HitPredict

Interactor 1: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Interactor 2: SRPK1 (Q96SB4)
SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)
Gene: SRPK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 530 Hs			1 655
+	Hs
		370259 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		SRPK1_HUMAN (1-655): 5.68e-157: 468: 94.64
+	Hs
		942851 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		SRPK2_HUMAN (48-655): 9.43e-136: 415: 57.97
+	Hs
		369378 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		SRPK2_HUMAN (48-655): 9.43e-136: 415: 57.97
+	Hs
		914671 ERR3_HUMAN (60-499): 2.69e-106: 327: 30.29		SRPK1_HUMAN (1-655): 5.68e-157: 468: 94.64
+	Hs
		369662 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		KS6A1_HUMAN (1-359): 2.84e-81: 273: 14.32
+	Hs
		369218 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		KS6A3_HUMAN (1-353): 1.92e-78: 266: 13.83
+	Hs
		834090 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		CLK3_HUMAN (484-653): 1.02e-60: 216: 28.65
+	Hs
		647937 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MARK3_HUMAN (409-655): 3.06e-47: 179: 12.65
+	Hs
		1183083 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MARK2_HUMAN (409-654): 1.03e-46: 178: 12.70
+	Hs
		369006 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		CDK2_HUMAN (414-653): 1.01e-65: 219: 19.43
+	Hs
		370471 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		CLK4_HUMAN (436-654): 5.51e-63: 218: 23.89
+	Hs
		369195 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		CLK3_HUMAN (484-653): 1.02e-60: 216: 28.65
+	Hs
		587205 RXRA_HUMAN (13-502): 1.6e-119: 361: 25.71		KS6A6_HUMAN (1-349): 8.64e-77: 261: 15.01
+	Hs
		369024 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		MARK3_HUMAN (409-655): 3.06e-47: 179: 12.65
+	Hs
		369888 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		MARK2_HUMAN (409-654): 1.03e-46: 178: 12.70
+	Hs
		611521 NR4A1_HUMAN (7-501): 3.18e-101: 318: 25.30		KS6A6_HUMAN (1-349): 8.64e-77: 261: 15.01
+	Hs
		487459 ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59		KS6A1_HUMAN (1-359): 2.84e-81: 273: 14.32
+	Hs
		414440 PRGR_HUMAN (149-459): 2.26e-41: 161: 32.82		CDK2_HUMAN (414-653): 1.01e-65: 219: 19.43