HitPredict

Interactor 1: RND1 (Q92730)
Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1)
Gene: RND1

Interactor 2: RHG35 (Q9NRY4)
Rho GTPase-activating protein 35 (Glucocorticoid receptor DNA-binding factor 1) (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A)
Gene: ARHGAP35

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 22807448, 25531777
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ras~Ras, Ras~RhoGAP
Common GO terms GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0015629 - actin cytoskeleton
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 232
Hs

1 1499
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Last updated: 15 Jul 2024