HitPredict

Interactor 1: SYNE2 (Q8WXH0)
Nesprin-2 (KASH domain-containing protein 2) (KASH2) (Nuclear envelope spectrin repeat protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE) (Synaptic nuclear envelope protein 2) (Syne-2)
Gene: SYNE2

Interactor 2: NDEL1 (Q9GZM8)
Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin-associated protein 1)
Gene: NDEL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	unassigned1973
Identification Methods	two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0051642 - centrosome localization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 6885 Hs			1 345
+	Hs
		149115 SYNE2_HUMAN (1-6885): 0: 1508: 100.00		CTRO_HUMAN (12-211): 2.55e-24: 106: 19.32
+	Hs
		1329042 SPTN4_HUMAN (24-301): 1.87e-42: 176: 41.28		NDE1_HUMAN (3-321): 2.95e-41: 149: 55.25
+	Hs
		1244133 SYNE1_HUMAN (5226-6861): 2.45e-16: 90.3: 9.43		NDEL1_HUMAN (1-345): 1.8e-67: 217: 100.00
+	Hs
		809164 UTRN_HUMAN (5750-6838): 8.47e-16: 88.3: 10.19		NDEL1_HUMAN (1-345): 1.8e-67: 217: 100.00
+	Hs
		149428 MACF1_HUMAN (279-2502): 1.13e-48: 197: 10.79		CTRO_HUMAN (12-211): 2.55e-24: 106: 19.32
+	Hs
		725073 MACF1_HUMAN (279-2502): 1.13e-48: 197: 10.79		MYH9_HUMAN (2-223): 7.48e-24: 105: 17.57
+	Hs
		724786 DYST_HUMAN (282-2999): 6.47e-48: 195: 9.98		MYH9_HUMAN (2-223): 7.48e-24: 105: 17.57
+	Hs
		149277 SPTN4_HUMAN (24-301): 1.87e-42: 176: 41.28		CTRO_HUMAN (12-211): 2.55e-24: 106: 19.32
+	Hs
		148841 PLEC_HUMAN (4832-6877): 3.53e-41: 172: 10.20		CTRO_HUMAN (12-211): 2.55e-24: 106: 19.32
+	Mm
		93686 E9Q6R7_MOUSE (184-2832): 1.29e-23: 114: 10.21		NDE1_MOUSE (3-345): 7.34e-47: 164: 54.31
+	Hs
		724839 PLEC_HUMAN (4832-6877): 3.53e-41: 172: 10.20		MYH9_HUMAN (2-223): 7.48e-24: 105: 17.57
+	Hs
		1068649 PLEC_HUMAN (4832-6877): 3.53e-41: 172: 10.20		KIFC1_HUMAN (12-245): 7e-23: 101: 16.24
+	Mm
		513812 DMD_MOUSE (5522-6849): 6.94e-18: 95.3: 9.84		NDE1_MOUSE (3-345): 7.34e-47: 164: 54.31
+	Hs
		1068614 PLEC_HUMAN (4832-6877): 3.53e-41: 172: 10.20		CTTB2_HUMAN (1-342): 7.57e-11: 65.4: 13.50
+	Hs
		809187 UTRN_HUMAN (5750-6838): 8.47e-16: 88.3: 10.19		NDE1_HUMAN (3-321): 2.95e-41: 149: 55.25
+	Hs
		149072 SYNE1_HUMAN (5226-6861): 2.45e-16: 90.3: 9.43		CTRO_HUMAN (12-211): 2.55e-24: 106: 19.32
+	Hs
		148142 SPTN2_HUMAN (2344-4109): 4.77e-15: 86: 7.96		CTRO_HUMAN (12-211): 2.55e-24: 106: 19.32
+	Hs
		164575 SPTN2_HUMAN (2344-4109): 4.77e-15: 86: 7.96		MYH9_HUMAN (2-223): 7.48e-24: 105: 17.57
+	Hs
		110636 H3BPE1_HUMAN (5892-6861): 3.68e-14: 82.9: 10.89		MYH9_HUMAN (2-223): 7.48e-24: 105: 17.57
+	Hs
		148330 SPTB1_HUMAN (5680-6858): 6.17e-12: 75.6: 11.32		CTRO_HUMAN (12-211): 2.55e-24: 106: 19.32