HitPredict

Interactor 1: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Interactor 2: PRC2C (Q9Y520)
Protein PRRC2C (BAT2 domain-containing protein 1) (HBV X-transactivated gene 2 protein) (HBV XAg-transactivated protein 2) (HLA-B-associated transcript 2-like 2) (Proline-rich and coiled-coil-containing protein 2C)
Gene: PRRC2C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30737378
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 488 Hs			1 2896
+	Mm
		1111987 HDAC4_MOUSE (1-377): 6.12e-133: 412: 23.89		PRC2C_MOUSE (1-2896): 0: 713: 83.24
+	Hs
		1270546 HDAC2_HUMAN (1-488): 0: 707: 100.00		NCOR2_HUMAN (685-2896): 1.59e-24: 115: 7.48
+	Hs
		1038652 HDAC1_HUMAN (1-443): 0: 642: 90.07		MINT_HUMAN (22-1891): 2.31e-43: 178: 9.12
+	Hs
		1270531 HDAC2_HUMAN (1-488): 0: 707: 100.00		SRRM2_HUMAN (10-1337): 2.52e-18: 95.2: 8.28
+	Hs
		1270390 HDAC2_HUMAN (1-488): 0: 707: 100.00		CIC_HUMAN (57-1435): 3.5e-10: 68.5: 9.73
+	Hs
		1038852 HDAC1_HUMAN (1-443): 0: 642: 90.07		NCOR2_HUMAN (685-2896): 1.59e-24: 115: 7.48
+	Hs
		1038645 HDAC1_HUMAN (1-443): 0: 642: 90.07		CIC_HUMAN (57-1435): 3.5e-10: 68.5: 9.73
+	Hs
		177416 HDAC3_HUMAN (10-431): 0: 574: 58.26		NCOR2_HUMAN (685-2896): 1.59e-24: 115: 7.48
+	Mm
		1157690 HDAC4_MOUSE (1-377): 6.12e-133: 412: 23.89		PRC2A_MOUSE (2007-2896): 2.45e-09: 65.6: 8.30
+	Mm
		1157685 HDAC4_MOUSE (1-377): 6.12e-133: 412: 23.89		PRC2B_MOUSE (1566-2896): 4.65e-09: 64.4: 7.39
+	Hs
		1354160 HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04		SRRM2_HUMAN (10-1337): 2.52e-18: 95.2: 8.28
+	Hs
		1260208 HDAC7_HUMAN (29-280): 1.96e-23: 106: 26.37		NCOR2_HUMAN (685-2896): 1.59e-24: 115: 7.48