HitPredict

Interactor 1: P55G (Q92569)
Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK)
Gene: PIK3R3

Interactor 2: I20RA (Q9UHF4)
Interleukin-20 receptor subunit alpha (IL-20 receptor subunit alpha) (IL-20R-alpha) (IL-20RA) (Cytokine receptor class-II member 8) (Cytokine receptor family 2 member 8) (CRF2-8) (IL-20R1) (ZcytoR7)
Gene: IL20RA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 461 Hs			1 553
+	Hs
		655495 P85A_HUMAN (48-455): 9.1e-92: 295: 79.17		I20RA_HUMAN (1-553): 1.09e-179: 519: 100.00
+	Hs
		566001 P85A_HUMAN (48-455): 9.1e-92: 295: 79.17		INAR1_HUMAN (20-361): 6.82e-50: 182: 19.44
+	Hs
		665299 P55G_HUMAN (1-461): 6.94e-114: 344: 100.00		EPHA2_HUMAN (30-222): 8.71e-12: 70.1: 20.47
+	Hs
		655234 P85A_HUMAN (48-455): 9.1e-92: 295: 79.17		IL3RB_HUMAN (10-534): 1.51e-25: 113: 12.15
+	Hs
		522745 SRC_HUMAN (323-459): 8.26e-19: 90.8: 24.14		INGR1_HUMAN (12-452): 6.71e-88: 281: 16.52
+	Hs
		500948 P85A_HUMAN (48-455): 9.1e-92: 295: 79.17		GHR_HUMAN (20-455): 5.45e-12: 70.5: 11.47
+	Hs
		655219 P85A_HUMAN (48-455): 9.1e-92: 295: 79.17		EPHA2_HUMAN (30-222): 8.71e-12: 70.1: 20.47
+	Hs
		129180 P85B_HUMAN (56-453): 2.19e-87: 283: 74.12		GHR_HUMAN (20-455): 5.45e-12: 70.5: 11.47
+	Hs
		129208 P85B_HUMAN (56-453): 2.19e-87: 283: 74.12		EPHA2_HUMAN (30-222): 8.71e-12: 70.1: 20.47
+	Hs
		146590 SOCS2_HUMAN (40-144): 7.17e-30: 117: 28.95		PRLR_HUMAN (35-536): 3.47e-45: 170: 13.31
+	Hs
		560479 CISH_HUMAN (20-146): 8.4e-18: 84.8: 25.37		PRLR_HUMAN (35-536): 3.47e-45: 170: 13.31
+	Hs
		412051 FYN_HUMAN (326-459): 6.82e-20: 94.2: 26.06		IL3RB_HUMAN (10-534): 1.51e-25: 113: 12.15
+	Hs
		433612 LYN_HUMAN (298-458): 6.17e-18: 88.1: 24.85		IL3RB_HUMAN (10-534): 1.51e-25: 113: 12.15
+	Hs
		146586 SOCS2_HUMAN (40-144): 7.17e-30: 117: 28.95		GHR_HUMAN (20-455): 5.45e-12: 70.5: 11.47
+	Hs
		146597 SOCS2_HUMAN (40-144): 7.17e-30: 117: 28.95		EPHA2_HUMAN (30-222): 8.71e-12: 70.1: 20.47
+	Dm
		53796 ABL_DROME (323-459): 7.74e-23: 104: 25.90		A1Z921_DROME (32-542): 3.77e-11: 68.1: 12.92
+	Hs
		411611 LCK_HUMAN (309-458): 5.54e-21: 97.3: 25.95		EPHA2_HUMAN (30-222): 8.71e-12: 70.1: 20.47
+	Hs
		433601 LYN_HUMAN (298-458): 6.17e-18: 88.1: 24.85		EPHA2_HUMAN (30-222): 8.71e-12: 70.1: 20.47
+	Hs
		147489 SOCS6_HUMAN (47-165): 1.85e-17: 86.8: 31.06		EPHA2_HUMAN (30-222): 8.71e-12: 70.1: 20.47
+	Hs
		500974 CISH_HUMAN (20-146): 8.4e-18: 84.8: 25.37		GHR_HUMAN (20-455): 5.45e-12: 70.5: 11.47