HitPredict - High confidence protein-protein interactions

Interactor 1: DGCR8 (Q8WYQ5)
Microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8)
Gene: DGCR8

Interactor 2: DGCR8 (Q8WYQ5)
Microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8)
Gene: DGCR8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.90	0.716

Property	Details
Experiments	17159994, 15574589
Identification Methods	molecular sieving, anti tag coimmunoprecipitation
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	dsrm~dsrm
Common GO terms	GO:0003725 - double-stranded RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005737 - cytoplasm and 16 others more... GO:0005829 - cytosol GO:0006974 - DNA damage response GO:0014069 - postsynaptic density GO:0016604 - nuclear body GO:0020037 - heme binding GO:0030674 - protein-macromolecule adaptor activity GO:0031053 - primary miRNA processing GO:0035861 - site of double-strand break GO:0042803 - protein homodimerization activity GO:0046872 - metal ion binding GO:0070877 - microprocessor complex GO:0070878 - primary miRNA binding GO:0072091 - regulation of stem cell proliferation GO:0098978 - glutamatergic synapse GO:0140517 - protein-RNA adaptor activity GO:2000633 - positive regulation of pre-miRNA processing
Homologous interactions	0

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Last updated: 15 Jul 2024