Protein: TM10C
tRNA methyltransferase 10 homolog C (HBV pre-S2 trans-regulated protein 2) (Mitochondrial ribonuclease P protein 1) (Mitochondrial RNase P protein 1) (RNA (guanine-9-)-methyltransferase domain-containing protein 1) (Renal carcinoma antigen NY-REN-49) (mRNA methyladenosine-N(1)-methyltransferase) (EC 2.1.1.-) (tRNA (adenine(9)-N(1))-methyltransferase) (EC 2.1.1.218) (tRNA (guanine(9)-N(1))-methyltransferase) (EC 2.1.1.221)

Gene: TM10C, TRMT10C
Organism: Homo sapiens
Interactions: 209
UniProt ID: Q7L0Y3

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0000964 - mitochondrial RNA 5'-end processing
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1271119

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

7

1

Small-scale

0.969

High

1271088

TM10C
tRNA methyltransferase 10 homolog C

1

1

Small-scale

0.647

High

1271121

RNZ2
Zinc phosphodiesterase ELAC protein 2

3

0

High-throughput

0.634

High

177562

MRPP3
Mitochondrial ribonuclease P catalytic subunit

1

1

Small-scale

0.618

High

1087432

GRSF1
G-rich sequence factor 1

3

0

Small-scale

0.613

High

207834

ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

3

1

High-throughput

0.609

High

1212572

HECD3
E3 ubiquitin-protein ligase HECTD3

3

1

High-throughput

0.609

High

139400

VMA5A
von Willebrand factor A domain-containing protein 5A

2

0

High-throughput

0.602

High

348584

AIFM1
Apoptosis-inducing factor 1, mitochondrial

2

1

High-throughput

0.584

High

882745

EFTU
Elongation factor Tu, mitochondrial

2

2

Small-scale

0.584

High

978109

RHOB
Rho-related GTP-binding protein RhoB

2

7

High-throughput

0.584

High

1271096

SERB1
SERPINE1 mRNA-binding protein 1

2

1

High-throughput

0.584

High

396398

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

541563

FGFR1
Fibroblast growth factor receptor 1

2

3

High-throughput

0.571

High

242094

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

279809

CISY
Citrate synthase, mitochondrial

2

0

High-throughput

0.559

High

1113505

CUL3
Cullin-3

2

0

High-throughput

0.559

High

1162390

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

0

High-throughput

0.559

High

1271155

ANLN
Anillin

2

0

High-throughput

0.559

High

537396

HSP7C
Heat shock cognate 71 kDa protein

2

0

High-throughput

0.547

High

1123328

ICT1
Large ribosomal subunit protein mL62

2

0

High-throughput

0.547

High

431169

LA
Lupus La protein

1

1

High-throughput

0.536

High

140978

NOP56
Nucleolar protein 56

1

0

High-throughput

0.513

High

484579

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

530007

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.513

High

1100856

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.513

High

1199425

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

1

0

High-throughput

0.513

High

1271116

TRNT1
CCA tRNA nucleotidyltransferase 1, mitochondrial

1

0

High-throughput

0.513

High

1271154

TF7L2
Transcription factor 7-like 2

1

0

High-throughput

0.513

High

1271161

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.513

High

185803

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

281989

MPPB
Mitochondrial-processing peptidase subunit beta

1

1

High-throughput

0.479

High

287316

RF1M
Peptide chain release factor 1, mitochondrial

1

2

High-throughput

0.479

High

315720

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

372396

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

406318

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

412146

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

466324

RHOC
Rho-related GTP-binding protein RhoC

1

6

High-throughput

0.479

High

786149

LONM
Lon protease homolog, mitochondrial

1

1

High-throughput

0.479

High

801388

HSPA9
Stress-70 protein, mitochondrial

1

1

High-throughput

0.479

High

856298

IF2M
Translation initiation factor IF-2, mitochondrial

1

1

High-throughput

0.479

High

962198

RHOA
Transforming protein RhoA

1

7

High-throughput

0.479

High

988475

RAC1
Ras-related C3 botulinum toxin substrate 1

1

6

High-throughput

0.479

High

996218

EF1A1
Elongation factor 1-alpha 1

1

1

Small-scale

0.479

High

1083651

MPPA
Mitochondrial-processing peptidase subunit alpha

1

1

High-throughput

0.479

High

1135897

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

3

High-throughput

0.479

High

1138340

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

1194173

LARP7
La-related protein 7

1

1

High-throughput

0.479

High

1207407

HABP4
Intracellular hyaluronan-binding protein 4

1

1

High-throughput

0.479

High

1240294

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

1

High-throughput

0.479

High

1271091

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

3

High-throughput

0.479

High

1271101

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1271104

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

2

High-throughput

0.479

High

1271105

FAKD4
FAST kinase domain-containing protein 4

1

3

High-throughput

0.479

High

1271106

MCUR1
Mitochondrial calcium uniporter regulator 1

1

1

High-throughput

0.479

High

1271108

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

1

High-throughput

0.479

High

1271109

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

1

High-throughput

0.479

High

1271118

EFGM
Elongation factor G, mitochondrial

1

2

High-throughput

0.479

High

1271130

RT26
Small ribosomal subunit protein mS26

1

1

High-throughput

0.479

High

1271135

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

1

High-throughput

0.479

High

1271136

CLPB
Mitochondrial disaggregase

1

1

Small-scale

0.479

High

1271139

MTRFR
Mitochondrial translation release factor in rescue

1

2

High-throughput

0.479

High

1271158

DDX28
Probable ATP-dependent RNA helicase DDX28

1

1

High-throughput

0.479

High

1271164

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

3

High-throughput

0.479

High

1271167

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

2

High-throughput

0.479

High

1271168

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1271169

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.479

High

1271174

DJC15
DnaJ homolog subfamily C member 15

1

1

High-throughput

0.479

High

61536

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.458

High

66223

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.458

High

125514

LEG9
Galectin-9

1

0

High-throughput

0.458

High

183671

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.458

High

193288

SOCS1
Suppressor of cytokine signaling 1

1

0

Small-scale

0.458

High

319865

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

324947

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

350054

SNAI1
Zinc finger protein SNAI1

1

0

High-throughput

0.458

High

350909

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

361643

OTC
Ornithine transcarbamylase, mitochondrial

1

0

High-throughput

0.458

High

363478

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

401039

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

414089

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

471104

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.458

High

472843

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

482502

F16P1
Fructose-1,6-bisphosphatase 1

1

0

High-throughput

0.458

High

505439

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

1

0

High-throughput

0.458

High

519146

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

532706

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

589001

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

606872

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

608644

DDX5
Probable ATP-dependent RNA helicase DDX5

1

0

Small-scale

0.458

High

695788

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

760951

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

0

Small-scale

0.458

High

828823

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

830962

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

841805

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

851932

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

879215

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

883469

DHE4
Glutamate dehydrogenase 2, mitochondrial

1

0

Small-scale

0.458

High

904868

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

908412

HDGF
Hepatoma-derived growth factor

1

0

High-throughput

0.458

High

957426

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

970695

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

976749

ERF1
Eukaryotic peptide chain release factor subunit 1

1

0

Small-scale

0.458

High

1024083

TFAM
Transcription factor A, mitochondrial

1

0

High-throughput

0.458

High

1026440

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

1033710

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

1035722

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.458

High

1036112

MMSA
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial

1

0

Small-scale

0.458

High

1048570

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1058100

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1090446

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

0

High-throughput

0.458

High

1106973

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1117764

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.458

High

1140471

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1142581

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

1207054

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1211772

SYRM
Probable arginine--tRNA ligase, mitochondrial

1

0

Small-scale

0.458

High

1234428

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

1260597

ASXL2
Putative Polycomb group protein ASXL2

1

0

High-throughput

0.458

High

1271089

DHX30
ATP-dependent RNA helicase DHX30

1

0

High-throughput

0.458

High

1271090

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

1271092

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1271093

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.458

High

1271094

CEP57
Centrosomal protein of 57 kDa

1

0

High-throughput

0.458

High

1271095

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.458

High

1271099

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

1271102

KAT6A
Histone acetyltransferase KAT6A

1

0

High-throughput

0.458

High

1271103

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.458

High

1271107

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

1271110

FMT
Methionyl-tRNA formyltransferase, mitochondrial

1

0

High-throughput

0.458

High

1271111

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

1271112

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.458

High

1271117

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.458

High

1271120

PKP2
Plakophilin-2

1

0

Small-scale

0.458

High

1271122

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.458

High

1271123

MTG1
Mitochondrial ribosome-associated GTPase 1

1

0

High-throughput

0.458

High

1271124

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.458

High

1271125

DUS26
Dual specificity protein phosphatase 26

1

0

High-throughput

0.458

High

1271126

TR61B
tRNA

1

0

High-throughput

0.458

High

1271127

KIFC1
Kinesin-like protein KIFC1

1

0

Small-scale

0.458

High

1271128

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.458

High

1271132

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

0

High-throughput

0.458

High

1271133

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

0

High-throughput

0.458

High

1271134

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1271137

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.458

High

1271138

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

1271141

MTG2
Mitochondrial ribosome-associated GTPase 2

1

0

High-throughput

0.458

High

1271143

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1271144

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1271145

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

1271146

NT5D2
5'-nucleotidase domain-containing protein 2

1

0

Small-scale

0.458

High

1271148

SYCM
Probable cysteine--tRNA ligase, mitochondrial

1

0

Small-scale

0.458

High

1271152

SYSM
Serine--tRNA ligase, mitochondrial

1

0

Small-scale

0.458

High

1271153

NGRN
Neugrin

1

0

High-throughput

0.458

High

1271159

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

1271160

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

0

High-throughput

0.458

High

1271162

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

1271165

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1271166

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

1271171

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.458

High

1271172

RTCB
RNA-splicing ligase RtcB homolog

1

0

Small-scale

0.458

High

1271175

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

High-throughput

0.458

High

1102490

IFIT5
Interferon-induced protein with tetratricopeptide repeats 5

1

1

High-throughput

0.445

High

1252451

LN28B
Protein lin-28 homolog B

1

1

High-throughput

0.445

High

1271147

LN28A
Protein lin-28 homolog A

1

1

High-throughput

0.445

High

126665

RHOD
Rho-related GTP-binding protein RhoD

1

9

High-throughput

0.437

High

581133

RAC2
Ras-related C3 botulinum toxin substrate 2

1

5

High-throughput

0.437

High

610011

VGFR1
Vascular endothelial growth factor receptor 1

1

2

High-throughput

0.437

High

650253

FGFR3
Fibroblast growth factor receptor 3

1

3

High-throughput

0.437

High

720262

UFO
Tyrosine-protein kinase receptor UFO

1

1

High-throughput

0.437

High

910107

RND2
Rho-related GTP-binding protein RhoN

1

8

High-throughput

0.437

High

955321

CDC42
Cell division control protein 42 homolog

1

7

High-throughput

0.437

High

1015547

RHOG
Rho-related GTP-binding protein RhoG

1

5

High-throughput

0.437

High

1151749

RHOH
Rho-related GTP-binding protein RhoH

1

7

High-throughput

0.437

High

1254370

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

1270870

RHOU
Rho-related GTP-binding protein RhoU

1

8

High-throughput

0.437

High

1271114

RHOV
Rho-related GTP-binding protein RhoV

1

7

High-throughput

0.437

High

1271131

RHBT2
Rho-related BTB domain-containing protein 2

1

5

High-throughput

0.437

High

1271140

RHOJ
Rho-related GTP-binding protein RhoJ

1

7

High-throughput

0.437

High

1271149

RHOF
Rho-related GTP-binding protein RhoF

1

8

High-throughput

0.437

High

985730

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.426

High

1209310

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1051780

EF1A2
Elongation factor 1-alpha 2

1

1

High-throughput

0.407

High

1271170

GAB2
GRB2-associated-binding protein 2

1

1

High-throughput

0.407

High

1271100

PTPRU
Receptor-type tyrosine-protein phosphatase U

2

0

High-throughput

0.298

High

157539

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

179942

BET1
BET1 homolog

1

0

High-throughput

0.249

Low

293914

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

693011

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.249

Low

929980

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

0

High-throughput

0.249

Low

939934

TPTE
Putative tyrosine-protein phosphatase TPTE

1

0

High-throughput

0.249

Low

1127919

PDIA5
Protein disulfide-isomerase A5

1

0

Small-scale

0.249

Low

1205438

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.249

Low

1211642

FBP1L
Formin-binding protein 1-like

1

0

High-throughput

0.249

Low

1271098

CEP76
Centrosomal protein of 76 kDa

1

0

High-throughput

0.249

Low

1271113

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1271129

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.249

Low

1271142

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1271150

ARGAL
Rho guanine nucleotide exchange factor 10-like protein

1

0

High-throughput

0.249

Low

1271151

MYO10
Unconventional myosin-X

1

0

Small-scale

0.249

Low

1271157

TMPS4
Transmembrane protease serine 4

1

0

High-throughput

0.249

Low

1271163

DJC28
DnaJ homolog subfamily C member 28

1

0

High-throughput

0.249

Low

1271173

ASB1
Ankyrin repeat and SOCS box protein 1

1

0

High-throughput

0.249

Low

326892

ARK73
Aldo-keto reductase family 7 member A3

1

0

High-throughput

0.232

Low

1249705

CLC4G
C-type lectin domain family 4 member G

1

0

Small-scale

0.232

Low

1271097

CAMKV
CaM kinase-like vesicle-associated protein

1

0

High-throughput

0.232

Low

1271115

MF14A
Hippocampus abundant transcript 1 protein

1

0

High-throughput

0.232

Low

1271156

ITM2C
Integral membrane protein 2C

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025