HitPredict

Interactor 1: DGCR8 (Q8WYQ5)
Microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8)
Gene: DGCR8

Interactor 2: REPI1 (Q9BWE0)
Replication initiator 1 (60 kDa origin-specific DNA-binding protein) (60 kDa replication initiation region protein) (ATT-binding protein) (DHFR oribeta-binding protein RIP60) (Zinc finger protein 464)
Gene: REPIN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0046872 - metal ion binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 773 Hs			1 567
+	Hs
		1239544 DGCR8_HUMAN (1-773): 0: 1426: 100.00		ZFP62_HUMAN (2-172): 2.2e-56: 205: 21.64
+	Hs
		565096 DGCR8_HUMAN (1-773): 0: 1426: 100.00		ZNF7_HUMAN (393-567): 9.15e-42: 161: 47.43
+	Hs
		275744 DGCR8_HUMAN (1-773): 0: 1426: 100.00		ZN189_HUMAN (26-427): 1.19e-35: 143: 26.05
+	Hs
		1264683 DGCR8_HUMAN (1-773): 0: 1426: 100.00		ZN624_HUMAN (2-82): 2.55e-27: 118: 13.58