Protein: HEY
Hairy/enhancer-of-split related with YRPW motif protein

Gene: HEY
Organism: Drosophila melanogaster
Interactions: 55
UniProt ID: Q7KM13

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0006355 - regulation of DNA-templated transcription
GO:0007219 - Notch signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

479026

ZEN1
Protein zerknuellt 1

1

13

High-throughput

0.698

High

1028564

ESMC
Enhancer of split mgamma protein

1

18

High-throughput

0.698

High

1175925

DPN
Protein deadpan

1

18

High-throughput

0.656

High

713683

ABDA
Homeobox protein abdominal-A

1

7

High-throughput

0.621

High

1014329

UBX
Homeotic protein ultrabithorax

1

10

High-throughput

0.621

High

852269

E78C
Ecdysone-induced protein 78C

1

20

High-throughput

0.541

High

1267449

FOXO
Forkhead box protein O

1

4

High-throughput

0.541

High

384903

HSP26
Heat shock protein 26

1

2

High-throughput

0.508

High

633099

CNC
Segmentation protein cap'n'collar

1

3

High-throughput

0.508

High

814659

PHP
Polyhomeotic-proximal chromatin protein

1

3

High-throughput

0.508

High

1267445

Q8T4E7
AT02038p

1

2

High-throughput

0.508

High

1267454

Q9VEB9
Sequence-specific single-stranded DNA-binding protein, isoform A

1

2

High-throughput

0.508

High

1171648

DTX
Protein deltex

1

0

High-throughput

0.486

High

1267461

Q9VRY7
GH13213p

1

0

High-throughput

0.486

High

85021

B7Z143
Protein interacting with Ttk69 and Sin3A, isoform D

1

1

High-throughput

0.481

High

94967

E1JGN7
Heterogeneous nuclear ribonucleoprotein K, isoform E

1

2

High-throughput

0.481

High

118033

M9MS50
non-specific serine/threonine protein kinase

1

4

High-throughput

0.481

High

1267442

Q8I0J6
Degringolade, isoform B

1

10

Small-scale

0.479

High

1171792

Q24044
Cell division cycle protein 20 homolog

1

4

High-throughput

0.464

High

1267443

Q8I0N3
RE31819p

1

2

High-throughput

0.464

High

1267448

Q95TJ6
LP01469p

1

1

High-throughput

0.464

High

1267453

Q9VBE2
RE40518p

1

2

High-throughput

0.464

High

1267467

Q9W219
GEO12575p1

1

1

High-throughput

0.464

High

1267139

Q7KHL0
Bancal protein

1

2

High-throughput

0.457

High

1267458

Q9VNV0
non-specific serine/threonine protein kinase

1

4

High-throughput

0.457

High

1267465

Q9VYL7
Protein interacting with Ttk69 and Sin3A, isoform C

1

1

High-throughput

0.457

High

1267440

Q7KQM8
Uncharacterized protein, isoform D

1

1

High-throughput

0.439

High

1267441

Q7KW26
MIP13633p

1

1

High-throughput

0.439

High

1267452

Q9VBE0
TweedleB

1

2

High-throughput

0.439

High

1267463

EMAL
Echinoderm microtubule-associated protein-like CG42247

1

6

High-throughput

0.439

High

1267446

Q8T8W4
AT21302p

1

1

High-throughput

0.417

High

1267451

Q9V493
GM15303p

1

1

High-throughput

0.417

High

1267471

Q9XZT0
EG:34F3.10 protein

1

1

High-throughput

0.417

High

1174329

RPR
Cell death protein rpr

1

0

High-throughput

0.282

High

56797

A1ZAJ8
FI17311p1

1

0

High-throughput

0.265

Low

68826

A8JR10
Bitesize, isoform E

1

0

High-throughput

0.265

Low

144576

PHM
Peptidylglycine alpha-hydroxylating monooxygenase

1

0

High-throughput

0.265

Low

719683

FUR2
Furin-like protease 2

1

0

High-throughput

0.265

Low

1262118

Q7JVH6
LD24696p

1

0

High-throughput

0.265

Low

1265468

Q7K2V7
Tetraspanin

1

0

High-throughput

0.265

Low

1266845

Q7K569
Glycerol-3-phosphate dehydrogenase

1

0

High-throughput

0.265

Low

1267450

SER7
Serine protease 7

1

0

High-throughput

0.265

Low

1267455

Q9VEY0
Uncharacterized protein, isoform C

1

0

High-throughput

0.265

Low

1267456

Q9VHH1
LD42037p

1

0

High-throughput

0.265

Low

1267457

VTU4
Vitelline membrane protein Vm32E

1

0

High-throughput

0.265

Low

1267459

Q9VPJ6
Uncharacterized protein, isoform A

1

0

High-throughput

0.265

Low

1267460

OTU1
Ubiquitin thioesterase Otu1

1

0

High-throughput

0.265

Low

1267462

VPS36
Vacuolar protein-sorting-associated protein 36

1

0

High-throughput

0.265

Low

1267464

Q9VV44
Cuticular protein 72Ea

1

0

High-throughput

0.265

Low

1267466

Q9W0H1
Uncharacterized protein, isoform A

1

0

High-throughput

0.265

Low

1267468

Q9W221
MIP04282p

1

0

High-throughput

0.265

Low

1267469

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.265

Low

1267470

Q9W5Y4
MIP18541p

1

0

High-throughput

0.265

Low

1267444

RT4I1
NAD(P)H oxidoreductase RTN4IP1, mitochondrial

1

0

High-throughput

0.251

Low

1267447

Q95R37
SD10969p

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025