HitPredict

Interactor 1: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Interactor 2: TOPRS (Q9NS56)
E3 ubiquitin-protein ligase Topors (EC 2.3.2.27) (RING-type E3 ubiquitin transferase Topors) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3)
Gene: TOPORS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	28680062
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 2442 Hs			1 1045
+	Hs
		1067159 BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89		TOPRS_HUMAN (1-1045): 0: 731: 100.00
+	Hs
		1067006 BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89		NIPBL_HUMAN (362-1016): 7.16e-73: 267: 13.73
+	Hs
		1067060 BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89		THOC2_HUMAN (485-913): 3.17e-29: 128: 12.14