Interactor 1: DGCR8 (Q8WYQ5)
Microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8)
Gene: DGCR8

Interactor 2: RNC (Q9NRR4)
Ribonuclease 3 (EC 3.1.26.3) (Protein Drosha) (Ribonuclease III) (RNase III) (p241)
Gene: DROSHA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 26496610, 28514442, 33961781, 36950067, 17765891, 24778252, 35914814, 23995758, 22796965, 19626115, 15574589, 24581491, 22222205
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, molecular sieving
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains dsrm~dsrm, Ribonucleas_3_3~dsrm, Ribonuclease_3~dsrm
Common GO terms GO:0003725 - double-stranded RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005829 - cytosol
and 7 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 773
Hs

1 1374
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024