HitPredict

Interactor 1: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Interactor 2: MAGI1 (Q96QZ7)
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (Atrophin-1-interacting protein 3) (AIP-3) (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Trinucleotide repeat-containing gene 19 protein) (WW domain-containing protein 3) (WWP3)
Gene: MAGI1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1164 Hs			1 1491
+	Hs
		149188 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		MAGI1_HUMAN (1-1491): 0: 756: 100.00
+	Mm
		1193537 TSC1_MOUSE (1-1164): 0: 695: 86.98		SCRIB_MOUSE (188-985): 3.11e-30: 132: 16.36
+	Hs
		1246414 TSC1_HUMAN (1-1164): 0: 725: 100.00		INADL_HUMAN (14-131): 7.48e-13: 76: 14.75
+	Mm
		1143516 TSC1_MOUSE (1-1164): 0: 695: 86.98		DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61
+	Hs
		1203612 Q86WV8_HUMAN (1-343): 3.4e-177: 526: 100.00		LNX1_HUMAN (13-376): 2.39e-12: 74.1: 11.92
+	Hs
		1051354 DCTN1_HUMAN (540-1022): 9.26e-59: 223: 16.33		KIBRA_HUMAN (301-430): 4.15e-15: 83.2: 34.04
+	Hs
		125451 DCTN1_HUMAN (540-1022): 9.26e-59: 223: 16.33		WWP2_HUMAN (215-434): 9.36e-15: 82: 29.39
+	Mm
		1143432 CACO1_MOUSE (665-1096): 3.09e-39: 158: 16.94		DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61
+	Mm
		936586 ROCK2_MOUSE (415-1021): 2.16e-25: 116: 11.09		DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61
+	Rn
		92840 CTRO_RAT (337-1025): 8.64e-25: 114: 9.83		DLG4_RAT (14-112): 2.35e-17: 90.2: 19.23
+	Mm
		823534 CTRO_MOUSE (337-1025): 1.01e-24: 114: 9.83		DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61
+	Hs
		149028 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		KIBRA_HUMAN (301-430): 4.15e-15: 83.2: 34.04
+	Hs
		149091 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		PARD3_HUMAN (362-806): 5.29e-13: 76.6: 16.74
+	Hs
		724926 MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40		LNX1_HUMAN (13-376): 2.39e-12: 74.1: 11.92
+	Hs
		149079 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		INADL_HUMAN (14-131): 7.48e-13: 76: 14.75
+	Hs
		148925 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		MAGI3_HUMAN (2-688): 2.39e-12: 74.4: 11.08
+	Hs
		149084 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		LNX1_HUMAN (13-376): 2.39e-12: 74.1: 11.92
+	Hs
		1220103 MYH4_HUMAN (393-969): 2.58e-19: 96.8: 11.22		KIBRA_HUMAN (301-430): 4.15e-15: 83.2: 34.04
+	Hs
		148800 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		SCRIB_HUMAN (838-1232): 4.22e-09: 63.5: 23.26
+	Dm
		1303380 MYSN_DROME (417-1038): 2.47e-19: 96.8: 9.88		PATJ_DROME (13-306): 9.56e-12: 71.9: 12.69