Interactor 1: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Interactor 2: CSN8 (Q99627)
COP9 signalosome complex subunit 8 (SGN8) (Signalosome subunit 8) (COP9 homolog) (hCOP9) (JAB1-containing signalosome subunit 8)
Gene: COPS8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 28514442, 27173435, 9707402, 33961781, 26186194, 31950832, 19615732, 18850735, 21145461, 19295130, 23636414, 20399188, 25043011
Identification Methods affinity chromatography technology, biochemical, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CSN5_C~CSN8_PSD8_EIF3K
Common GO terms GO:0000338 - protein deneddylation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 4 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 334
Hs

1 209
+ Mm
+ At
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024