HitPredict

Interactor 1: TITIN (Q8WZ42)
Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)
Gene: TTN

Interactor 2: TITIN (Q8WZ42)
Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)
Gene: TTN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.911

The method score is based on:

Property Details
Experiments 23414517, 16407954, 16962974, 9804419
Identification Methods two hybrid, bimolecular fluorescence complementation, fluorescent resonance energy transfer, nuclear magnetic resonance, x-ray crystallography, two hybrid fragment pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains fn3~fn3, I-set~fn3, Pkinase~fn3, I-set~I-set, I-set~Pkinase, Pkinase~Pkinase
Common GO terms GO:0000794 - condensed nuclear chromosome
GO:0002020 - protease binding
GO:0003300 - cardiac muscle hypertrophy
GO:0004674 - protein serine/threonine kinase activity
GO:0004713 - protein tyrosine kinase activity
and 38 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 34350
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024