HitPredict

Interactor 1: EZH1 (Q92800)
Histone-lysine N-methyltransferase EZH1 (EC 2.1.1.356) (ENX-2) (Enhancer of zeste homolog 1)
Gene: EZH1

Interactor 2: DIDO1 (Q9BTC0)
Death-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1)
Gene: DIDO1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 747 Hs			1 2240
+	Hs
		1271104 EZH1_HUMAN (1-747): 0: 863: 100.00		NSRP1_HUMAN (2033-2240): 4.74e-23: 108: 18.27
+	Hs
		1080524 EZH2_HUMAN (8-746): 0: 719: 62.78		PRC2C_HUMAN (27-1904): 3.9e-50: 199: 9.83
+	Hs
		1080261 EZH2_HUMAN (8-746): 0: 719: 62.78		MINT_HUMAN (10-2011): 1.36e-47: 191: 9.73
+	Hs
		1017304 EZH2_HUMAN (8-746): 0: 719: 62.78		BPTF_HUMAN (82-420): 9.56e-40: 165: 14.29
+	Hs
		612982 EZH2_HUMAN (8-746): 0: 719: 62.78		TCEA1_HUMAN (573-816): 3.91e-44: 165: 18.15
+	Hs
		1080127 EZH2_HUMAN (8-746): 0: 719: 62.78		KMT2C_HUMAN (268-1949): 7.95e-19: 96.6: 10.24
+	Hs
		1017344 NSD3_HUMAN (556-728): 3.08e-53: 201: 32.78		BPTF_HUMAN (82-420): 9.56e-40: 165: 14.29
+	Hs
		1300928 SETD2_HUMAN (181-733): 3.89e-76: 271: 14.90		CIC_HUMAN (2-1657): 2.53e-13: 78.4: 7.87
+	Hs
		1296398 EHMT2_HUMAN (419-733): 7.51e-74: 262: 23.10		CIC_HUMAN (2-1657): 2.53e-13: 78.4: 7.87
+	Hs
		1300945 EHMT1_HUMAN (416-733): 2.04e-73: 261: 21.88		CIC_HUMAN (2-1657): 2.53e-13: 78.4: 7.87
+	Sp
		251615 SET1_SCHPO (609-731): 9.67e-23: 106: 43.20		SPP1_SCHPO (170-518): 1.08e-44: 170: 19.13
+	Dm
		1129089 SET1_DROME (612-733): 3.98e-19: 94.7: 39.52		CXXC1_DROME (240-586): 1.77e-45: 178: 14.75
+	Hs
		975335 KMT2A_HUMAN (620-734): 4.36e-19: 95.1: 42.24		CXXC1_HUMAN (245-393): 2.59e-34: 144: 26.75
+	Hs
		1349848 SET1B_HUMAN (620-733): 4.68e-19: 94.7: 41.38		CXXC1_HUMAN (245-393): 2.59e-34: 144: 26.75
+	Hs
		165726 SET1A_HUMAN (612-733): 1.12e-18: 93.6: 39.52		CXXC1_HUMAN (245-393): 2.59e-34: 144: 26.75
+	Hs
		165739 SET1A_HUMAN (612-733): 1.12e-18: 93.6: 39.52		PHF8_HUMAN (236-386): 7.12e-24: 112: 23.31
+	Hs
		975294 KMT2A_HUMAN (620-734): 4.36e-19: 95.1: 42.24		TITIN_HUMAN (19-1290): 3.32e-21: 104: 10.49
+	Hs
		975285 KMT2A_HUMAN (620-734): 4.36e-19: 95.1: 42.24		KMT2C_HUMAN (268-1949): 7.95e-19: 96.6: 10.24
+	Hs
		1243853 SET1B_HUMAN (620-733): 4.68e-19: 94.7: 41.38		KMT2C_HUMAN (268-1949): 7.95e-19: 96.6: 10.24
+	Hs
		165699 SET1A_HUMAN (612-733): 1.12e-18: 93.6: 39.52		KMT2C_HUMAN (268-1949): 7.95e-19: 96.6: 10.24