Interactor 1: DYRK2 (Q92630)
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)
Gene: DYRK2

Interactor 2: DYRK4 (Q9NR20)
Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1)
Gene: DYRK4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.777

The method score is based on:

Property Details
Experiments 23602568
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer, tandem affinity purification, anti tag coimmunoprecipitation, bimolecular fluorescence complementation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0004712 - protein serine/threonine/tyrosine kinase activity
GO:0004713 - protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 3 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 601
Hs

1 520
+ Hs
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+ Dm
+ At
+ Dm
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+ Mm
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Last updated: 15 Jul 2024