HitPredict

Interactor 1: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Interactor 2: MEP50 (Q9BQA1)
Methylosome protein WDR77 (Androgen receptor cofactor p44) (Methylosome protein 50) (MEP-50) (WD repeat-containing protein 77) (p44/Mep50)
Gene: WDR77

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	30282801
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 2442 Hs			1 342
+	Hs
		903405 CBP_HUMAN (1-2442): 0: 1104: 100.00		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		725424 EP300_HUMAN (1-2426): 0: 874: 55.06		COPB2_HUMAN (54-331): 3.17e-47: 172: 18.38
+	Hs
		903172 EP300_HUMAN (1-2426): 0: 874: 55.06		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		1262809 PHIP_HUMAN (1045-1205): 3.22e-45: 183: 30.36		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		631541 BRD2_HUMAN (1065-1195): 9.64e-34: 143: 30.53		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		1074799 PHIP_HUMAN (1045-1205): 3.22e-45: 183: 30.36		TAF5_HUMAN (178-328): 1.2e-21: 98: 18.42
+	Sp
		252179 YK82_SCHPO (698-1194): 1.8e-33: 142: 15.18		NLE1_SCHPO (204-340): 4.1e-33: 129: 16.55
+	Hs
		1074790 BRDT_HUMAN (1059-1195): 1.74e-34: 146: 25.55		TAF5_HUMAN (178-328): 1.2e-21: 98: 18.42
+	Hs
		1066968 BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89		TAF5_HUMAN (178-328): 1.2e-21: 98: 18.42
+	Hs
		631433 BRD2_HUMAN (1065-1195): 9.64e-34: 143: 30.53		TAF5_HUMAN (178-328): 1.2e-21: 98: 18.42
+	Sc
		744679 GCN5_YEAST (1110-1192): 5.75e-12: 72.4: 37.35		TAF5_YEAST (15-267): 2.96e-38: 146: 14.77
+	Hs
		196957 BRD2_HUMAN (1065-1195): 9.64e-34: 143: 30.53		PRP4_HUMAN (253-341): 3.86e-10: 62.8: 13.40
+	Sc
		863629 GCN5_YEAST (1110-1192): 5.75e-12: 72.4: 37.35		COPA_YEAST (131-323): 1.27e-23: 104: 16.81
+	Sc
		784417 GCN5_YEAST (1110-1192): 5.75e-12: 72.4: 37.35		COPB2_YEAST (15-314): 1.99e-22: 100: 14.47
+	Mm
		903669 KMT2C_MOUSE (1733-2440): 7.05e-13: 77.1: 11.27		WDR5_MOUSE (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		903374 KMT2C_HUMAN (1945-2437): 8.84e-10: 67.1: 13.89		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79