HitPredict

Interactor 1: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Interactor 2: YTDC2 (Q9H6S0)
3'-5' RNA helicase YTHDC2 (EC 3.6.4.13) (YTH domain-containing protein 2) (hYTHDC2)
Gene: YTHDC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	31950832, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 1430
+	Hs
		195505 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		DHX15_HUMAN (164-482): 6.33e-112: 374: 26.65
+	Hs
		1272605 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		DHX36_HUMAN (71-521): 4.15e-100: 346: 27.63
+	Hs
		1190216 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		DHX29_HUMAN (139-425): 6.43e-94: 334: 39.32
+	Hs
		994274 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		DHX9_HUMAN (119-458): 1.05e-90: 323: 32.77
+	Hs
		130647 PSDE_HUMAN (50-331): 1.67e-79: 246: 31.51		DHX15_HUMAN (164-482): 6.33e-112: 374: 26.65
+	Hs
		1158093 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		DHX57_HUMAN (155-408): 6.08e-60: 229: 49.23
+	Hs
		130863 PSDE_HUMAN (50-331): 1.67e-79: 246: 31.51		DHX9_HUMAN (119-458): 1.05e-90: 323: 32.77
+	Hs
		177050 EIF3H_HUMAN (52-320): 2.17e-66: 214: 18.57		DHX29_HUMAN (139-425): 6.43e-94: 334: 39.32
+	Hs
		1183960 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		DHX30_HUMAN (163-405): 4.25e-41: 167: 39.39
+	Hs
		1138814 MYSM1_HUMAN (39-172): 3.5e-29: 119: 23.29		DHX40_HUMAN (191-481): 5.27e-100: 340: 25.40