HitPredict

Interactor 1: EED (Q921E6)
Polycomb protein EED
Gene: EED

Interactor 2: ARC1B (Q9WV32)
Actin-related protein 2/3 complex subunit 1B (Arp2/3 complex 41 kDa subunit) (p41-ARC)
Gene: Arpc1b

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 441 Mm			1 372
+	Mm
		921804 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		GBB2_MOUSE (128-366): 3.79e-38: 141: 13.53
+	Hs
		245633 TBL1X_HUMAN (13-441): 1.12e-73: 243: 11.39		TBL1R_HUMAN (1-173): 2.1e-46: 167: 13.19
+	Hs
		245630 TBL1X_HUMAN (13-441): 1.12e-73: 243: 11.39		TBL1Y_HUMAN (1-171): 1.61e-32: 129: 13.33
+	Hs
		168822 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		ARC1B_HUMAN (1-372): 1.53e-79: 249: 97.31
+	Sc
		630844 NLE1_YEAST (4-263): 1.23e-51: 183: 14.05		NLE1_YEAST (129-367): 3.04e-40: 150: 11.81
+	Hs
		1309163 TBL1R_HUMAN (4-335): 2.6e-56: 195: 11.40		TBL1Y_HUMAN (1-171): 1.61e-32: 129: 13.33
+	Hs
		1281292 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		FBXW7_HUMAN (80-366): 1.39e-57: 200: 12.76
+	Hs
		245546 TBL1X_HUMAN (13-441): 1.12e-73: 243: 11.39		TBL1X_HUMAN (7-83): 1.46e-13: 73.9: 20.78
+	Dm
		1358859 FBXW7_DROME (224-441): 2.22e-25: 111: 15.53		WDS_DROME (1-233): 4e-56: 189: 13.87
+	Dm
		1358845 WDS_DROME (267-440): 1.02e-23: 103: 15.34		WDS_DROME (1-233): 4e-56: 189: 13.87
+	Hs
		903418 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		WDR5_HUMAN (173-365): 3.46e-46: 162: 15.82
+	Hs
		1240442 POC1A_HUMAN (177-440): 1.72e-50: 177: 14.29		POC1B_HUMAN (1-82): 1.4e-20: 94.7: 10.98
+	Ca
		483033 TUP1_CANAL (4-179): 2.42e-26: 113: 10.38		TUP1_CANAL (141-362): 4.37e-39: 147: 12.93
+	Hs
		903428 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		WDR5_HUMAN (173-365): 3.46e-46: 162: 15.82
+	Hs
		903349 WDR5B_HUMAN (279-439): 2.9e-21: 96.1: 12.27		WDR5_HUMAN (173-365): 3.46e-46: 162: 15.82
+	Hs
		903551 NLE1_HUMAN (4-124): 2.95e-18: 88.8: 9.09		WDR5_HUMAN (173-365): 3.46e-46: 162: 15.82