Protein: CUP
Protein cup (Oskar ribonucleoprotein complex 147 kDa subunit)

Gene: CUP
Organism: Drosophila melanogaster
Interactions: 75
UniProt ID: Q9VMA3

Gene Ontology (top 5):
GO:0000932 - P-body
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

874941

IF4E
Eukaryotic translation initiation factor 4E1

10

1

Small-scale

0.978

High

654369

DDX6
ATP-dependent RNA helicase me31b

6

2

Small-scale

0.942

High

680650

NANOS
Protein nanos

4

0

Small-scale

0.660

High

1344376

Q8SYC0
Bruno 1, isoform D

2

2

Small-scale

0.620

High

1481655

Q9VTZ0
GH08269p

3

0

Small-scale

0.613

High

1481663

Q9W5B3
eIF-4F 25 kDa subunit

1

1

High-throughput

0.587

High

1171460

SMG
Protein Smaug

1

0

Small-scale

0.564

High

1476689

IF4A3
Eukaryotic initiation factor 4A-III

1

0

Small-scale

0.560

High

636422

PABP
Polyadenylate-binding protein

2

0

Small-scale

0.559

High

1377294

Q95RE4
LD37574p

2

0

Small-scale

0.559

High

669630

OSKA
Maternal effect protein oskar

1

0

Small-scale

0.529

High

1471859

Q9VDR7
Miranda, isoform A

1

0

Small-scale

0.529

High

51835

GUS
Protein gustavus

1

1

High-throughput

0.508

High

1470293

Q9VCD5
UV excision repair protein RAD23

1

1

High-throughput

0.508

High

195704

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.486

High

538276

HSP7D
Heat shock 70 kDa protein cognate 4

1

0

High-throughput

0.486

High

559169

RS26
Small ribosomal subunit protein eS26

1

0

High-throughput

0.486

High

898349

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.486

High

1174568

EXO1
Exonuclease 1

1

0

High-throughput

0.486

High

1264834

Q7K187
HL07962p

1

0

High-throughput

0.486

High

1467746

Q9VAC4
GEO09167p1

1

0

High-throughput

0.486

High

1469232

Q9VBJ6
Uncharacterized protein

1

0

High-throughput

0.486

High

1474106

Q9VFT4
AT27578p

1

0

High-throughput

0.486

High

1477334

Q9VID9
Uncharacterized protein, isoform B

1

0

High-throughput

0.486

High

1481653

INT15
Integrator complex subunit 15

1

0

High-throughput

0.486

High

118049

M9MS50
non-specific serine/threonine protein kinase

1

1

High-throughput

0.481

High

1481658

Q9VXG5
TNF-receptor-associated factor-like, isoform B

1

1

High-throughput

0.481

High

1064242

SQD
RNA-binding protein squid

1

1

Small-scale

0.479

High

1264617

Q7K126
CCR4-NOT transcription complex subunit 3

1

1

Small-scale

0.479

High

1303500

Q8IMZ2
Oo18 RNA-binding protein, isoform C

1

1

Small-scale

0.479

High

1375088

RGA
Regulator of gene activity

1

1

Small-scale

0.479

High

1481660

PGPLE
Peptidoglycan-recognition protein LE

1

1

High-throughput

0.479

High

682689

PUM
Maternal protein pumilio

1

0

Small-scale

0.460

High

1169494

Q1WWH6
RE42507p

1

0

Small-scale

0.460

High

95519

E2QCN4
Not1, isoform F

1

0

Small-scale

0.458

High

95564

E2QCZ3
Diamond

1

0

Small-scale

0.458

High

99348

F3YDK4
Purine-rich binding protein-alpha, isoform G

1

0

Small-scale

0.458

High

669656

STAU
Maternal effect protein staufen

1

0

Small-scale

0.458

High

705027

EXU
Maternal protein exuperantia

1

0

Small-scale

0.458

High

877819

RB27C
Heterogeneous nuclear ribonucleoprotein 27C

1

0

Small-scale

0.458

High

1171728

BICC
Protein bicaudal C

1

0

Small-scale

0.458

High

1173377

DIAP2
Death-associated inhibitor of apoptosis 2

1

0

High-throughput

0.458

High

1197206

RBP9X
Ran-binding proteins 9/10 homolog

1

0

Small-scale

0.458

High

1264596

Q7K112
poly(A)-specific ribonuclease

1

0

Small-scale

0.458

High

1374956

NFKB1
Nuclear factor NF-kappa-B p110 subunit

1

0

High-throughput

0.458

High

1428064

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.458

High

1464164

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.458

High

1473198

Q9VEV3
Tetratricopeptide repeat protein 1

1

0

High-throughput

0.458

High

1473384

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

0

High-throughput

0.458

High

1481661

Q9W1K4
Egalitarian, isoform B

1

0

High-throughput

0.458

High

1481665

X2JCC3
poly(A)-specific ribonuclease

1

0

Small-scale

0.458

High

197998

O18409
Testis-specific RNP-type RNA binding protein

1

2

Small-scale

0.457

High

1378996

Q960H6
LP08566p

1

1

High-throughput

0.457

High

1481652

Q9VNV0
non-specific serine/threonine protein kinase

1

1

High-throughput

0.457

High

1481662

Q9W481
LD15807p

1

1

High-throughput

0.457

High

1306648

Q8IRR4
GM27849p

1

1

High-throughput

0.439

High

1481666

X2JE21
Mind-meld, isoform J

1

1

High-throughput

0.439

High

1427724

PGPLC
Peptidoglycan-recognition protein LC

1

1

High-throughput

0.437

High

198183

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.426

High

909950

SRP
Box A-binding factor

1

0

High-throughput

0.426

High

1467313

Q9VA36
CIN85 and CD2AP related, isoform C

1

0

High-throughput

0.426

High

1480009

Q9VKX1
CCR4-NOT transcription complex subunit 4

1

0

High-throughput

0.426

High

1481654

Q9VSL8
Rhea, isoform B

1

0

High-throughput

0.426

High

1481657

Q9VWQ6
FI13061p

1

0

High-throughput

0.426

High

1481659

Q9VXL1
Mind-meld, isoform F

1

1

High-throughput

0.417

High

234885

O46070
EG:25E8.4 protein

1

0

High-throughput

0.265

Low

1019206

PDK
[Pyruvate dehydrogenase

1

0

High-throughput

0.265

Low

1344459

Q8SYG3
E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.265

Low

1481664

CHI10
Probable chitinase 10

1

0

High-throughput

0.265

Low

930477

CNN
Centrosomin

1

0

Small-scale

0.249

Low

1468658

Q9VAY2
Heat shock protein 83

1

0

Small-scale

0.249

Low

1481656

Q9VUK7
RE36140p

1

0

Small-scale

0.249

Low

305041

C3G
Guanine nucleotide-releasing factor 2

1

0

High-throughput

0.232

Low

1464410

Q9V3V3
protein-tyrosine-phosphatase

1

0

High-throughput

0.232

Low

1474898

Q9VGN4
Sarcomere length short, isoform B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025