Protein: GPN3
GPN-loop GTPase 3 (ATP-binding domain 1 family member C)

Gene: GPN3
Organism: Homo sapiens
Interactions: 110
UniProt ID: Q9UHW5

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0032991 - protein-containing complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1336406

GPN1
GPN-loop GTPase 1

7

10

Small-scale

0.960

High

1221390

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

6

3

High-throughput

0.672

High

169985

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

4

8

High-throughput

0.638

High

402763

RPC4
DNA-directed RNA polymerase III subunit RPC4

4

1

High-throughput

0.638

High

583622

RPB3
DNA-directed RNA polymerase II subunit RPB3

4

8

High-throughput

0.638

High

897658

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

4

3

High-throughput

0.638

High

913979

RPB7
DNA-directed RNA polymerase II subunit RPB7

4

4

High-throughput

0.638

High

1346864

RPC5
DNA-directed RNA polymerase III subunit RPC5

4

1

High-throughput

0.638

High

1347027

RPC2
DNA-directed RNA polymerase III subunit RPC2

4

13

High-throughput

0.638

High

872726

EPHA4
Ephrin type-A receptor 4

4

1

High-throughput

0.635

High

1347309

PIHD1
PIH1 domain-containing protein 1

4

1

High-throughput

0.633

High

1150720

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

4

2

High-throughput

0.617

High

583837

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

3

3

High-throughput

0.616

High

677049

RPB2
DNA-directed RNA polymerase II subunit RPB2

3

13

High-throughput

0.616

High

156080

RPC1
DNA-directed RNA polymerase III subunit RPC1

3

9

High-throughput

0.609

High

179875

RPA34
DNA-directed RNA polymerase I subunit RPA34

3

1

High-throughput

0.609

High

181481

RPB4
DNA-directed RNA polymerase II subunit RPB4

3

1

High-throughput

0.609

High

246399

SCN2B
Sodium channel subunit beta-2

3

1

High-throughput

0.609

High

317182

RPA1
DNA-directed RNA polymerase I subunit RPA1

3

9

High-throughput

0.609

High

625088

RPB1
DNA-directed RNA polymerase II subunit RPB1

3

9

High-throughput

0.609

High

738910

RPB9
DNA-directed RNA polymerase II subunit RPB9

3

5

High-throughput

0.609

High

854494

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

3

7

High-throughput

0.609

High

921190

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

3

4

High-throughput

0.609

High

1326453

RPA49
DNA-directed RNA polymerase I subunit RPA49

3

1

High-throughput

0.609

High

1334525

RPA2
DNA-directed RNA polymerase I subunit RPA2

3

13

High-throughput

0.609

High

1343466

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

3

6

High-throughput

0.609

High

1354017

CRNN
Cornulin

3

1

High-throughput

0.609

High

1355606

RPC10
DNA-directed RNA polymerase III subunit RPC10

3

5

High-throughput

0.609

High

1355609

RPC8
DNA-directed RNA polymerase III subunit RPC8

3

4

High-throughput

0.609

High

1314936

GTPB2
GTP-binding protein 2

2

1

High-throughput

0.606

High

125780

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

3

3

Small-scale

0.599

High

310857

VAPB
Vesicle-associated membrane protein-associated protein B/C

2

1

High-throughput

0.574

High

638420

RBTN2
Rhombotin-2

2

1

High-throughput

0.574

High

1354073

UXT
Protein UXT

2

1

High-throughput

0.574

High

484496

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

3

7

High-throughput

0.558

High

295691

RMP
Unconventional prefoldin RPB5 interactor 1

2

1

Small-scale

0.558

High

1299015

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

2

6

High-throughput

0.558

High

473933

GRL1A
DNA-directed RNA polymerase II subunit GRINL1A

2

2

High-throughput

0.504

High

177613

SIGL5
Sialic acid-binding Ig-like lectin 5

1

1

High-throughput

0.489

High

199970

SPIT2
Kunitz-type protease inhibitor 2

1

1

High-throughput

0.489

High

225434

MED14
Mediator of RNA polymerase II transcription subunit 14

1

2

High-throughput

0.489

High

600698

EPHA1
Ephrin type-A receptor 1

1

1

High-throughput

0.489

High

854394

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

3

High-throughput

0.489

High

865013

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

5

High-throughput

0.489

High

1162016

SPSB3
SPRY domain-containing SOCS box protein 3

1

2

High-throughput

0.489

High

1237332

SIGL1
SIGLEC family-like protein 1

1

1

High-throughput

0.489

High

1267403

F168A
Protein FAM168A

1

1

High-throughput

0.489

High

1274075

CUL5
Cullin-5

1

3

High-throughput

0.489

High

1297488

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.489

High

1302882

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.489

High

1318477

CD244
Natural killer cell receptor 2B4

1

1

High-throughput

0.489

High

1327933

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

3

High-throughput

0.489

High

1332516

RPAP3
RNA polymerase II-associated protein 3

1

1

High-throughput

0.489

High

1346445

MED17
Mediator of RNA polymerase II transcription subunit 17

1

1

High-throughput

0.489

High

1355595

PFD2
Prefoldin subunit 2

1

1

High-throughput

0.489

High

163428

XPO1
Exportin-1

1

12

High-throughput

0.479

High

749935

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.479

High

1251248

WDR48
WD repeat-containing protein 48

1

2

High-throughput

0.470

High

111487

J9JIF5
CXXC-type zinc finger protein 4

1

1

High-throughput

0.437

High

295365

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.437

High

476531

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.437

High

808997

YAP1
Transcriptional coactivator YAP1

1

5

Small-scale

0.437

High

1042780

CUL3
Cullin-3

1

3

High-throughput

0.437

High

1101361

CL16A
Protein CLEC16A

1

1

High-throughput

0.437

High

1137972

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

1

5

High-throughput

0.437

High

1332734

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.437

High

1354758

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

529869

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

473887

MYZAP
Myocardial zonula adherens protein

1

2

High-throughput

0.407

High

484423

RPC22
Protein POLR1D, isoform 2

1

1

High-throughput

0.407

High

1245685

MSPD2
Motile sperm domain-containing protein 2

1

1

High-throughput

0.407

High

1329419

CXXC4
CXXC-type zinc finger protein 4

1

1

High-throughput

0.407

High

906190

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

3

0

High-throughput

0.347

High

1355608

DAAM1
Disheveled-associated activator of morphogenesis 1

3

0

High-throughput

0.347

High

230440

ZC3H1
Zinc finger C3H1 domain-containing protein

2

0

High-throughput

0.328

High

591254

ACM3
Muscarinic acetylcholine receptor M3

2

0

High-throughput

0.328

High

1204532

VSIG1
V-set and immunoglobulin domain-containing protein 1

2

0

High-throughput

0.328

High

1308658

MICU1
Calcium uptake protein 1, mitochondrial

2

0

High-throughput

0.328

High

1347549

ASB6
Ankyrin repeat and SOCS box protein 6

2

0

High-throughput

0.328

High

1224807

ASPM
Abnormal spindle-like microcephaly-associated protein

2

0

High-throughput

0.318

High

1347150

MED9
Mediator of RNA polymerase II transcription subunit 9

2

0

High-throughput

0.313

High

48743

MED19
Mediator of RNA polymerase II transcription subunit 19

1

0

High-throughput

0.279

Low

204082

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.279

Low

206133

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.279

Low

260253

ENTP6
Ectonucleoside triphosphate diphosphohydrolase 6

1

0

High-throughput

0.279

Low

632439

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.279

Low

795584

AL3B1
Aldehyde dehydrogenase family 3 member B1

1

0

High-throughput

0.279

Low

863916

CRBB1
Beta-crystallin B1

1

0

High-throughput

0.279

Low

1109877

CMA1D
Protein CIMAP1D

1

0

High-throughput

0.279

Low

1158535

S27A4
Long-chain fatty acid transport protein 4

1

0

High-throughput

0.279

Low

1182975

SPT6H
Transcription elongation factor SPT6

1

0

High-throughput

0.279

Low

1186139

BHA15
Class A basic helix-loop-helix protein 15

1

0

High-throughput

0.279

Low

1202572

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.279

Low

1202755

P2RY8
P2Y purinoceptor 8

1

0

High-throughput

0.279

Low

1219097

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

1232249

EH1L1
EH domain-binding protein 1-like protein 1

1

0

High-throughput

0.279

Low

1253052

F174A
Membrane protein FAM174A

1

0

High-throughput

0.279

Low

1298317

DAA10
Dynein axonemal assembly factor 10

1

0

High-throughput

0.279

Low

1302139

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.279

Low

1303200

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.279

Low

1312772

MED18
Mediator of RNA polymerase II transcription subunit 18

1

0

High-throughput

0.279

Low

1345932

PDRG1
p53 and DNA damage-regulated protein 1

1

0

High-throughput

0.279

Low

1354101

P2RX2
P2X purinoceptor 2

1

0

High-throughput

0.279

Low

1355605

LAMP3
Lysosome-associated membrane glycoprotein 3

1

0

High-throughput

0.279

Low

1355607

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.279

Low

575613

EGR1
Early growth response protein 1

1

0

High-throughput

0.249

Low

824508

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

1327142

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low

313476

MED26
Mediator of RNA polymerase II transcription subunit 26

1

0

High-throughput

0.232

Low

1222628

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024