HitPredict

Interactor 1: RND1 (Q92730)
Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1)
Gene: RND1

Interactor 2: OSBL8 (Q9BZF1)
Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8)
Gene: OSBPL8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 232 Hs			1 889
+	Hs
		901234 RND3_HUMAN (1-232): 1.75e-100: 293: 58.20		OSBL8_HUMAN (1-889): 0: 1210: 100.00
+	Hs
		894394 CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43		OSBL8_HUMAN (1-889): 0: 1210: 100.00
+	Hs
		852607 RND2_HUMAN (12-232): 9.62e-80: 240: 53.15		OSBL8_HUMAN (1-889): 0: 1210: 100.00
+	Hs
		925589 RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42		OSBL8_HUMAN (1-889): 0: 1210: 100.00
+	Hs
		892574 RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89		OSBL8_HUMAN (1-889): 0: 1210: 100.00
+	Hs
		914333 RB11A_HUMAN (1-231): 1.91e-76: 231: 18.88		OSBL8_HUMAN (1-889): 0: 1210: 100.00
+	Hs
		951303 RHOG_HUMAN (11-198): 1.56e-76: 230: 37.77		OSBL8_HUMAN (1-889): 0: 1210: 100.00
+	Hs
		914300 RB11A_HUMAN (1-231): 1.91e-76: 231: 18.88		OSBL9_HUMAN (209-743): 5.35e-159: 484: 30.32
+	Hs
		925615 RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42		OSBL3_HUMAN (250-757): 1.65e-143: 449: 18.81
+	Hs
		892595 RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89		OSBL3_HUMAN (250-757): 1.65e-143: 449: 18.81
+	Hs
		951338 RHOG_HUMAN (11-198): 1.56e-76: 230: 37.77		OSBL3_HUMAN (250-757): 1.65e-143: 449: 18.81
+	Hs
		894383 CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43		OSB10_HUMAN (283-749): 1.96e-139: 435: 29.46
+	Hs
		925582 RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42		OSB10_HUMAN (283-749): 1.96e-139: 435: 29.46
+	Hs
		914326 RB11A_HUMAN (1-231): 1.91e-76: 231: 18.88		OSB10_HUMAN (283-749): 1.96e-139: 435: 29.46
+	Hs
		900859 RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94		OSB10_HUMAN (283-749): 1.96e-139: 435: 29.46
+	Hs
		951289 RHOG_HUMAN (11-198): 1.56e-76: 230: 37.77		OSB10_HUMAN (283-749): 1.96e-139: 435: 29.46
+	Hs
		925581 RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42		OSB11_HUMAN (345-749): 6.21e-130: 409: 29.62
+	Hs
		914325 RB11A_HUMAN (1-231): 1.91e-76: 231: 18.88		OSB11_HUMAN (345-749): 6.21e-130: 409: 29.62
+	Hs
		900858 RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94		OSB11_HUMAN (345-749): 6.21e-130: 409: 29.62
+	Hs
		951288 RHOG_HUMAN (11-198): 1.56e-76: 230: 37.77		OSB11_HUMAN (345-749): 6.21e-130: 409: 29.62