HitPredict

Interactor 1: SHIP1 (Q92835)
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (EC 3.1.3.86) (Inositol polyphosphate-5-phosphatase D) (EC 3.1.3.56) (Inositol polyphosphate-5-phosphatase of 145 kDa) (SIP-145) (Phosphatidylinositol 4,5-bisphosphate 5-phosphatase) (EC 3.1.3.36) (SH2 domain-containing inositol 5'-phosphatase 1) (SH2 domain-containing inositol phosphatase 1) (SHIP-1) (p150Ship) (hp51CN)
Gene: INPP5D

Interactor 2: SLAF7 (Q9NQ25)
SLAM family member 7 (CD2 subset 1) (CD2-like receptor-activating cytotoxic cells) (CRACC) (Membrane protein FOAP-12) (Novel Ly9) (Protein 19A) (CD antigen CD319)
Gene: SLAMF7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36749634
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1189 Hs			1 335
+	Hs
		1030743 SHIP1_HUMAN (1-1189): 0: 883: 100.00		SLAF1_HUMAN (3-325): 4.68e-59: 195: 18.75
+	Hs
		1271565 SHIP1_HUMAN (1-1189): 0: 883: 100.00		CD244_HUMAN (1-334): 1.81e-53: 181: 19.72
+	Hs
		1271566 SHIP1_HUMAN (1-1189): 0: 883: 100.00		LY9_HUMAN (19-298): 1.41e-44: 163: 26.06
+	Mm
		1322348 SHIP1_MOUSE (1-1189): 0: 858: 87.11		SLAF1_MOUSE (3-325): 6.34e-46: 161: 18.52
+	Hs
		590610 SHIP1_HUMAN (1-1189): 0: 883: 100.00		CD22_HUMAN (11-224): 7.17e-11: 65.2: 16.59
+	Mm
		722908 SHIP1_MOUSE (1-1189): 0: 858: 87.11		CD22_MOUSE (6-217): 8.53e-13: 71.4: 13.24
+	Hs
		176495 SHIP2_HUMAN (3-1169): 0: 697: 39.77		CD244_HUMAN (1-334): 1.81e-53: 181: 19.72
+	Hs
		243158 SH21A_HUMAN (7-101): 2.92e-20: 89.7: 45.26		SLAF7_HUMAN (1-335): 5.07e-65: 210: 100.00
+	Hs
		243137 SH21A_HUMAN (7-101): 2.92e-20: 89.7: 45.26		SLAF1_HUMAN (3-325): 4.68e-59: 195: 18.75
+	Hs
		243155 SH21A_HUMAN (7-101): 2.92e-20: 89.7: 45.26		CD244_HUMAN (1-334): 1.81e-53: 181: 19.72
+	Hs
		243161 SH21A_HUMAN (7-101): 2.92e-20: 89.7: 45.26		SLAF5_HUMAN (1-335): 1.9e-50: 172: 29.10
+	Mm
		292400 SH21A_MOUSE (7-116): 3.21e-22: 95.1: 44.55		SLAF1_MOUSE (3-325): 6.34e-46: 161: 18.52
+	Hs
		243153 SH21A_HUMAN (7-101): 2.92e-20: 89.7: 45.26		SLAF6_HUMAN (9-335): 1.13e-47: 165: 27.67
+	Hs
		243157 SH21A_HUMAN (7-101): 2.92e-20: 89.7: 45.26		LY9_HUMAN (19-298): 1.41e-44: 163: 26.06
+	Hs
		243129 SH21A_HUMAN (7-101): 2.92e-20: 89.7: 45.26		CD22_HUMAN (11-224): 7.17e-11: 65.2: 16.59