Protein: PSB10
Proteasome subunit beta type-10 (EC 3.4.25.1) (Low molecular mass protein 10) (Macropain subunit MECl-1) (Multicatalytic endopeptidase complex subunit MECl-1) (Proteasome MECl-1) (Proteasome subunit beta-2i)

Gene: PSB10, PSMB10
Organism: Homo sapiens
Interactions: 95
UniProt ID: P40306

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0000902 - cell morphogenesis
GO:0004175 - endopeptidase activity
GO:0004298 - threonine-type endopeptidase activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

822129

PSB3
Proteasome subunit beta type-3

5

20

Small-scale

0.922

High

681116

PSA2
Proteasome subunit alpha type-2

5

20

Small-scale

0.918

High

680800

PSA1
Proteasome subunit alpha type-1

5

20

Small-scale

0.914

High

822140

PSME1
Proteasome activator complex subunit 1

3

20

Small-scale

0.847

High

700843

PSB4
Proteasome subunit beta type-4

2

19

Small-scale

0.793

High

700499

PSB9
Proteasome subunit beta type-9

2

20

High-throughput

0.789

High

700571

PSA5
Proteasome subunit alpha type-5

2

20

High-throughput

0.776

High

332489

CCDB1
Cyclin-D1-binding protein 1

3

0

High-throughput

0.643

High

772653

MYH9
Myosin-9

2

2

High-throughput

0.628

High

681282

PSA3
Proteasome subunit alpha type-3

1

20

Small-scale

0.621

High

700439

PSB8
Proteasome subunit beta type-8

1

19

Small-scale

0.621

High

822173

POMP
Proteasome maturation protein

1

15

Small-scale

0.621

High

700992

PSB6
Proteasome subunit beta type-6

1

18

Small-scale

0.618

High

822145

PSME4
Proteasome activator complex subunit 4

1

11

Small-scale

0.618

High

822170

PSME2
Proteasome activator complex subunit 2

1

20

Small-scale

0.618

High

533891

IRF1
Interferon regulatory factor 1

2

9

Small-scale

0.584

High

822163

PSB7
Proteasome subunit beta type-7

1

20

Small-scale

0.575

High

209959

CRX
Cone-rod homeobox protein

1

1

High-throughput

0.573

High

822130

MEOX2
Homeobox protein MOX-2

1

2

High-throughput

0.573

High

175611

SR140
U2 snRNP-associated SURP motif-containing protein

1

2

High-throughput

0.536

High

348401

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

4

High-throughput

0.536

High

424805

ADT2
ADP/ATP translocase 2

1

2

High-throughput

0.536

High

482848

TPM1
Tropomyosin alpha-1 chain

1

3

High-throughput

0.536

High

532418

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.536

High

552151

ADT3
ADP/ATP translocase 3

1

2

High-throughput

0.536

High

671765

ZA2G
Zinc-alpha-2-glycoprotein

1

1

High-throughput

0.536

High

773116

MYH10
Myosin-10

1

2

High-throughput

0.536

High

822134

ARP2
Actin-related protein 2

1

2

High-throughput

0.536

High

822137

SRSF2
Serine/arginine-rich splicing factor 2

1

1

High-throughput

0.536

High

822155

MYH14
Myosin-14

1

2

High-throughput

0.536

High

822149

H31T
Histone H3.1t

1

2

High-throughput

0.515

High

240959

PRKN
E3 ubiquitin-protein ligase parkin

1

17

High-throughput

0.515

High

822175

RNF11
RING finger protein 11

1

11

High-throughput

0.515

High

351083

ECD
Protein ecdysoneless homolog

1

0

High-throughput

0.513

High

459872

APT
Adenine phosphoribosyltransferase

1

0

High-throughput

0.513

High

612535

RL7
Large ribosomal subunit protein uL30

1

0

High-throughput

0.513

High

701953

TMOD1
Tropomodulin-1

1

0

High-throughput

0.513

High

822131

CAZA1
F-actin-capping protein subunit alpha-1

1

0

High-throughput

0.513

High

822133

ACTB
Actin, cytoplasmic 1

1

0

High-throughput

0.513

High

822135

RL27
Large ribosomal subunit protein eL27

1

0

High-throughput

0.513

High

822141

FLII
Protein flightless-1 homolog

1

0

High-throughput

0.513

High

822146

UBX2B
UBX domain-containing protein 2B

1

0

High-throughput

0.513

High

822148

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

0

High-throughput

0.513

High

822152

NAA35
N-alpha-acetyltransferase 35, NatC auxiliary subunit

1

0

High-throughput

0.513

High

822161

PHF10
PHD finger protein 10

1

0

High-throughput

0.513

High

822164

NUP85
Nuclear pore complex protein Nup85

1

0

High-throughput

0.513

High

822168

BCCIP
BRCA2 and CDKN1A-interacting protein

1

0

High-throughput

0.513

High

822171

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.513

High

627931

ANXA7
Annexin A7

1

5

High-throughput

0.508

High

636711

PTN
Pleiotrophin

1

1

High-throughput

0.494

High

822156

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

156432

ACPM
Acyl carrier protein, mitochondrial

1

2

High-throughput

0.489

High

640572

MK
Midkine

1

1

High-throughput

0.489

High

651759

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

1

High-throughput

0.489

High

666258

THIL
Acetyl-CoA acetyltransferase, mitochondrial

1

2

High-throughput

0.489

High

680254

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

2

High-throughput

0.489

High

728742

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

1

High-throughput

0.489

High

822136

S25A3
Solute carrier family 25 member 3

1

3

High-throughput

0.489

High

822143

RBM39
RNA-binding protein 39

1

3

High-throughput

0.489

High

822144

ITPR3
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3

1

1

High-throughput

0.489

High

822153

HSDL2
Hydroxysteroid dehydrogenase-like protein 2

1

4

High-throughput

0.489

High

822158

CHERP
Calcium homeostasis endoplasmic reticulum protein

1

1

High-throughput

0.489

High

822159

CBR4
3-oxoacyl-[acyl-carrier-protein] reductase

1

3

High-throughput

0.489

High

822177

CD2AP
CD2-associated protein

1

2

High-throughput

0.489

High

822178

LRRF2
Leucine-rich repeat flightless-interacting protein 2

1

2

High-throughput

0.489

High

271957

OBSL1
Obscurin-like protein 1

1

6

High-throughput

0.479

High

289125

PRDM1
PR domain zinc finger protein 1

1

1

Small-scale

0.479

High

429443

JUN
Transcription factor Jun

1

7

High-throughput

0.479

High

571567

IRF2
Interferon regulatory factor 2

1

9

Small-scale

0.479

High

822132

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

3

High-throughput

0.479

High

822138

IRF8
Interferon regulatory factor 8

1

9

Small-scale

0.479

High

822139

TF65
Transcription factor p65

1

7

Small-scale

0.479

High

822142

TADBP
TAR DNA-binding protein 43

1

2

Small-scale

0.479

High

822151

TET5C
Terminal nucleotidyltransferase 5C

1

1

High-throughput

0.479

High

822154

DDX46
Probable ATP-dependent RNA helicase DDX46

1

1

High-throughput

0.479

High

109375

G5E9A7
DM1 locus, WD repeat containing

1

4

High-throughput

0.470

High

705261

GRN
Progranulin

1

1

High-throughput

0.470

High

822167

ZF64B
Zinc finger protein 64

1

0

High-throughput

0.426

High

2873

A0A0C4DG89
Probable ATP-dependent RNA helicase DDX46

1

1

High-throughput

0.407

High

822150

TMM31
Transmembrane protein 31

1

6

High-throughput

0.407

High

283807

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

0

High-throughput

0.279

Low

359603

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

0

High-throughput

0.279

Low

572349

CX7A2
Cytochrome c oxidase subunit 7A2, mitochondrial

1

0

High-throughput

0.279

Low

577949

QCR7
Cytochrome b-c1 complex subunit 7

1

0

High-throughput

0.279

Low

717037

ECHM
Enoyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.279

Low

822147

SGCB
Beta-sarcoglycan

1

0

High-throughput

0.279

Low

822157

IPRI
Inositol 1,4,5-trisphosphate receptor-interacting protein

1

0

High-throughput

0.279

Low

822160

NOC3L
Nucleolar complex protein 3 homolog

1

0

High-throughput

0.279

Low

822162

LGAT1
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1

1

0

High-throughput

0.279

Low

822165

SFXN1
Sideroflexin-1

1

0

High-throughput

0.279

Low

822166

ZDBF2
DBF4-type zinc finger-containing protein 2

1

0

High-throughput

0.279

Low

822169

STML2
Stomatin-like protein 2, mitochondrial

1

0

High-throughput

0.279

Low

822172

HIG1A
HIG1 domain family member 1A, mitochondrial

1

0

High-throughput

0.279

Low

822174

COF2
Cofilin-2

1

0

High-throughput

0.279

Low

822176

TMED3
Transmembrane emp24 domain-containing protein 3

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025