HitPredict

Interactor 1: TCPW (Q92526)
T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (CCT-zeta-like) (Chaperonin containing T-complex polypeptide 1 subunit 6B) (TCP-1-zeta-like) (Testis-specific Tcp20) (Testis-specific protein TSA303)
Gene: CCT6B

Interactor 2: DTL (Q9NZJ0)
Denticleless protein homolog (DDB1- and CUL4-associated factor 2) (Lethal(2) denticleless protein homolog) (Retinoic acid-regulated nuclear matrix-associated protein)
Gene: DTL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 530 Hs			1 730
+	Hs
		1306712 TCPH_HUMAN (2-529): 0: 568: 27.43		DTL_HUMAN (1-730): 8.94e-163: 489: 100.00
+	Sp
		293558 TCPZ_SCHPO (7-530): 0: 610: 59.77		CDT2_SCHPO (52-391): 1.12e-72: 246: 24.66
+	Sp
		953439 TCPH_SCHPO (3-527): 0: 551: 25.70		CDT2_SCHPO (52-391): 1.12e-72: 246: 24.66
+	Hs
		1202777 TCPH_HUMAN (2-529): 0: 568: 27.43		WDR5B_HUMAN (190-502): 2.83e-55: 194: 16.51
+	Hs
		903467 TCPH_HUMAN (2-529): 0: 568: 27.43		WDR5_HUMAN (11-243): 2.2e-54: 192: 13.95
+	Hs
		770968 TCPZ_HUMAN (1-530): 0: 558: 85.85		FBXW7_HUMAN (175-521): 4.51e-54: 200: 12.16
+	Hs
		770916 TCPZ_HUMAN (1-530): 0: 558: 85.85		WDR5B_HUMAN (190-502): 2.83e-55: 194: 16.51
+	Hs
		770771 TCPZ_HUMAN (1-530): 0: 558: 85.85		WDR5_HUMAN (11-243): 2.2e-54: 192: 13.95
+	Hs
		826601 TCPG_HUMAN (3-527): 0: 551: 28.20		WDR5_HUMAN (11-243): 2.2e-54: 192: 13.95
+	Hs
		770974 TCPZ_HUMAN (1-530): 0: 558: 85.85		SNR40_HUMAN (258-581): 7.14e-39: 149: 13.90
+	Hs
		792942 TCPG_HUMAN (3-527): 0: 551: 28.20		LIS1_HUMAN (260-499): 2.94e-36: 143: 15.23
+	Hs
		1240450 TCPH_HUMAN (2-529): 0: 568: 27.43		POC1A_HUMAN (256-429): 6.94e-28: 118: 24.71
+	Sp
		293559 TCPZ_SCHPO (7-530): 0: 610: 59.77		YN55_SCHPO (142-393): 1.21e-12: 71.1: 9.93
+	Hs
		770932 TCPZ_HUMAN (1-530): 0: 558: 85.85		POC1A_HUMAN (256-429): 6.94e-28: 118: 24.71
+	Hs
		236248 TCPH_HUMAN (2-529): 0: 568: 27.43		PRP17_HUMAN (16-169): 9.6e-20: 95.8: 16.97
+	Hs
		1306704 TCPH_HUMAN (2-529): 0: 568: 27.43		NLE1_HUMAN (343-590): 4e-15: 80.5: 10.97
+	Hs
		1306645 TCPH_HUMAN (2-529): 0: 568: 27.43		TBL1Y_HUMAN (345-587): 1.16e-12: 73.2: 12.95
+	Hs
		771069 TCPZ_HUMAN (1-530): 0: 558: 85.85		NLE1_HUMAN (343-590): 4e-15: 80.5: 10.97
+	Hs
		771009 TCPZ_HUMAN (1-530): 0: 558: 85.85		TBL1Y_HUMAN (345-587): 1.16e-12: 73.2: 12.95
+	Sp
		953440 TCPH_SCHPO (3-527): 0: 551: 25.70		YN55_SCHPO (142-393): 1.21e-12: 71.1: 9.93