Protein: ZN622
Cytoplasmic 60S subunit biogenesis factor ZNF622 (Zinc finger protein 622) (Zinc finger-like protein 9)

Gene: ZN622, ZNF622
Organism: Homo sapiens
Interactions: 120
UniProt ID: Q969S3

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1381053

ZN622
Cytoplasmic 60S subunit biogenesis factor ZNF622

1

2

Small-scale

0.713

High

1381073

HECD1
E3 ubiquitin-protein ligase HECTD1

4

2

Small-scale

0.617

High

1381062

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

1

Small-scale

0.603

High

447287

NPM
Nucleophosmin

2

0

High-throughput

0.602

High

1239903

CAVN1
Caveolae-associated protein 1

2

0

High-throughput

0.602

High

1314035

YAF2
YY1-associated factor 2

2

0

High-throughput

0.602

High

1359871

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

2

0

High-throughput

0.602

High

1381081

OAS3
2'-5'-oligoadenylate synthase 3

2

0

High-throughput

0.602

High

941228

IF6
Eukaryotic translation initiation factor 6

2

2

High-throughput

0.584

High

277769

H2AY
Core histone macro-H2A.1

2

0

High-throughput

0.580

High

422798

A4
Amyloid-beta precursor protein

2

0

High-throughput

0.577

High

242510

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

346159

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

0

High-throughput

0.559

High

1123748

DCTN1
Dynactin subunit 1

2

0

High-throughput

0.559

High

519542

MYBB
Myb-related protein B

1

0

Small-scale

0.549

High

396665

ESR1
Estrogen receptor

2

0

High-throughput

0.547

High

582911

EZRI
Ezrin

1

1

High-throughput

0.536

High

767484

RADI
Radixin

1

1

High-throughput

0.536

High

992901

RACK1
Small ribosomal subunit protein RACK1

1

2

High-throughput

0.536

High

1027647

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

1

High-throughput

0.536

High

1381067

UN45A
Protein unc-45 homolog A

1

1

High-throughput

0.536

High

303608

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.513

High

391391

FRIL
Ferritin light chain

1

0

High-throughput

0.513

High

410987

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

0

High-throughput

0.513

High

693890

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.513

High

777310

AHR
Aryl hydrocarbon receptor

1

0

High-throughput

0.513

High

788733

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.513

High

834348

GARS
Glycine--tRNA ligase

1

0

High-throughput

0.513

High

859385

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.513

High

884186

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.513

High

970020

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

985802

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.513

High

997455

TBB4B
Tubulin beta-4B chain

1

0

High-throughput

0.513

High

1310288

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1360439

PSPC1
Paraspeckle component 1

1

0

High-throughput

0.513

High

1381064

RBM42
RNA-binding protein 42

1

0

High-throughput

0.513

High

1381069

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.513

High

1381071

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.513

High

1381076

TMED5
Transmembrane emp24 domain-containing protein 5

1

0

High-throughput

0.513

High

687279

HMGB2
High mobility group protein B2

1

0

High-throughput

0.486

High

185909

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

955451

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.480

High

325967

UBR5
E3 ubiquitin-protein ligase UBR5

1

1

High-throughput

0.479

High

342998

HERC2
E3 ubiquitin-protein ligase HERC2

1

1

High-throughput

0.479

High

606982

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

1058572

CKAP4
Cytoskeleton-associated protein 4

1

1

High-throughput

0.479

High

1088494

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

1

High-throughput

0.479

High

1132881

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

1

High-throughput

0.479

High

1204276

DJC21
DnaJ homolog subfamily C member 21

1

3

High-throughput

0.479

High

1220713

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.479

High

1227206

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

1356008

NOC3L
Nucleolar complex protein 3 homolog

1

1

High-throughput

0.479

High

1368555

KAT6A
Histone acetyltransferase KAT6A

1

2

High-throughput

0.479

High

1381056

NMD3
60S ribosomal export protein NMD3

1

2

High-throughput

0.479

High

1381060

DNJC2
DnaJ homolog subfamily C member 2

1

3

High-throughput

0.479

High

1381066

LSG1
Large subunit GTPase 1 homolog

1

2

High-throughput

0.479

High

1381074

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.479

High

1129967

MELK
Maternal embryonic leucine zipper kinase

1

0

Small-scale

0.460

High

48726

ESYT2
Extended synaptotagmin-2

1

0

High-throughput

0.458

High

132212

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.458

High

319957

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

370749

FOS
Protein c-Fos

1

0

High-throughput

0.458

High

554241

BMP4
Bone morphogenetic protein 4

1

0

High-throughput

0.458

High

589340

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

611273

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.458

High

696136

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

768826

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

787062

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

0

High-throughput

0.458

High

951327

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.458

High

965143

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.458

High

992050

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.458

High

1087679

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

0

High-throughput

0.458

High

1100197

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

1112117

KRR1
KRR1 small subunit processome component homolog

1

0

High-throughput

0.458

High

1138480

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1146759

PCBP1
Poly(rC)-binding protein 1

1

0

High-throughput

0.458

High

1235491

IFIX
Pyrin and HIN domain-containing protein 1

1

0

High-throughput

0.458

High

1254943

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1256544

CE128
Centrosomal protein of 128 kDa

1

0

High-throughput

0.458

High

1257096

PAXI1
PAX-interacting protein 1

1

0

High-throughput

0.458

High

1276598

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1280895

CNTRL
Centriolin

1

0

High-throughput

0.458

High

1289515

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1291335

LCA5
Lebercilin

1

0

High-throughput

0.458

High

1312571

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.458

High

1314191

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

0

High-throughput

0.458

High

1330894

CGAS
Cyclic GMP-AMP synthase

1

0

High-throughput

0.458

High

1351431

BRX1
Ribosome biogenesis protein BRX1 homolog

1

0

High-throughput

0.458

High

1357507

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.458

High

1360795

ASB11
Ankyrin repeat and SOCS box protein 11

1

0

High-throughput

0.458

High

1381054

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

1381057

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1381061

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

High-throughput

0.458

High

1381063

EBP2
Probable rRNA-processing protein EBP2

1

0

High-throughput

0.458

High

1381065

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.458

High

1381070

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1381077

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

1381078

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.458

High

1381080

RBM8A
RNA-binding protein 8A

1

0

High-throughput

0.458

High

1381058

DNJC1
DnaJ homolog subfamily C member 1

1

3

High-throughput

0.437

High

1381059

RHOV
Rho-related GTP-binding protein RhoV

1

1

High-throughput

0.437

High

1381072

XPO7
Exportin-7

1

3

High-throughput

0.437

High

537656

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.426

High

1056894

FMR1
Fragile X messenger ribonucleoprotein 1

1

0

High-throughput

0.426

High

1209483

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1381055

CC124
Coiled-coil domain-containing protein 124

1

0

Small-scale

0.426

High

1330670

BEND7
BEN domain-containing protein 7

2

0

High-throughput

0.316

High

665653

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

0

High-throughput

0.279

Low

1142129

P2RY6
P2Y purinoceptor 6

1

0

High-throughput

0.279

Low

1228691

C102B
Coiled-coil domain-containing protein 102B

1

0

High-throughput

0.279

Low

1328579

FA24B
Protein FAM24B

1

0

High-throughput

0.279

Low

1381075

SRPK3
SRSF protein kinase 3

1

0

High-throughput

0.279

Low

1381079

PCDA9
Protocadherin alpha-9

1

0

High-throughput

0.279

Low

720296

UFO
Tyrosine-protein kinase receptor UFO

1

0

High-throughput

0.249

Low

837773

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.249

Low

1111641

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.249

Low

1327116

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

1381068

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

58893

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025