556 KLHL5_HUMAN (237-483): 3.89e-26: 116: 15.14		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		1120814 KLH12_HUMAN (505-684): 3.93e-20: 96.5: 12.11		MLP3A_HUMAN (5-116): 1.09e-44: 142: 34.21
+	Hs
		1120811 KLH12_HUMAN (505-684): 3.93e-20: 96.5: 12.11		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62