HitPredict

Interactor 1: SV2B (Q7L1I2)
Synaptic vesicle glycoprotein 2B
Gene: SV2B

Interactor 2: SYT2 (Q8N9I0)
Synaptotagmin-2 (Synaptotagmin II) (SytII)
Gene: SYT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3795
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030672 - synaptic vesicle membrane GO:2000300 - regulation of synaptic vesicle exocytosis
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 683 Hs			1 419
+	Hs
		639144 SV2B_HUMAN (1-683): 4.03e-159: 476: 100.00		SYT1_HUMAN (4-419): 8.87e-111: 333: 73.05
+	Mm
		855295 SV2C_MOUSE (23-683): 1.94e-129: 401: 61.63		SYT1_MOUSE (4-419): 7.97e-111: 333: 72.81
+	Hs
		639137 SV2C_HUMAN (23-683): 2.13e-126: 393: 61.78		SYT1_HUMAN (4-419): 8.87e-111: 333: 73.05
+	Rn
		639914 SV2A_RAT (18-682): 1.39e-121: 381: 63.86		SYT1_RAT (4-419): 2.26e-111: 335: 72.81
+	Mm
		855301 Q8JZZ9_MOUSE (505-683): 9.15e-77: 245: 93.86		SYT1_MOUSE (4-419): 7.97e-111: 333: 72.81