Protein: RNF41
E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1)

Gene: RNF41
Organism: Homo sapiens
Interactions: 153
UniProt ID: Q9H4P4

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005128 - erythropoietin receptor binding
GO:0005135 - interleukin-3 receptor binding
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

777079

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

5

20

Small-scale

0.930

High

1331797

RNF41
E3 ubiquitin-protein ligase NRDP1

5

18

Small-scale

0.923

High

1331804

BIRC6
Baculoviral IAP repeat-containing protein 6

4

20

Small-scale

0.899

High

228698

PRKN
E3 ubiquitin-protein ligase parkin

2

20

Small-scale

0.812

High

872214

RD23A
UV excision repair protein RAD23 homolog A

2

20

High-throughput

0.783

High

896376

UBE2K
Ubiquitin-conjugating enzyme E2 K

2

20

High-throughput

0.783

High

895912

UB2D3
Ubiquitin-conjugating enzyme E2 D3

2

20

Small-scale

0.778

High

1331807

ASB6
Ankyrin repeat and SOCS box protein 6

9

11

Small-scale

0.759

High

1230716

VPS52
Vacuolar protein sorting-associated protein 52 homolog

8

5

Small-scale

0.757

High

1305049

TTC1
Tetratricopeptide repeat protein 1

9

9

Small-scale

0.756

High

1331813

ENOPH
Enolase-phosphatase E1

6

1

Small-scale

0.733

High

1331799

CYBP
Calcyclin-binding protein

4

4

Small-scale

0.702

High

1138923

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

20

High-throughput

0.698

High

1283422

RN166
E3 ubiquitin-protein ligase RNF166

1

18

High-throughput

0.698

High

1331798

UBE2Z
Ubiquitin-conjugating enzyme E2 Z

1

20

High-throughput

0.698

High

1331806

HOME2
Homer protein homolog 2

4

8

Small-scale

0.696

High

1198958

ISCA2
Iron-sulfur cluster assembly 2 homolog, mitochondrial

5

0

Small-scale

0.692

High

601996

ERBB3
Receptor tyrosine-protein kinase erbB-3

7

16

Small-scale

0.678

High

1331808

AIRIM
AFG2-interacting ribosome maturation factor

3

1

High-throughput

0.675

High

1101291

CL16A
Protein CLEC16A

3

4

High-throughput

0.675

High

264098

TACC1
Transforming acidic coiled-coil-containing protein 1

3

3

Small-scale

0.671

High

216835

CREB3
Cyclic AMP-responsive element-binding protein 3

3

10

High-throughput

0.667

High

1031834

IFIT5
Interferon-induced protein with tetratricopeptide repeats 5

3

10

Small-scale

0.667

High

1331817

SGT1
Protein SGT1 homolog

3

10

Small-scale

0.667

High

1326578

SRR
Serine racemase

3

1

High-throughput

0.665

High

722039

RFC4
Replication factor C subunit 4

5

3

Small-scale

0.658

High

1310138

LZTS2
Leucine zipper putative tumor suppressor 2

2

20

Small-scale

0.631

High

533246

PLSL
Plastin-2

2

12

High-throughput

0.628

High

1062015

RHG19
Rho GTPase-activating protein 19

2

8

High-throughput

0.628

High

49047

SHOT1
Shootin-1

2

2

Small-scale

0.621

High

1146450

AR6P4
ADP-ribosylation factor-like protein 6-interacting protein 4

3

2

Small-scale

0.611

High

1295196

VCIP1
Deubiquitinating protein VCPIP1

2

1

Small-scale

0.611

High

301325

MTCL2
Microtubule cross-linking factor 2

3

15

Small-scale

0.609

High

1070922

RCN1
Reticulocalbin-1

3

3

High-throughput

0.609

High

165781

N4BP3
NEDD4-binding protein 3

3

17

High-throughput

0.607

High

1071011

ERBB4
Receptor tyrosine-protein kinase erbB-4

2

15

Small-scale

0.595

High

1168511

ZN517
Zinc finger protein 517

2

17

High-throughput

0.574

High

1186131

BHA15
Class A basic helix-loop-helix protein 15

2

2

High-throughput

0.574

High

1243687

NAV1
Neuron navigator 1

2

7

Small-scale

0.567

High

796483

ZAP70
Tyrosine-protein kinase ZAP-70

1

20

Small-scale

0.561

High

883388

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

1

15

Small-scale

0.561

High

1185532

KDM3B
Lysine-specific demethylase 3B

2

4

Small-scale

0.554

High

1232314

MTURN
Maturin

2

4

High-throughput

0.553

High

1237643

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

2

7

High-throughput

0.553

High

952625

H33
Histone H3.3

1

11

Small-scale

0.553

High

864104

AP2S1
AP-2 complex subunit sigma

1

6

Small-scale

0.552

High

1185597

RIR2B
Ribonucleoside-diphosphate reductase subunit M2 B

1

0

High-throughput

0.549

High

851286

MAT1
CDK-activating kinase assembly factor MAT1

1

7

High-throughput

0.541

High

1023341

TRI32
E3 ubiquitin-protein ligase TRIM32

1

18

High-throughput

0.541

High

1306583

TS101
Tumor susceptibility gene 101 protein

1

3

High-throughput

0.541

High

1318347

TRIM8
E3 ubiquitin-protein ligase TRIM8

1

20

High-throughput

0.541

High

234400

EVI5
Ecotropic viral integration site 5 protein homolog

1

4

High-throughput

0.536

High

672302

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

7

High-throughput

0.536

High

862311

NUBP1
Cytosolic Fe-S cluster assembly factor NUBP1

1

1

High-throughput

0.536

High

927527

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

928467

DYL1
Dynein light chain 1, cytoplasmic

1

4

High-throughput

0.536

High

1026651

FADD
FAS-associated death domain protein

1

13

High-throughput

0.536

High

1069271

2A5A
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform

1

2

High-throughput

0.536

High

1137462

RAIN
Ras-interacting protein 1

1

16

High-throughput

0.536

High

1160845

RFWD3
E3 ubiquitin-protein ligase RFWD3

1

20

High-throughput

0.536

High

1190191

CLAP1
CLIP-associating protein 1

1

5

High-throughput

0.536

High

1217630

NAV3
Neuron navigator 3

1

18

High-throughput

0.536

High

1233692

KLH36
Kelch-like protein 36

1

2

High-throughput

0.536

High

1271759

TANK
TRAF family member-associated NF-kappa-B activator

1

5

High-throughput

0.536

High

1291294

DYL2
Dynein light chain 2, cytoplasmic

1

4

High-throughput

0.536

High

1296785

MARK4
MAP/microtubule affinity-regulating kinase 4

1

6

High-throughput

0.536

High

1328745

REN3A
Regulator of nonsense transcripts 3A

1

1

High-throughput

0.536

High

1331810

ITSN2
Intersectin-2

1

8

High-throughput

0.536

High

1331812

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

1

20

High-throughput

0.536

High

1331820

SNCAP
Synphilin-1

1

13

High-throughput

0.536

High

1250823

VANG1
Vang-like protein 1

2

2

Small-scale

0.533

High

1331818

MTCL1
Microtubule cross-linking factor 1

2

9

Small-scale

0.533

High

72165

B3KSH4
Huntingtin interacting protein 2, isoform CRA_a

1

20

High-throughput

0.528

High

435761

IGF1R
Insulin-like growth factor 1 receptor

2

20

Small-scale

0.521

High

117450

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

0

High-throughput

0.513

High

533627

TNNT1
Troponin T, slow skeletal muscle

1

0

High-throughput

0.513

High

1183122

MARK2
Serine/threonine-protein kinase MARK2

1

9

Small-scale

0.512

High

1257133

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

1

15

Small-scale

0.512

High

429124

ADRB2
Beta-2 adrenergic receptor

1

4

Small-scale

0.504

High

395759

A4
Amyloid-beta precursor protein

1

9

High-throughput

0.501

High

815926

MTR1A
Melatonin receptor type 1A

1

4

High-throughput

0.494

High

825742

MTR1B
Melatonin receptor type 1B

1

4

High-throughput

0.494

High

485401

GLI4
Zinc finger protein GLI4

1

18

High-throughput

0.489

High

642795

ELAV4
ELAV-like protein 4

1

15

High-throughput

0.489

High

1075461

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

13

High-throughput

0.489

High

1103477

ZN284
Zinc finger protein 284

1

7

High-throughput

0.489

High

1217398

ZN584
Zinc finger protein 584

1

20

High-throughput

0.489

High

1234198

DCLK2
Serine/threonine-protein kinase DCLK2

1

15

High-throughput

0.489

High

1267923

LGAT1
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1

1

1

High-throughput

0.489

High

1290357

C1GLC
C1GALT1-specific chaperone 1

1

2

High-throughput

0.489

High

1313782

KIFC3
Kinesin-like protein KIFC3

1

10

High-throughput

0.489

High

151908

IRS4
Insulin receptor substrate 4

1

2

Small-scale

0.481

High

151193

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

9

Small-scale

0.479

High

200676

CP110
Centriolar coiled-coil protein of 110 kDa

1

1

Small-scale

0.479

High

266424

TAD2A
Transcriptional adapter 2-alpha

1

3

High-throughput

0.479

High

311832

TACC2
Transforming acidic coiled-coil-containing protein 2

1

7

Small-scale

0.479

High

374869

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

15

High-throughput

0.479

High

411494

INSR
Insulin receptor

1

20

Small-scale

0.479

High

487764

ANDR
Androgen receptor

1

16

Small-scale

0.479

High

598321

FLNA
Filamin-A

1

13

Small-scale

0.479

High

603241

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

3

Small-scale

0.479

High

615842

GCSP
Glycine dehydrogenase

1

3

High-throughput

0.479

High

802727

CRK
Adapter molecule crk

1

20

Small-scale

0.479

High

809172

UTRN
Utrophin

1

9

Small-scale

0.479

High

843903

FXR1
RNA-binding protein FXR1

1

13

Small-scale

0.479

High

844242

FXR2
RNA-binding protein FXR2

1

13

Small-scale

0.479

High

851356

NEK2
Serine/threonine-protein kinase Nek2

1

13

Small-scale

0.479

High

894806

RAB8A
Ras-related protein Rab-8A

1

6

Small-scale

0.479

High

989123

FMR1
Fragile X messenger ribonucleoprotein 1

1

13

Small-scale

0.479

High

999672

AHNK
Neuroblast differentiation-associated protein AHNAK

1

3

Small-scale

0.479

High

1042536

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1075750

SF01
Splicing factor 1

1

10

High-throughput

0.479

High

1170151

FA83H
Protein FAM83H

1

1

Small-scale

0.479

High

1198064

KAISO
Transcriptional regulator Kaiso

1

19

Small-scale

0.479

High

1201347

SERC5
Serine incorporator 5

1

5

Small-scale

0.479

High

1205726

HOME1
Homer protein homolog 1

1

15

Small-scale

0.479

High

1218188

CEP97
Centrosomal protein of 97 kDa

1

4

Small-scale

0.479

High

1224409

XRN1
5'-3' exoribonuclease 1

1

1

Small-scale

0.479

High

1309900

COR1B
Coronin-1B

1

12

Small-scale

0.479

High

1331802

RTN4
Reticulon-4

1

4

Small-scale

0.479

High

1331803

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

8

High-throughput

0.479

High

1331805

DBLOH
Diablo IAP-binding mitochondrial protein

1

2

Small-scale

0.479

High

1331811

CTNL1
Alpha-catulin

1

2

Small-scale

0.479

High

230275

SI1L3
Signal-induced proliferation-associated 1-like protein 3

1

2

Small-scale

0.470

High

2735

A0A0C4DG62
ADP-ribosylation factor-like protein 6-interacting protein 4

1

2

High-throughput

0.470

High

1151238

Q6FHY5
MEOX2 protein

1

20

High-throughput

0.470

High

158233

GIPC1
PDZ domain-containing protein GIPC1

1

0

Small-scale

0.458

High

1166680

CLC9A
C-type lectin domain family 9 member A

1

3

Small-scale

0.457

High

987292

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

17

High-throughput

0.457

High

1256616

CE192
Centrosomal protein of 192 kDa

1

2

High-throughput

0.445

High

817329

LEPR
Leptin receptor

1

7

Small-scale

0.439

High

838275

MEOX2
Homeobox protein MOX-2

1

20

High-throughput

0.439

High

1135441

WLS
Protein wntless homolog

1

0

Small-scale

0.438

High

1136782

IFFO2
Intermediate filament family orphan 2

1

20

Small-scale

0.437

High

1137568

RIF1
Telomere-associated protein RIF1

1

3

Small-scale

0.437

High

1330048

CPVL
Probable serine carboxypeptidase CPVL

1

2

Small-scale

0.437

High

1331280

PKHA4
Pleckstrin homology domain-containing family A member 4

1

15

High-throughput

0.437

High

1331800

Q9HCK3
KIAA1569 protein

1

2

High-throughput

0.437

High

1331809

DJB12
DnaJ homolog subfamily B member 12

1

4

Small-scale

0.437

High

1331814

MRTFB
Myocardin-related transcription factor B

1

4

Small-scale

0.437

High

1331815

VANG2
Vang-like protein 2

1

2

Small-scale

0.437

High

1331816

ZN281
Zinc finger protein 281

1

12

Small-scale

0.437

High

1331819

CD2AP
CD2-associated protein

1

17

Small-scale

0.437

High

110769

H7BXG1
C-type lectin domain containing 16A

1

4

High-throughput

0.407

High

1331801

IL23A
Interleukin-23 subunit alpha

3

0

High-throughput

0.347

High

454105

GIP
Gastric inhibitory polypeptide

2

0

High-throughput

0.328

High

532218

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.279

Low

1051756

NPAT
Protein NPAT

1

0

High-throughput

0.279

Low

1288797

RTP4
Receptor-transporting protein 4

1

0

High-throughput

0.279

Low

596595

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

0

Small-scale

0.249

Low

1261977

FACR1
Fatty acyl-CoA reductase 1

1

0

Small-scale

0.249

Low

110827

H7C0N4
Splicing factor 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024