Protein: Q8STG9
DSec61alpha (LD29847p) (Sec61 alpha subunit, isoform A) (Sec61 alpha subunit, isoform B)

Gene: Q8STG9, Sec61alpha
Organism: Drosophila melanogaster
Interactions: 146
UniProt ID: Q8STG9

Gene Ontology (top 5):
GO:0005048 - signal sequence binding
GO:0005783 - endoplasmic reticulum
GO:0005784 - Sec61 translocon complex
GO:0005791 - rough endoplasmic reticulum
GO:0006616 - SRP-dependent cotranslational protein targeting to membrane, translocation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1343116

Q8SY53
GH11935p

2

2

High-throughput

0.737

High

1343173

Q9VS57
RE14391p

1

6

High-throughput

0.575

High

197947

SURF4
Surfeit locus protein 4 homolog

2

2

High-throughput

0.571

High

652055

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

2

2

High-throughput

0.571

High

1173548

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

2

2

High-throughput

0.571

High

1343140

Q9VAL7
Calnexin 99A, isoform A

2

1

High-throughput

0.571

High

1343196

Q9W3N1
RH59310p

2

3

High-throughput

0.571

High

304223

ERD2
ER lumen protein-retaining receptor

2

0

High-throughput

0.547

High

1264508

Q7K110
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

2

0

High-throughput

0.547

High

1267377

Q7KLX3
Translocon-associated protein subunit delta

2

0

High-throughput

0.547

High

1343137

KRH2
Krueppel homolog 2

2

0

High-throughput

0.547

High

1343191

Q9VZL3
very-long-chain enoyl-CoA reductase

2

0

High-throughput

0.547

High

564996

ATNA
Sodium/potassium-transporting ATPase subunit alpha

2

2

High-throughput

0.521

High

782733

2AAA
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit

2

1

High-throughput

0.521

High

1266010

Q7K3M9
Solute carrier family 35 member F5

2

1

High-throughput

0.521

High

1343119

Q8T8W3
AT21416p

2

1

High-throughput

0.521

High

1343125

Q961E7
phosphorylase kinase

2

1

High-throughput

0.521

High

1343143

Q9VBU5
3-dehydrosphinganine reductase

2

1

High-throughput

0.521

High

1343179

Q9VV75
AT02348p

2

2

High-throughput

0.521

High

1343184

Q9VWL0
Mec2

2

1

High-throughput

0.521

High

1343197

Q9W414
Regulatory particle triple-A ATPase 4

2

4

High-throughput

0.504

High

1343136

PDIA6
Protein disulfide-isomerase A6 homolog

1

2

High-throughput

0.484

High

52675

A1Z729
NADP-retinol dehydrogenase

1

3

High-throughput

0.479

High

94128

D5AEK7
1-Acylglycerol-3-phosphate O-acyltransferase 3, isoform E

1

2

High-throughput

0.479

High

1260746

Q76NQ0
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.479

High

1343131

RAB5
Ras-related protein Rab5

1

1

High-throughput

0.479

High

1343141

Q9VAY2
Heat shock protein 83

1

1

High-throughput

0.479

High

1343144

Q9VBU6
Protein RER1

1

0

High-throughput

0.458

High

1343145

ATLAS
Atlastin

1

0

Small-scale

0.458

High

1343124

Q960C7
NADP-retinol dehydrogenase

1

3

High-throughput

0.445

High

1343160

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

1

High-throughput

0.445

High

1343170

Q9VRE0
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

1

2

High-throughput

0.445

High

1343178

Q9VV51
1-Acylglycerol-3-phosphate O-acyltransferase 3, isoform A

1

2

High-throughput

0.445

High

1343186

Q9VXG0
Cell division cycle 50, isoform A

1

1

High-throughput

0.445

High

1343195

Q9W1B5
Glycerol-3-phosphate acyltransferase 4, isoform C

1

2

High-throughput

0.445

High

1343198

Q9W4N8
LD30122p

1

1

High-throughput

0.445

High

1343199

Q9XZ53
dolichyl-diphosphooligosaccharide--protein glycotransferase

1

2

High-throughput

0.445

High

1343169

HERC2
Probable E3 ubiquitin-protein ligase HERC2

1

1

High-throughput

0.442

High

1011976

CCD1P
Probable cytochrome P450 12d1 proximal, mitochondrial

1

1

High-throughput

0.437

High

1265902

Q7K3K5
LD22804p

1

1

High-throughput

0.437

High

1269234

Q7KTD0
ABC-type glutathione-S-conjugate transporter

1

1

High-throughput

0.437

High

1305913

Q8IR34
Scamp, isoform D

1

1

High-throughput

0.437

High

1343200

Q9Y162
vesicle-fusing ATPase

1

2

High-throughput

0.437

High

1343117

Q8T3L1
long-chain-fatty-acid--CoA ligase

1

0

High-throughput

0.426

High

1343157

Q9VKU1
long-chain-fatty-acid--CoA ligase

1

0

High-throughput

0.426

High

1343163

SELT
Thioredoxin reductase-like selenoprotein T homolog CG3887

1

0

High-throughput

0.426

High

1343168

Q9VQX6
LP05054p

1

0

High-throughput

0.426

High

1343181

MBOA5
Lysophospholipid acyltransferase 5

1

0

High-throughput

0.426

High

1343193

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.426

High

1273630

VPS41
Vacuolar protein sorting-associated protein 41 homolog

1

5

High-throughput

0.417

High

1343120

Q8WTI8
PFTAIRE-interacting factor 1A

1

1

High-throughput

0.417

High

120925

M9PEG6
Zinc transporter 63C, isoform F

1

1

High-throughput

0.407

High

304130

RAB7
Ras-related protein Rab7

1

2

High-throughput

0.407

High

355945

O96692
small monomeric GTPase

1

3

High-throughput

0.407

High

874100

RALA
Ras-related protein Ral-a

1

2

High-throughput

0.407

High

1057334

ARL2
ADP-ribosylation factor-like protein 2

1

2

High-throughput

0.407

High

1202328

Q59DP9
Calcium-transporting ATPase

1

2

High-throughput

0.407

High

1262528

Q7JWI7
Hermes, isoform A

1

3

High-throughput

0.407

High

1263387

Q7JYX2
NADP-retinol dehydrogenase

1

3

High-throughput

0.407

High

1264114

Q7K0E6
Aspartate--tRNA ligase, cytoplasmic

1

1

High-throughput

0.407

High

1267690

Q7KMQ0
26S proteasome regulatory subunit 7

1

4

High-throughput

0.407

High

1268701

CCD1D
Probable cytochrome P450 12d1 distal, mitochondrial

1

1

High-throughput

0.407

High

1303350

SPT2
Protein SPT2 homolog

1

1

High-throughput

0.407

High

1343118

Q8T4G5
AFG3 like matrix AAA peptidase subunit 2, isoform A

1

2

High-throughput

0.407

High

1343132

Q9V3V6
26S proteasome regulatory complex subunit p50

1

5

High-throughput

0.407

High

1343134

Q9V405
26S proteasome regulatory subunit 6B

1

3

High-throughput

0.407

High

1343135

Q9V434
Asparagine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.407

High

1343142

Q9VBQ5
LD38433p

1

1

High-throughput

0.407

High

1343148

Q9VFV9
DnaJ-like-2, isoform A

1

2

High-throughput

0.407

High

1343156

Q9VK56
ABC-type glutathione-S-conjugate transporter

1

1

High-throughput

0.407

High

1343162

XRN2
5'-3' exoribonuclease 2 homolog

1

1

High-throughput

0.407

High

1343175

Q9VTQ9
AT06668p

1

6

High-throughput

0.407

High

1343189

Q9VXV6
Secretory carrier-associated membrane protein

1

1

High-throughput

0.407

High

1343192

Q9W0E4
Aminopeptidase

1

1

High-throughput

0.407

High

939745

CDS
Phosphatidate cytidylyltransferase, photoreceptor-specific

2

0

High-throughput

0.298

High

1069166

Q0E8E8
Phosphate carrier protein, mitochondrial

2

0

High-throughput

0.298

High

1237003

Q6NP72
GEO09659p1

2

0

High-throughput

0.298

High

1265032

JAGN
Protein jagunal

2

0

High-throughput

0.298

High

1268149

Q7KN94
Electron transfer flavoprotein subunit alpha

2

0

High-throughput

0.298

High

1304899

Q8IPV3
Uncharacterized protein, isoform A

2

0

High-throughput

0.298

High

1343122

FAXC
Failed axon connections

2

0

High-throughput

0.298

High

1343128

XPO1
Exportin-1

2

0

High-throughput

0.298

High

1343138

Q9V455
Importin subunit alpha

2

0

High-throughput

0.298

High

1343149

Q9VGF5
LP09696p

2

0

High-throughput

0.298

High

1343150

IPO9
Importin-9

2

0

High-throughput

0.298

High

1343154

Q9VK06
Phospholipid-transporting ATPase

2

0

High-throughput

0.298

High

1343165

Q9VN44
FI07923p

2

0

High-throughput

0.298

High

1343174

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

2

0

High-throughput

0.298

High

1343183

IDH3A
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

2

0

High-throughput

0.298

High

1343151

Q9VHB5
Vacuolar protein sorting-associated protein 45

1

0

High-throughput

0.282

High

51982

A1Z6J6
Uncharacterized protein

1

0

High-throughput

0.265

Low

235046

NOI
Splicing factor 3A subunit 3

1

0

High-throughput

0.265

Low

1285978

PPK28
Pickpocket protein 28

1

0

High-throughput

0.265

Low

1343123

FOXO
Forkhead box protein O

1

0

High-throughput

0.265

Low

1343130

CNO10
CCR4-NOT transcription complex subunit 10

1

0

High-throughput

0.265

Low

1343146

Q9VDK2
GH15831p

1

0

High-throughput

0.265

Low

1343159

GCM2
Transcription factor glial cells missing 2

1

0

High-throughput

0.265

Low

1343190

Q9VZ80
GEO13449p1

1

0

High-throughput

0.265

Low

1343194

SCN60
Sodium channel protein 60E

1

0

High-throughput

0.265

Low

831920

PEP
Zinc finger protein on ecdysone puffs

1

0

High-throughput

0.253

Low

1343180

Q9VVK3
Ccn

1

0

High-throughput

0.251

Low

55077

A1Z921
Frazzled, isoform B

1

0

Small-scale

0.249

Low

68948

MBD56
Methyl-CpG-binding domain protein 5/6 homolog sba

1

0

High-throughput

0.249

Low

704365

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

0

High-throughput

0.249

Low

1070979

Q0KI98
Tryptophan--tRNA ligase, cytoplasmic

1

0

High-throughput

0.249

Low

1265789

Q7K3J0
T-complex protein 1 subunit theta

1

0

High-throughput

0.249

Low

1343161

KPBB
Probable phosphorylase b kinase regulatory subunit beta

1

0

High-throughput

0.249

Low

1343167

Q9VQS4
Spindly

1

0

High-throughput

0.249

Low

1343177

PYRG
CTP synthase

1

0

High-throughput

0.249

Low

1343187

SUN
Protein stunted

1

0

High-throughput

0.249

Low

2716

A0A0B4LFU9
Anastral spindle 2, isoform B

1

0

High-throughput

0.232

Low

2784

UEX
Unextended protein

1

0

High-throughput

0.232

Low

68677

A8JQT2
Trichohyalin

1

0

High-throughput

0.232

Low

84941

B7Z0U6
Bestrophin 1, isoform B

1

0

High-throughput

0.232

Low

264605

KPYK
Pyruvate kinase

1

0

High-throughput

0.232

Low

356147

O96880
General transcription factor IIE subunit 1

1

0

High-throughput

0.232

Low

360550

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.232

Low

612390

ACTN
Alpha-actinin, sarcomeric

1

0

High-throughput

0.232

Low

669704

PSMD3
Probable 26S proteasome non-ATPase regulatory subunit 3

1

0

High-throughput

0.232

Low

715117

CLH
Clathrin heavy chain

1

0

High-throughput

0.232

Low

829650

ARF4
ADP ribosylation factor 4

1

0

High-throughput

0.232

Low

852194

COPB
Coatomer subunit beta

1

0

High-throughput

0.232

Low

929348

DHE3
Glutamate dehydrogenase, mitochondrial

1

0

High-throughput

0.232

Low

1071025

Q0KIB3
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.232

Low

1193680

Q4AB24
Myosin 95E, isoform F

1

0

High-throughput

0.232

Low

1195994

Q4QQB9
LP21121p

1

0

High-throughput

0.232

Low

1264023

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.232

Low

1343121

LDH
L-lactate dehydrogenase

1

0

High-throughput

0.232

Low

1343126

Q961H2
GH23453p

1

0

High-throughput

0.232

Low

1343127

Q9I7L3
Uncharacterized protein

1

0

High-throughput

0.232

Low

1343129

Q9U599
AT01821p

1

0

High-throughput

0.232

Low

1343133

Q9V3Z4
GH11341p

1

0

High-throughput

0.232

Low

1343139

Q9V9Q4
LD43819p

1

0

High-throughput

0.232

Low

1343147

RS5B
Small ribosomal subunit protein uS7B

1

0

High-throughput

0.232

Low

1343152

UNC50
Protein unc-50 homolog

1

0

High-throughput

0.232

Low

1343153

ARL8
ADP-ribosylation factor-like protein 8

1

0

High-throughput

0.232

Low

1343155

Q9VK46
Protein YIPF

1

0

High-throughput

0.232

Low

1343158

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.232

Low

1343164

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

0

High-throughput

0.232

Low

1343166

Q9VPR1
GH02075p

1

0

High-throughput

0.232

Low

1343171

Q9VRN1
Transmembrane 9 superfamily member

1

0

High-throughput

0.232

Low

1343172

Q9VS47
Lysosomal dipeptide transporter MFSD1

1

0

High-throughput

0.232

Low

1343176

FRL
Formin-like protein

1

0

High-throughput

0.232

Low

1343182

Q9VW54
26S proteasome non-ATPase regulatory subunit 2

1

0

High-throughput

0.232

Low

1343185

NUP35
Nucleoporin Nup35

1

0

High-throughput

0.232

Low

1343188

Q9VXQ5
Chaperonin containing TCP1 subunit 6

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025