HitPredict

Interactor 1: SHRPN (Q91WA6)
Sharpin (Shank-associated RH domain-interacting protein) (Shank-interacting protein-like 1) (mSIPL1)
Gene: Sharpin

Interactor 2: RNF31 (Q924T7)
E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (Putative Ariadne-like ubiquitin ligase) (PAUL) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31)
Gene: RNF31

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 0.60 0.703

The method score is based on:

Property Details
Experiments 29694895, 21455181, 24461064, 21455180
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation, molecular sieving
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0004842 - ubiquitin-protein transferase activity
GO:0005829 - cytosol
GO:0033209 - tumor necrosis factor-mediated signaling pathway
GO:0042742 - defense response to bacterium
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
and 3 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 380
Mm

1 1066
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024