Interactor 1: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5
Interactor 2: CSN7B (Q9H9Q2)
COP9 signalosome complex subunit 7b (SGN7b) (Signalosome subunit 7b) (JAB1-containing signalosome subunit 7b)
Gene: COPS7B
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.984 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 27173435, 31444342, 32034103, 31950832, 19615732, 18850735, 21145461, 16624822, 19295130, 27833851, 28514442, 33961781, 37091236, 20399188 |
| Identification Methods | affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CSN5_C~CSN7a_helixI, JAB~PCI |
| Common GO terms | GO:0000338 - protein deneddylation GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol and 2 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
|
|
|||||||||||||
| + | Mm |   |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | Hs | |
 |
|||||||||||
| + | An | |
|
|||||||||||
| + | Ce | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Ce | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Sp | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Ce | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
