HitPredict

Interactor 1: LAR4B (Q92615)
La-related protein 4B (La ribonucleoprotein domain family member 4B) (La ribonucleoprotein domain family member 5) (La-related protein 5)
Gene: LARP4B

Interactor 2: G3BP2 (Q9UN86)
Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2)
Gene: G3BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	29395067, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	La~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol GO:0010494 - cytoplasmic stress granule
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 738 Hs			1 482
+	Hs
		1030391 LAR4B_HUMAN (1-738): 0: 654: 100.00		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		1174874 LARP4_HUMAN (50-738): 1.65e-168: 503: 36.78		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		1030314 LARP4_HUMAN (50-738): 1.65e-168: 503: 36.78		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		1268132 LAR4B_HUMAN (1-738): 0: 654: 100.00		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		1174830 LARP4_HUMAN (50-738): 1.65e-168: 503: 36.78		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		1162718 LARP1_HUMAN (31-367): 7.91e-52: 197: 16.19		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		1030304 LARP1_HUMAN (31-367): 7.91e-52: 197: 16.19		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		1030276 LARP7_HUMAN (154-461): 2.7e-44: 170: 15.43		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Dm
		1337345 LAR4_DROME (105-472): 1.16e-68: 248: 34.38		Q9VRD6_DROME (6-134): 3.16e-39: 140: 28.79
+	Sc
		634175 SRO9_YEAST (158-216): 8.85e-09: 60.3: 27.87		BRE5_YEAST (9-419): 2.98e-56: 197: 15.59